Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 17278-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17278-1-AP, RRID:AB_2211001
- Product name
- UBE2L6 antibody
- Antibody type
- Polyclonal
- Description
- UBE2L6 antibody (Cat. #17278-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ISG15 deficiency in hepatic stellate cells promotes TGFβ2-induced liver fibrosis by counteracting CREB1 ISGylation.
Porcine reproductive and respiratory syndrome virus NSP5 exploited UBE2L6 to promote viral replication via antagonising host RLRs and ISGylation.
Decursin induces FLT3-ITD acute myeloid leukemia cell apoptosis by increasing the expression of the ubiquitin-conjugase UBE2L6.
Machine Learning Screening and Validation of PANoptosis-Related Gene Signatures in Sepsis.
p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6.
The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells.
Association of UBE2L6 and ABCB6 Expression With Platinum Resistance in Serous Ovarian Carcinoma.
High VHL Expression Reverses Warburg Phenotype and Enhances Immunogenicity in Kidney Tumor Cells.
Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting.
Yuan Y, Li J, Rao D, Lu X, Chen M, Chen X, Long X, Zhang B, Liang H, Chen Q, Zhao J
Gut 2026 May 12;75(6):1186-1200
Gut 2026 May 12;75(6):1186-1200
Porcine reproductive and respiratory syndrome virus NSP5 exploited UBE2L6 to promote viral replication via antagonising host RLRs and ISGylation.
Zhu Z, Chen L, Zhang M, Lin Q, Yan Y, Wang W, Wen W, Zhang Z, Li X
Veterinary research 2025 Jul 3;56(1):136
Veterinary research 2025 Jul 3;56(1):136
Decursin induces FLT3-ITD acute myeloid leukemia cell apoptosis by increasing the expression of the ubiquitin-conjugase UBE2L6.
Zhang T, Li Y, Liao W, Mou Y, Zhan X, Hu Q, Zhao Z, Xiong D
Cell communication and signaling : CCS 2025 Apr 2;23(1):162
Cell communication and signaling : CCS 2025 Apr 2;23(1):162
Machine Learning Screening and Validation of PANoptosis-Related Gene Signatures in Sepsis.
Xu J, Zhu M, Luo P, Gong Y
Journal of inflammation research 2024;17:4765-4780
Journal of inflammation research 2024;17:4765-4780
p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6.
Cheng Y, Zhang M, Xu R, Fu L, Xue M, Xu C, Tang C, Fang T, Liu X, Sun B, Chen L
Experimental gerontology 2024 Apr;188:112391
Experimental gerontology 2024 Apr;188:112391
The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells.
Noyes C, Kitajima S, Li F, Suita Y, Miriyala S, Isaac S, Ahsan N, Knelson E, Vajdi A, Tani T, Thai TC, Xu D, Murai J, Tapinos N, Takahashi C, Barbie DA, Yajima M
Communications biology 2023 Jan 18;6(1):65
Communications biology 2023 Jan 18;6(1):65
Association of UBE2L6 and ABCB6 Expression With Platinum Resistance in Serous Ovarian Carcinoma.
Shibahara M, Kurita T, Murakami M, Harada H, Koi C, Izumi H, Yoshino K
Anticancer research 2023 Aug;43(8):3787-3792
Anticancer research 2023 Aug;43(8):3787-3792
High VHL Expression Reverses Warburg Phenotype and Enhances Immunogenicity in Kidney Tumor Cells.
Zhu S, Ding W, Chen Y, Wang W, Xu R, Liu C, Liu X, Deng H
Genomics, proteomics & bioinformatics 2022 Aug;20(4):657-669
Genomics, proteomics & bioinformatics 2022 Aug;20(4):657-669
Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting.
Jin J, Meng X, Huo Y, Deng H
Cell death & disease 2021 Jul 13;12(7):697
Cell death & disease 2021 Jul 13;12(7):697
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17278-1-AP(UBE2L6 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of Hela cells, using UBE2L6 antibody 17278-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line