Antibody data
- Antibody Data
- Antigen structure
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- Product number
- NB100-64677 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-64677, RRID:AB_963442
- Product name
- Mouse Monoclonal Properdin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. NB100-64677 recognizes human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. NB100-64677 does not inhibit function of complement factor P.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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