BS8893

antibody from Bioworld Technology, Inc
Targeting: GSDME DFNA5, ICERE-1
Provider product page for BS8893
Western blot
Immunohistochemistry

Antibody data

Product number
BS8893 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DFNA5 polyclonal antibody
Antibody type
Polyclonal
Antigen
Non-syndromic hearing impairment protein 5; Inversely correlated with estrogen receptor expression 1; ICERE-1; ICERE1
Description
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas as two alternatively spliced isoforms, designated short and long. Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain. The gene encoding DFNA5 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GSDME protein structure - BS8893 shown in red.