DPABH-03423

antibody from Creative Diagnostics

Targeting: PRMT5 HRMT1L5, SKB1, SKB1Hs

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-03423

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-03423, RRID:AB_2520309

Product name

Rabbit Anti-Human PRMT5 Polyclonal antibody

Antibody type

Polyclonal

Description

PRMT5 is a Type II enzyme that catalyzes arginine monomethylation and symmetric dimethylation (Rme1 and Rme2s). The many targets of PRMT5 include ribosomal proteins, the histone chaperone nucleoplasmin, p53, and histones. PRMT5 is frequently observed in a complex with the cofactor, methylosome protein 50 (MEP50), which is required for PRMT5 activity. PRMT5 is upregulated in several human malignancies, including lymphomas, lung cancer, breast cancer and colorectal cancer.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL