Antibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [3]
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- Product number
- ABIN261682 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Lysine (K)-Specific Demethylase 4B (KDM4B) (AA 1056-1096) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 1056-1096
- Isotype
- IgG
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.
The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.
Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S
The EMBO journal 2012 Apr 18;31(8):1865-78
The EMBO journal 2012 Apr 18;31(8):1865-78
The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Toyokawa G, Cho HS, Iwai Y, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Shimizu N, Tanaka H, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R
Cancer prevention research (Philadelphia, Pa.) 2011 Dec;4(12):2051-61
Cancer prevention research (Philadelphia, Pa.) 2011 Dec;4(12):2051-61
The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.
Beyer S, Kristensen MM, Jensen KS, Johansen JV, Staller P
The Journal of biological chemistry 2008 Dec 26;283(52):36542-52
The Journal of biological chemistry 2008 Dec 26;283(52):36542-52
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB