Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 24474-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- C1QBP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated C1QBP antibody (Cat. #24474-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prophylactic PDE4 and PDE4B inhibition reduce lesion size and neutrophil infiltration following ischemic stroke in male mice.
Identification of a stromal immunosuppressive barrier orchestrated by SPP1(+)/C1QC(+) macrophages and CD8(+) exhausted T cells driving gastric cancer immunotherapy resistance.
HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.
Obesity induced by a high-fat diet regulates the MYC‒PPIL1 network in the mediation of asthenozoospermia.
C1QBP forms a positive feedback loop with the PAICS/FAK/C-MYC axis to promote cancer cell proliferation.
Cyclophilin D reduces Ca2+ sequestration by complement 1q binding protein.
The pUL47 tegument protein of Marek's Disease Virus interacts with p32/C1QBP to promote horizontal transmission.
Exploring the therapeutic effects and molecular mechanisms of total flavonoids of Abelmoschus manihot (L.) Medic in the treatment of IgA nephropathy based on WGCNA.
Identification of feature genes in intestinal epithelial cell types.
Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis.
Ultrasound molecular imaging of p32 protein translocation for evaluation of tumor metastasis.
A nucleolar long "non-coding" RNA encodes a novel protein that functions in response to stress.
C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.
Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
PSMA-targeted nanoparticles for specific penetration of blood-brain tumor barrier and combined therapy of brain metastases.
Cerebral Immunohistochemical Characterization of the H(2)S and the Oxytocin Systems in a Porcine Model of Acute Subdural Hematoma.
The Expression Pattern of p32 in Sheep Muscle and Its Role in Differentiation, Cell Proliferation, and Apoptosis of Myoblasts.
Proteomic Analysis Reveals the Renoprotective Effect of Tribulus terrestris against Obesity-Related Glomerulopathy in Rats.
Ponsaerts L, Alders L, Schepers M, Kemps H, Pirlet E, Willems E, De Bondt M, Jacobs R, Brullo C, Bruno O, Fedele E, Ricciarelli R, Prickaerts J, Somers V, Vandenbosch M, Vanmierlo T, Bronckaers A
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Apr;46(4):896-912
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Apr;46(4):896-912
Identification of a stromal immunosuppressive barrier orchestrated by SPP1(+)/C1QC(+) macrophages and CD8(+) exhausted T cells driving gastric cancer immunotherapy resistance.
Ma G, Liu X, Jiang Q, Li S, Wu Q, Liang B, Sun F, Gu C, Liao W, Zhang Z, Shi M, Huang Q
Frontiers in immunology 2025;16:1618591
Frontiers in immunology 2025;16:1618591
HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.
Li H, Cai S, Mu H, Chang T, Wang X, Tang T, Dong T, Zhang Y, Zhang L, Li H, Zhou L, Xiang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03828
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03828
Obesity induced by a high-fat diet regulates the MYC‒PPIL1 network in the mediation of asthenozoospermia.
Shi M, Xu L, Zheng W, Lin X, Qin G
Basic and clinical andrology 2025 Oct 10;35(1):38
Basic and clinical andrology 2025 Oct 10;35(1):38
C1QBP forms a positive feedback loop with the PAICS/FAK/C-MYC axis to promote cancer cell proliferation.
Cheng X, Wang M, Li W, Tian B, Zhang J, Zhang C, Liu P
Oncogene 2025 Nov;44(45):4363-4376
Oncogene 2025 Nov;44(45):4363-4376
Cyclophilin D reduces Ca2+ sequestration by complement 1q binding protein.
Adegbite O, Adegbite Y, Pickering C, Criddle DN, Lian LY
The Biochemical journal 2025 Dec 16;482(24):1919-34
The Biochemical journal 2025 Dec 16;482(24):1919-34
The pUL47 tegument protein of Marek's Disease Virus interacts with p32/C1QBP to promote horizontal transmission.
