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- Antibody Data
- Antigen structure
- References [83]
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- Product number
- 16644-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- TIMP1 antibody
- Antibody type
- Polyclonal
- Description
- TIMP1 antibody (Cat. #16644-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells.
Network pharmacology and experimental verification to decode the action of Qing Fei Hua Xian Decotion against pulmonary fibrosis.
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Identification and validation of anoikis-related genes to clarify the prognosis and immune mechanisms of patients with low-grade glioma.
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway.
Dual effect of vitamin D(3) on breast cancer-associated fibroblasts.
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Unraveling TIMP1: a multifaceted biomarker in colorectal cancer.
Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD(+)/SIRT1 axis.
Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer.
Long-read sequencing reveals the landscape of aberrant alternative splicing and novel therapeutic target in colorectal cancer.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Identification of TIMP1 as an inflammatory biomarker associated with temporal lobe epilepsy based on integrated bioinformatics and experimental analyses.
Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d-galactose induced-aging mice.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer's disease mice.
Qianjin Wenwu decoction suppresses renal interstitial fibrosis by enhancing the degradation of extracellular matrix in mice with unilateral ureteral obstruction.
Network Pharmacology-Based Prediction and Verification of the Potential Targets of Pinoresinol Diglucoside for OA Treatment.
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
β3 adrenoceptor agonist mirabegron protects against right ventricular remodeling and drives Drp1 inhibition.
Protective role of Achyranthes bidentata polysaccharides against chondrocyte extracellular matrix degeneration through lncRNA GAS5 in osteoarthritis.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Investigating the mechanism of Xian-ling-lian-xia-fang for inhibiting vasculogenic mimicry in triple negative breast cancer via blocking VEGF/MMPs pathway.
Combination of ferulic acid, ligustrazine and tetrahydropalmatine inhibits invasion and metastasis through MMP/TIMP signaling in endometriosis.
Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases.
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
SPARC knockdown attenuated TGF-β1-induced fibrotic effects through Smad2/3 pathways in human pterygium fibroblasts.
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Decursin inhibits the growth of HeLa cervical cancer cells through PI3K/Akt signaling.
Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.
Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertension.
Human umbilical cord-derived mesenchymal stem cells improve the function of liver in rats with acute-on-chronic liver failure via downregulating Notch and Stat1/Stat3 signaling.
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Identification and development of a novel invasion-related gene signature for prognosis prediction in colon adenocarcinoma.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy.
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Galectin-1 Overexpression Activates the FAK/PI3K/AKT/mTOR Pathway and Is Correlated with Upper Urinary Urothelial Carcinoma Progression and Survival.
Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia.
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
A Compound of Chinese Herbs Protects against Alcoholic Liver Fibrosis in Rats via the TGF-β1/Smad Signaling Pathway.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism.
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway.
Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Effects of IL-1β on MMP-9 Expression in Cementoblast-Derived Cell Line and MMP-Mediated Degradation of Type I Collagen.
Anti-endometriosis Mechanism of Jiawei Foshou San Based on Network Pharmacology.
AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation.
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
Fang RY, Liu YW, Goan YG, Lin JJ, Su JH, Wu WT, Wu YJ
Advances in pharmacological and pharmaceutical sciences 2024;2024:6695837
Advances in pharmacological and pharmaceutical sciences 2024;2024:6695837
Network pharmacology and experimental verification to decode the action of Qing Fei Hua Xian Decotion against pulmonary fibrosis.
Ke HL, Li RJ, Yu CC, Wang XP, Wu CY, Zhang YW
PloS one 2024;19(6):e0305903
PloS one 2024;19(6):e0305903
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Yuan Q, Fang Y, Guo J, Zhang Z, Liao J, Kuang J
Toxicology and applied pharmacology 2024 Mar;484:116845
Toxicology and applied pharmacology 2024 Mar;484:116845
Identification and validation of anoikis-related genes to clarify the prognosis and immune mechanisms of patients with low-grade glioma.
Wang J, Liu Y, Qian M, Xu W, Chen J, Deng Y, Luo R, Chen J, Jia W, Liu L, Tian C
Biochemical and biophysical research communications 2024 Jun 4;711:149894
Biochemical and biophysical research communications 2024 Jun 4;711:149894
The mechanism of adipose mesenchymal stem cells to stabilize the immune microenvironment of pelvic floor injury by regulating pyroptosis and promoting tissue repair.
