ABIN261682

antibody from antibodies-online

Targeting: KDM4B JMJD2B, KIAA0876, TDRD14B

Western blot (Supportive data in Antibodypedia)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ABIN261682

Provider

antibodies-online

Product name

anti-Lysine (K)-Specific Demethylase 4B (KDM4B) (AA 1056-1096) antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 1056-1096

Isotype

IgG

Vial size

100 μL

Storage

Store at 4°C. Do not freeze.

Handling

Do not freeze.

References

Submitted references

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.

Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S
The EMBO journal 2012 Apr 18;31(8):1865-78

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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.

Toyokawa G, Cho HS, Iwai Y, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Shimizu N, Tanaka H, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R
Cancer prevention research (Philadelphia, Pa.) 2011 Dec;4(12):2051-61

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The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.

Beyer S, Kristensen MM, Jensen KS, Johansen JV, Staller P
The Journal of biological chemistry 2008 Dec 26;283(52):36542-52

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB