BS60527

antibody from Bioworld Technology, Inc
Targeting: TNFRSF17 BCM, BCMA, CD269, TNFRSF13A
Provider product page for BS60527

Antibody data

Product number
BS60527 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TNFRSF17 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human TNFRSF17
Description
The B cell maturation protein (BCMA), also designated BCM and tumor necrosis factor receptor superfamily, member 17, is a type I integral membrane protein located on chromosome band 16p13.1 that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TNFRSF17 protein structure - BS60527 shown in red.