Wu X, Zhang F, Mao X, Xu F, Ding X, Sun X, Wang J
Materials today. Bio 2024 Feb;24:100910
Materials today. Bio 2024 Feb;24:100910
KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway.
Zhang H, Xia T, Xia Z, Zhou H, Li Z, Wang W, Zhai X, Jin B
Cellular and molecular life sciences : CMLS 2024 Feb 19;81(1):96
Cellular and molecular life sciences : CMLS 2024 Feb 19;81(1):96
Dual effect of vitamin D(3) on breast cancer-associated fibroblasts.
Łabędź N, Anisiewicz A, Stachowicz-Suhs M, Banach J, Kłopotowska D, Maciejczyk A, Gazińska P, Piotrowska A, Dzięgiel P, Matkowski R, Wietrzyk J
BMC cancer 2024 Feb 15;24(1):209
BMC cancer 2024 Feb 15;24(1):209
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
Zhou S, Guo L, Cui X, Zhang X, Yang Y, Zhang M, Zhang P
Cellular signalling 2024 Aug;120:111217
Cellular signalling 2024 Aug;120:111217
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
Unraveling TIMP1: a multifaceted biomarker in colorectal cancer.
Qiu X, Quan G, Ou W, Wang P, Huang X, Li X, Shen Y, Yang W, Wang J, Wu X
Frontiers in genetics 2023;14:1265137
Frontiers in genetics 2023;14:1265137
Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD(+)/SIRT1 axis.
Wu K, Li B, Ma Y, Tu T, Lin Q, Zhu J, Zhou Y, Liu N, Liu Q
Frontiers in endocrinology 2023;14:1099134
Frontiers in endocrinology 2023;14:1099134
Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer.
Pan Z, Lin H, Fu Y, Zeng F, Gu F, Niu G, Fang J, Gu B
Frontiers in immunology 2023;14:1086898
Frontiers in immunology 2023;14:1086898
Long-read sequencing reveals the landscape of aberrant alternative splicing and novel therapeutic target in colorectal cancer.
Sun Q, Han Y, He J, Wang J, Ma X, Ning Q, Zhao Q, Jin Q, Yang L, Li S, Li Y, Zhi Q, Zheng J, Dong D
Genome medicine 2023 Sep 21;15(1):76
Genome medicine 2023 Sep 21;15(1):76
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
Meng Q, Bi Y, Feng H, Ding X, Zhang S, Chen Q, Wang L, Zhang Q, Li Y, Tong H, Wu L, Bian H
International immunopharmacology 2023 Mar;116:109825
International immunopharmacology 2023 Mar;116:109825
PTEN Inhibitor Treatment Lowers Muscle Plasma Membrane Damage and Enhances Muscle ECM Homeostasis after High-Intensity Eccentric Exercise in Mice.
Wu B, Shi L, Wu Y
International journal of molecular sciences 2023 Jun 9;24(12)
International journal of molecular sciences 2023 Jun 9;24(12)
Identification of TIMP1 as an inflammatory biomarker associated with temporal lobe epilepsy based on integrated bioinformatics and experimental analyses.
He Y, Zhang H, Ma L, Li J, Wang F, Zhou H, Zhang G, Wen Y
Journal of neuroinflammation 2023 Jun 26;20(1):151
Journal of neuroinflammation 2023 Jun 26;20(1):151
Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.
Guo M, Zhu C, Fu R, Ma X, Duan Z, Fan D
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Su W, Zheng X, Zhou H, Yang S, Zhu X
Molecular immunology 2023 Jul;159:46-57
Molecular immunology 2023 Jul;159:46-57
Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d-galactose induced-aging mice.
Zeng J, An M, Tian W, Wang K, Du B, Li P
Journal of the science of food and agriculture 2023 Jul;103(9):4470-4480
Journal of the science of food and agriculture 2023 Jul;103(9):4470-4480
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Chen Y, Yin H, Sun J, Zhang G, Zhang Y, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer's disease mice.
Taylor X, Clark IM, Fitzgerald GJ, Oluoch H, Hole JT, DeMattos RB, Wang Y, Pan F
Molecular neurodegeneration 2023 Aug 30;18(1):59
Molecular neurodegeneration 2023 Aug 30;18(1):59
Qianjin Wenwu decoction suppresses renal interstitial fibrosis by enhancing the degradation of extracellular matrix in mice with unilateral ureteral obstruction.
Jin C, Wu X, You Y, Wang Y, Wu J, Zuo A, Zheng Y, Guo J
Chinese journal of natural medicines 2023 Apr;21(4):253-262
Chinese journal of natural medicines 2023 Apr;21(4):253-262
Network Pharmacology-Based Prediction and Verification of the Potential Targets of Pinoresinol Diglucoside for OA Treatment.
Lou H, Zhang Y, Fang J, Jin Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9733742
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9733742
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C
International journal of biological sciences 2022;18(6):2527-2539
International journal of biological sciences 2022;18(6):2527-2539
Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Hu Z, Wang Y, Gao X, Zhang Y, Liu C, Zhai Y, Chang X, Li H, Li Y, Lou J, Li C
Frontiers in pharmacology 2022;13:893307
Frontiers in pharmacology 2022;13:893307
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Li H, You S, Yang X, Liu S, Hu L
Biomaterials advances 2022 Mar;134:112715
Biomaterials advances 2022 Mar;134:112715
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Ayesha M, Majid A, Zhao D, Greenaway FT, Yan N, Liu Q, Liu S, Sun MZ
Journal of advanced research 2022 Feb;36:147-161
Journal of advanced research 2022 Feb;36:147-161
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
β3 adrenoceptor agonist mirabegron protects against right ventricular remodeling and drives Drp1 inhibition.
Zhao L, Luo H, Li T, Zhao X, Liu Y
Cardiovascular diagnosis and therapy 2022 Dec;12(6):815-827
Cardiovascular diagnosis and therapy 2022 Dec;12(6):815-827
Protective role of Achyranthes bidentata polysaccharides against chondrocyte extracellular matrix degeneration through lncRNA GAS5 in osteoarthritis.
Fu C, Qiu Z, Huang Y, Mei Y, Lin Q, Zeng J, Zhong W, Ma D
Experimental and therapeutic medicine 2022 Aug;24(2):532
Experimental and therapeutic medicine 2022 Aug;24(2):532
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
Investigating the mechanism of Xian-ling-lian-xia-fang for inhibiting vasculogenic mimicry in triple negative breast cancer via blocking VEGF/MMPs pathway.
Li F, Shi Y, Zhang Y, Yang X, Wang Y, Jiang K, Hua C, Wu C, Sun C, Qin Y, Liu S
Chinese medicine 2022 Apr 4;17(1):44
Chinese medicine 2022 Apr 4;17(1):44
Combination of ferulic acid, ligustrazine and tetrahydropalmatine inhibits invasion and metastasis through MMP/TIMP signaling in endometriosis.
Tan Y, Zhang C, Zhang Y, Dai X, Wei Q, Wei J, Xu P, Chen Y
PeerJ 2021;9:e11664
PeerJ 2021;9:e11664
Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases.
Fang Z, Kim HG, Huang M, Chowdhury K, Li MO, Liangpunsakul S, Dong XC
Cellular and molecular gastroenterology and hepatology 2021;12(3):921-942
Cellular and molecular gastroenterology and hepatology 2021;12(3):921-942
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Gao XX, Liu CH, Hu ZL, Li HY, Chang X, Li YY, Zhang YY, Zhai Y, Li CQ
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
SPARC knockdown attenuated TGF-β1-induced fibrotic effects through Smad2/3 pathways in human pterygium fibroblasts.
Fan J, Zhang X, Jiang Y, Chen L, Sheng M, Chen Y
Archives of biochemistry and biophysics 2021 Nov 30;713:109049
Archives of biochemistry and biophysics 2021 Nov 30;713:109049
Differentially expressed genes induced by β-caryophyllene in a rat model of cerebral ischemia-reperfusion injury.
Liu S, Liu J, Wang Y, Deng L, Chen S, Wang X, Zuo T, Hu Q, Rao J, Wang Q, Dong Z
Life sciences 2021 May 15;273:119293
Life sciences 2021 May 15;273:119293
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Miao Z, Ding Y, Bi Y, Chen M, Cao X, Wang F
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Decursin inhibits the growth of HeLa cervical cancer cells through PI3K/Akt signaling.
Zhu ML, Li JC, Wang L, Zhong X, Zhang YW, Tan RZ, Wang HL, Fan JM, Wang L
Journal of Asian natural products research 2021 Jun;23(6):584-595
Journal of Asian natural products research 2021 Jun;23(6):584-595
Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.
Shi L, Tan X, Liu X, Yu J, Bota-Rabassedas N, Niu Y, Luo J, Xi Y, Zong C, Creighton CJ, Glenn JS, Wang J, Kurie JM
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 22;118(25)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 22;118(25)
Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertension.
Pang W, Zhang Z, Zhang Y, Zhang M, Miao R, Yang Y, Xie W, Wan J, Zhai Z, Wang C
Journal of thrombosis and thrombolysis 2021 Jul;52(1):48-58
Journal of thrombosis and thrombolysis 2021 Jul;52(1):48-58
Human umbilical cord-derived mesenchymal stem cells improve the function of liver in rats with acute-on-chronic liver failure via downregulating Notch and Stat1/Stat3 signaling.
He Y, Guo X, Lan T, Xia J, Wang J, Li B, Peng C, Chen Y, Hu X, Meng Z
Stem cell research & therapy 2021 Jul 13;12(1):396
Stem cell research & therapy 2021 Jul 13;12(1):396
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
Wang R, Zhang D, Tang D, Sun K, Peng J, Zhu W, Yin S, Wu Y
International immunopharmacology 2021 Jan;90:107151
International immunopharmacology 2021 Jan;90:107151
PPARγ/NF-κB and TGF-β1/Smad pathway are involved in the anti-fibrotic effects of levo-tetrahydropalmatine on liver fibrosis.
Yu Q, Cheng P, Wu J, Guo C
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Journal of cellular and molecular medicine 2021 Feb;25(3):1645-1660
Identification and development of a novel invasion-related gene signature for prognosis prediction in colon adenocarcinoma.
Liu J, Jiang C, Xu C, Wang D, Shen Y, Liu Y, Gu L
Cancer cell international 2021 Feb 12;21(1):101
Cancer cell international 2021 Feb 12;21(1):101
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
Feng B, Zhao C, Li J, Yu J, Zhang Y, Zhang X, Tian T, Zhao L
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Chemical & pharmaceutical bulletin 2020;68(10):962-970
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy.
Luo H, Liu T, Yang H, Ye H, Luo X
Journal of ophthalmology 2020;2020:4929634
Journal of ophthalmology 2020;2020:4929634
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, Xiong Z, Yang S
BioMed research international 2020;2020:3126182
BioMed research international 2020;2020:3126182
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
Zhang YY, Luo LM, Wang YX, Zhu N, Zhao TJ, Qin L
Journal of Cancer 2020;11(14):4261-4273
Journal of Cancer 2020;11(14):4261-4273
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Galectin-1 Overexpression Activates the FAK/PI3K/AKT/mTOR Pathway and Is Correlated with Upper Urinary Urothelial Carcinoma Progression and Survival.
Su YL, Luo HL, Huang CC, Liu TT, Huang EY, Sung MT, Lin JJ, Chiang PH, Chen YT, Kang CH, Cheng YT
Cells 2020 Mar 26;9(4)
Cells 2020 Mar 26;9(4)
Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia.
Ou Y, Zhu L, Wei X, Bai S, Chen M, Chen H, Zhang J
Cell death & disease 2020 Jun 25;11(6):479
Cell death & disease 2020 Jun 25;11(6):479
Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice.
Li J, Liu L, Zhao Q, Chen M
Digestive diseases and sciences 2020 Jul;65(7):1971-1979
Digestive diseases and sciences 2020 Jul;65(7):1971-1979
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X
International journal of molecular medicine 2020 Jan;45(1):175-185
International journal of molecular medicine 2020 Jan;45(1):175-185
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Wang Y, Su NX, Pan SG, Ge XP, Dai XP
Pharmaceutical biology 2020 Dec;58(1):878-885
Pharmaceutical biology 2020 Dec;58(1):878-885
Transcriptome sequencing reveals fibrotic associated-genes involved in bovine mammary fibroblasts with Staphylococcus aureus.
Miao Z, Ding Y, Zhao N, Chen X, Cheng H, Wang J, Liu Y, Wang F
The international journal of biochemistry & cell biology 2020 Apr;121:105696
The international journal of biochemistry & cell biology 2020 Apr;121:105696
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
You S, Liu S, Dong X, Li H, Zhu Y, Hu L
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
Zhou X, Xiong J, Lu S, Luo L, Chen ZL, Yang F, Jin F, Wang Y, Ma Q, Luo YY, Wang YJ, Zhou JB, Liu P, Zhao L
The American journal of Chinese medicine 2019;47(7):1541-1569
The American journal of Chinese medicine 2019;47(7):1541-1569
A Compound of Chinese Herbs Protects against Alcoholic Liver Fibrosis in Rats via the TGF-β1/Smad Signaling Pathway.
Li X, Liu Y, Yue W, Tan Y, Wang H, Zhang L, Chen J
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9121347
Evidence-based complementary and alternative medicine : eCAM 2019;2019:9121347
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism.
Liu X, Qu C, Shi S, Ye T, Wang L, Liu S, Zhang C, Liang J, Hu D, Yang B
Frontiers in physiology 2019;10:1346
Frontiers in physiology 2019;10:1346
Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro.
Chen J, Li D, Luo E
International immunopharmacology 2019 Sep;74:105683
International immunopharmacology 2019 Sep;74:105683
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Cecen B, Keles D, Oktay G, Kozaci LD
Chemico-biological interactions 2019 Sep 1;310:108730
Chemico-biological interactions 2019 Sep 1;310:108730
Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway.
Chen IH, Luo HL, Su YL, Huang CC, Chiang PH, Yu CC, Lee NL, Lin JJ, Sung MT
Molecules (Basel, Switzerland) 2019 Oct 15;24(20)
Molecules (Basel, Switzerland) 2019 Oct 15;24(20)
Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
Yu H, Zeng R, Lin Y, Li X, Tasneem S, Yang Z, Qiu YX, Li B, Wang YH, Cai X, Wang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 May;58:152876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 May;58:152876
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
Wang J, Du L, Fu Y, Jiang P, Wang X
BMC oral health 2019 May 14;19(1):84
BMC oral health 2019 May 14;19(1):84
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, Wang J, Feng X
Pain physician 2019 Mar;22(2):155-164
Pain physician 2019 Mar;22(2):155-164
Effects of IL-1β on MMP-9 Expression in Cementoblast-Derived Cell Line and MMP-Mediated Degradation of Type I Collagen.
Du M, Wang Y, Liu Z, Wang L, Cao Z, Zhang C, Hao Y, He H
Inflammation 2019 Apr;42(2):413-425
Inflammation 2019 Apr;42(2):413-425
Anti-endometriosis Mechanism of Jiawei Foshou San Based on Network Pharmacology.
Chen Y, Wei J, Zhang Y, Sun W, Li Z, Wang Q, Xu X, Li C, Li P
Frontiers in pharmacology 2018;9:811
Frontiers in pharmacology 2018;9:811
AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
Fang CC, Wu CF, Liao YJ, Huang SF, Chen M, Chen YA
Scientific reports 2018 Sep 14;8(1):13802
Scientific reports 2018 Sep 14;8(1):13802
Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.
Xia Y, Yu B, Ma C, Tu Y, Zhai L, Yang Y, Liu D, Liu Y, Wu H, Dan H, You P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1332-1338
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
He XX, Shi LL, Qiu MJ, Li QT, Wang MM, Xiong ZF, Yang SL
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Cryptotanshinone inhibits the growth and invasion of colon cancer by suppressing inflammation and tumor angiogenesis through modulating MMP/TIMP system, PI3K/Akt/mTOR signaling and HIF-1α nuclear translocation.
Zhang L, Chen C, Duanmu J, Wu Y, Tao J, Yang A, Yin X, Xiong B, Gu J, Li C, Liu Z
International immunopharmacology 2018 Dec;65:429-437
International immunopharmacology 2018 Dec;65:429-437
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
Tian YS, Chen KC, Zulkefli ND, Maner RS, Hsieh CL
Molecules (Basel, Switzerland) 2018 Dec 14;23(12)
Molecules (Basel, Switzerland) 2018 Dec 14;23(12)
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
Wu DQ, Zhong HM, Ding QH, Ba L
BMC complementary and alternative medicine 2014 Nov 15;14:444
BMC complementary and alternative medicine 2014 Nov 15;14:444
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