11666-1-AP

antibody from Proteintech Group

Targeting: WSB1 DKFZp564A122, DKFZp564B0482, SWIP1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

11666-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11666-1-AP, RRID:AB_10949076

Product name

WSB1 antibody

Antibody type

Polyclonal

Description

WSB1 antibody (Cat. #11666-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

WSB1 promotes prostate cancer malignancy through OTUD4-mediated ISOC2 stabilization and P16INK4a suppression.

Sun J, Wang F, Feng Y, Qiu X, Qu W, He X, Xie J, Li G
American journal of cancer research 2025;15(10):4434-4451

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S-nitrosylation of pVHL regulates β(2) adrenergic receptor function.

Grimmett ZW, Hayashi H, Raffay TM, Lin J, Premont RT, Stamler JS
Proceedings of the National Academy of Sciences of the United States of America 2025 Sep 16;122(37):e2515326122

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circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis.

Tang G, Liu J, Gao X, Tang W, Chen J, Wu M, Lv Z, Zhang Y, Cai Y, Qi L
International journal of biological macromolecules 2024 Jan;256(Pt 1):128338

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Single-cell protein activity analysis reveals a novel subpopulation of chondrocytes and the corresponding key master regulator proteins associated with anti-senescence and OA progression.

Guang Z, Min Z, Jun-Tan L, Tian-Xu D, Xiang G
Frontiers in immunology 2023;14:1077003

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BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.

Liu M, Yu Z, Yang F, Zhao Z, Zhou M, Wang C, Zhang B, Liang G, Liu X, Shao J
Toxicology 2023 Aug 1;494:153581

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WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation.

Kim JJ, Lee SB, Yi SY, Han SA, Kim SH, Lee JM, Tong SY, Yin P, Gao B, Zhang J, Lou Z
Cell research 2017 Feb;27(2):274-293

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Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells.

Cao J, Wang Y, Dong R, Lin G, Zhang N, Wang J, Lin N, Gu Y, Ding L, Ying M, He Q, Yang B
Cancer research 2015 Nov 15;75(22):4839-51

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WSB1 promotes tumor metastasis by inducing pVHL degradation.

Kim JJ, Lee SB, Jang J, Yi SY, Kim SH, Han SA, Lee JM, Tong SY, Vincelette ND, Gao B, Yin P, Evans D, Choi DW, Qin B, Liu T, Zhang H, Deng M, Jen J, Zhang J, Wang L, Lou Z
Genes & development 2015 Nov 1;29(21):2244-57

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

SGC-7901 cells were subjected to SDS PAGE followed by western blot with 11666-1-AP(WSB1 antibody) at dilution of 1:1000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using WSB1 antibody 11666-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human prostate cancer using 11666-1-AP(WSB1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue