Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 130-00016-100 - Provider product page
- Provider
- RayBiotech, Inc.
- Product name
- Rabbit Anti-Human TIMP1
- Antibody type
- Polyclonal
- Antigen
- a synthetic peptide (TIMP1).
- Description
- Tissue Inhibitor of Metalloproteinases-1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified from rabbit serum by Protein G affinity chromatography
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
This antibody was produced from a r
abbit immunized with this peptide c
onjugated with KLH. The IgG fractio
n was purified from rabbit serum by
Protein G affinity chromatography- Isotype
- IgG
- Vial size
- 100 µg
- Handling
- Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.
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