ABIN356529

antibody from antibodies-online

Targeting: PRMT5 HRMT1L5, SKB1, SKB1Hs

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN356529

Provider

antibodies-online

Product name

anti-Protein Arginine Methyltransferase 5 (PRMT5) (C-Term) antibody

Antibody type

Polyclonal

Description

Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.

Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, Kumar J, Tempst P, Sif S
Molecular and cellular biology 2003 Nov;23(21):7475-87

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Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family.

Rho J, Choi S, Seong YR, Cho WK, Kim SH, Im DS
The Journal of biological chemistry 2001 Apr 6;276(14):11393-401

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The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.

Pollack BP, Kotenko SV, He W, Izotova LS, Barnoski BL, Pestka S
The Journal of biological chemistry 1999 Oct 29;274(44):31531-42

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Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs.

Gilbreth M, Yang P, Bartholomeusz G, Pimental RA, Kansra S, Gadiraju R, Marcus S
Proceedings of the National Academy of Sciences of the United States of America 1998 Dec 8;95(25):14781-6