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- Antibody Data
- Antigen structure
- References [16]
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- Immunohistochemistry [1]
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- Product number
- PA1385 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for TIMP 1/TIMP1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. TIMP 1/TIMP1 information: Molecular Weight: 23171 MW; Subcellular Localization: Secreted ; Tissue Specificity: Detected in rheumatoid synovial fluid (at protein level).
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references 17β-estradiol inhibits TGF-β-induced collagen gel contraction mediated by human Tenon fibroblasts via Smads and MAPK signaling pathways.
Trophoblast cellular adhesion molecule expression regulated by different genes and their correlation with pregnancy-induced hypertension.
Timosaponin BII inhibits TGF-β mediated epithelial-mesenchymal transition through Smad-dependent pathway during pulmonary fibrosis.
Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo.
Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia.
Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice.
Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis.
Effect of focal mild hypothermia on expression of MMP-9, TIMP-1, Tau-1 and β-APP in rats with cerebral ischaemia/reperfusion injury.
Anti-fibrotic effects of puerarin on CCl4-induced hepatic fibrosis in rats possibly through the regulation of PPAR-γ expression and inhibition of PI3K/Akt pathway.
The effect of 2,3,4',5-tetrahydroxystilbene-2-0-β-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms.
Acipimox attenuates atherosclerosis and enhances plaque stability in ApoE-deficient mice fed a palmitate-rich diet.
Synthetic gelatinases inhibitor attenuates electromagnetic pulse-induced blood-brain barrier disruption by inhibiting gelatinases-mediated ZO-1 degradation in rats.
Noninvasive limb ischemic preconditioning protects against myocardial I/R injury in rats.
Inhibition effect of Guizhi-Fuling-decoction on the invasion of human cervical cancer.
Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats.
Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis.
Yang CC, Liu MJ, Li YZ, Xu ZH, Liu Y, Guo ZH, Li BH, Yang XX
International journal of ophthalmology 2023;16(9):1441-1449
International journal of ophthalmology 2023;16(9):1441-1449
Trophoblast cellular adhesion molecule expression regulated by different genes and their correlation with pregnancy-induced hypertension.
Chen Y, Fan Y, Pan X, Liao Y, Xiang G
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 30;69(12):26-32
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Nov 30;69(12):26-32
Timosaponin BII inhibits TGF-β mediated epithelial-mesenchymal transition through Smad-dependent pathway during pulmonary fibrosis.
Ding D, Shen X, Yu L, Zheng Y, Liu Y, Wang W, Liu L, Zhao Z, Nian S, Liu L
Phytotherapy research : PTR 2023 Jul;37(7):2787-2799
Phytotherapy research : PTR 2023 Jul;37(7):2787-2799
Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo.
Yang F, Luo L, Zhu ZD, Zhou X, Wang Y, Xue J, Zhang J, Cai X, Chen ZL, Ma Q, Chen YF, Wang YJ, Luo YY, Liu P, Zhao L
Frontiers in pharmacology 2017;8:929
Frontiers in pharmacology 2017;8:929
Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia.
Deng CL, Ling ST, Liu XQ, Zhao YJ, Lv YF
Experimental and therapeutic medicine 2015 Mar;9(3):992-998
Experimental and therapeutic medicine 2015 Mar;9(3):992-998
Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice.
Wang B, Liang S, Wang Y, Zhu XQ, Gong W, Zhang HQ, Li Y, Xia CM
PLoS neglected tropical diseases 2015 Jan;9(1):e0003434
PLoS neglected tropical diseases 2015 Jan;9(1):e0003434
Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis.
Xu Y, Dai GJ, Liu Q, Liu ZL, Song ZQ, Li L, Chen WH, Lin N
Experimental and therapeutic medicine 2014 Oct;8(4):1065-1074
Experimental and therapeutic medicine 2014 Oct;8(4):1065-1074
Effect of focal mild hypothermia on expression of MMP-9, TIMP-1, Tau-1 and β-APP in rats with cerebral ischaemia/reperfusion injury.
Zhao JK, Guan FL, Duan SR, Zhao JW, Sun RH, Zhang LM, Wang DS
Brain injury 2013;27(10):1190-8
Brain injury 2013;27(10):1190-8
Anti-fibrotic effects of puerarin on CCl4-induced hepatic fibrosis in rats possibly through the regulation of PPAR-γ expression and inhibition of PI3K/Akt pathway.
Guo C, Xu L, He Q, Liang T, Duan X, Li R
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Jun;56:436-42
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Jun;56:436-42
The effect of 2,3,4',5-tetrahydroxystilbene-2-0-β-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms.
Xu XL, Ling DY, Zhu QY, Fan WJ, Zhang W
European journal of pharmacology 2013 Jan 5;698(1-3):370-8
European journal of pharmacology 2013 Jan 5;698(1-3):370-8
Acipimox attenuates atherosclerosis and enhances plaque stability in ApoE-deficient mice fed a palmitate-rich diet.
Jin F, Jiang S, Yang D, Zhang X, Yang Y, Zhang Y, Li K, Yang Y, Ma S
Biochemical and biophysical research communications 2012 Nov 9;428(1):86-92
Biochemical and biophysical research communications 2012 Nov 9;428(1):86-92
Synthetic gelatinases inhibitor attenuates electromagnetic pulse-induced blood-brain barrier disruption by inhibiting gelatinases-mediated ZO-1 degradation in rats.
Qiu LB, Zhou Y, Wang Q, Yang LL, Liu HQ, Xu SL, Qi YH, Ding GR, Guo GZ
Toxicology 2011 Jul 11;285(1-2):31-8
Toxicology 2011 Jul 11;285(1-2):31-8
Noninvasive limb ischemic preconditioning protects against myocardial I/R injury in rats.
Li SJ, Wu YN, Kang Y, Yin YQ, Gao WZ, Liu YX, Lou JS
The Journal of surgical research 2010 Nov;164(1):162-8
The Journal of surgical research 2010 Nov;164(1):162-8
Inhibition effect of Guizhi-Fuling-decoction on the invasion of human cervical cancer.
Yao Z, Shulan Z
Journal of ethnopharmacology 2008 Oct 30;120(1):25-35
Journal of ethnopharmacology 2008 Oct 30;120(1):25-35
Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats.
Yang Q, Xie RJ, Geng XX, Luo XH, Han B, Cheng ML
World journal of gastroenterology 2005 Aug 28;11(32):4953-6
World journal of gastroenterology 2005 Aug 28;11(32):4953-6
Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis.
Li Q, Liu DW, Zhang LM, Zhu B, He YT, Xiao YH
World journal of gastroenterology 2005 Apr 28;11(16):2438-43
World journal of gastroenterology 2005 Apr 28;11(16):2438-43
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-TIMP-1 antibody, PA1385, IHC(P)IHC(P): Human Mammary Cancer Tissue
- Additional image