Durand M, Chuard A, Rémy S, Courvoisier-Guyader K, Leclercq S, Pichon J, Denesvre C, Pasdeloup D
PLoS pathogens 2025 Aug;21(8):e1013434
PLoS pathogens 2025 Aug;21(8):e1013434
Exploring the therapeutic effects and molecular mechanisms of total flavonoids of Abelmoschus manihot (L.) Medic in the treatment of IgA nephropathy based on WGCNA.
Wen C, Su H, Li J, Zou J, Gong M, Wang F, Ge H
Journal of ethnopharmacology 2025 Aug 29;352:120191
Journal of ethnopharmacology 2025 Aug 29;352:120191
Identification of feature genes in intestinal epithelial cell types.
Lou R, Song W, Yu S, Wang X, Liu Y, Chen YG, Wang Y
Cell regeneration (London, England) 2024 Nov 15;13(1):24
Cell regeneration (London, England) 2024 Nov 15;13(1):24
Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis.
Chandran RR, Vijayaraj P, Garcia-Milian R, King J, Castillo K, Chen L, Kwon Y, William S, Rickabaugh TM, Langerman J, Choi W, Sen C, Lever JEP, Li Q, Pavelkova N, Plosa EJ, Rowe SM, Plath K, Clair G, Gomperts BN
bioRxiv : the preprint server for biology 2024 Jun 22;
bioRxiv : the preprint server for biology 2024 Jun 22;
Ultrasound molecular imaging of p32 protein translocation for evaluation of tumor metastasis.
Hao Y, Luo J, Wang Y, Li Z, Wang X, Yan F
Biomaterials 2023 Feb;293:121974
Biomaterials 2023 Feb;293:121974
A nucleolar long "non-coding" RNA encodes a novel protein that functions in response to stress.
Feng S, Desotell A, Ross A, Jovanovic M, Manley JL
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 28;120(9):e2221109120
Proceedings of the National Academy of Sciences of the United States of America 2023 Feb 28;120(9):e2221109120
C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.
Yang LX, Zhang CT, Yang MY, Zhang XH, Liu HC, Luo CH, Jiang Y, Wang ZM, Yang ZY, Shi ZP, Yang YC, Wei RQ, Zhou L, Mi J, Zhou AW, Yao ZR, Xia L, Yan JS, Lu Y
Blood 2023 Feb 16;141(7):766-786
Blood 2023 Feb 16;141(7):766-786
Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
Tian H, Wang G, Wang Q, Zhang B, Jiang G, Li H, Chai D, Fang L, Wang M, Zheng J
Cancer science 2022 Mar;113(3):875-890
Cancer science 2022 Mar;113(3):875-890
PSMA-targeted nanoparticles for specific penetration of blood-brain tumor barrier and combined therapy of brain metastases.
Ni J, Miao T, Su M, Khan NU, Ju X, Chen H, Liu F, Han L
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:934-947
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:934-947
Cerebral Immunohistochemical Characterization of the H(2)S and the Oxytocin Systems in a Porcine Model of Acute Subdural Hematoma.
Denoix N, Merz T, Unmuth S, Hoffmann A, Nespoli E, Scheuerle A, Huber-Lang M, Gündel H, Waller C, Radermacher P, McCook O
Frontiers in neurology 2020;11:649
Frontiers in neurology 2020;11:649
The Expression Pattern of p32 in Sheep Muscle and Its Role in Differentiation, Cell Proliferation, and Apoptosis of Myoblasts.
Ma J, Ren C, Yang H, Zhao J, Wang F, Wan Y
International journal of molecular sciences 2019 Oct 18;20(20)
International journal of molecular sciences 2019 Oct 18;20(20)
Proteomic Analysis Reveals the Renoprotective Effect of Tribulus terrestris against Obesity-Related Glomerulopathy in Rats.
Jiang YH, Jiang LY, Wu S, Jiang WJ, Xie L, Li W, Yang CH
Biological & pharmaceutical bulletin 2018 Sep 1;41(9):1430-1439
Biological & pharmaceutical bulletin 2018 Sep 1;41(9):1430-1439
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 24474-1-AP( C1QBP Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The C1QBP antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human C1QBP. This antibody recognizes human, mouse antigen. The C1QBP antibody has been validated for the following applications: ELISA, WB, IHC analysis.