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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA003387 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA003387, RRID:AB_1846356
- Product name
- Anti-CDK1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CDK1, Gene description: cyclin-dependent kinase 1, Alternative Gene Names: CDC2, CDC28A, Validated applications: WB, IHC, ICC, Uniprot ID: P06493, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mechanisms of synergistic suppression of ALK-positive lung cancer cell growth by the combination of ALK and SHP2 inhibitors
CDC7-independent G1/S transition revealed by targeted protein degradation.
Identification of cell division cycle 20 as a candidate biomarker and potential therapeutic target in bladder cancer using bioinformatics analysis
CDK1 dependent phosphorylation of hTERT contributes to cancer progression
Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death.
Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer
Residual Cdk1/2 activity after DNA damage promotes senescence.
Vulnerability of newly synthesized proteins to proteostasis stress
An Inverse Switch in DNA Base Excision and Strand Break Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells
Berry M, Bland A, Ashton J
Scientific Reports 2023;13(1)
Scientific Reports 2023;13(1)
CDC7-independent G1/S transition revealed by targeted protein degradation.
Suski JM, Ratnayeke N, Braun M, Zhang T, Strmiska V, Michowski W, Can G, Simoneau A, Snioch K, Cup M, Sullivan CM, Wu X, Nowacka J, Branigan TB, Pack LR, DeCaprio JA, Geng Y, Zou L, Gygi SP, Walter JC, Meyer T, Sicinski P
Nature 2022 May;605(7909):357-365
Nature 2022 May;605(7909):357-365
Identification of cell division cycle 20 as a candidate biomarker and potential therapeutic target in bladder cancer using bioinformatics analysis
Shen P, He X, Lan L, Hong Y, Lin M
Bioscience Reports 2020;40(7)
Bioscience Reports 2020;40(7)
CDK1 dependent phosphorylation of hTERT contributes to cancer progression
Yasukawa M, Ando Y, Yamashita T, Matsuda Y, Shoji S, Morioka M, Kawaji H, Shiozawa K, Machitani M, Abe T, Yamada S, Kaneko M, Kato Y, Furuta Y, Kondo T, Shirouzu M, Hayashizaki Y, Kaneko S, Masutomi K
Nature Communications 2020;11(1)
Nature Communications 2020;11(1)
Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death.
Marlier Q, Jibassia F, Verteneuil S, Linden J, Kaldis P, Meijer L, Nguyen L, Vandenbosch R, Malgrange B
Cell death discovery 2018;4:43
Cell death discovery 2018;4:43
Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer
Goto Y, Kurozumi A, Arai T, Nohata N, Kojima S, Okato A, Kato M, Yamazaki K, Ishida Y, Naya Y, Ichikawa T, Seki N
British Journal of Cancer 2017;117(3):409-420
British Journal of Cancer 2017;117(3):409-420
Residual Cdk1/2 activity after DNA damage promotes senescence.
Müllers E, Silva Cascales H, Burdova K, Macurek L, Lindqvist A
Aging cell 2017 Jun;16(3):575-584
Aging cell 2017 Jun;16(3):575-584
Vulnerability of newly synthesized proteins to proteostasis stress
Xu G, Pattamatta A, Hildago R, Pace M, Brown H, Borchelt D
Journal of Cell Science 2016;129(9):1892-1901
Journal of Cell Science 2016;129(9):1892-1901
An Inverse Switch in DNA Base Excision and Strand Break Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells
Singh K, Sousa M, Zub K, Aas P, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk N, Slupphaug G
PLoS ONE 2013;8(2):e55493
PLoS ONE 2013;8(2):e55493
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human tonsil and pancreas tissues using HPA003387 antibody. Corresponding CDK1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
