67731-1-Ig

antibody from Proteintech Group

Targeting: GSDME DFNA5, ICERE-1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

67731-1-Ig

Provider

Proteintech Group

Product name

DFNA5/GSDME antibody

Antibody type

Monoclonal

Description

DFNA5/GSDME antibody (Cat. #67731-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat, pig and has been validated for the following applications: WB, ELISA.

Reactivity

Human, Mouse, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1D9C3

Vial size

20ul, 150ul

References

Submitted references

IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.

Ren T, Chen X, Wang X, Xu Y, Shao N
Journal of experimental & clinical cancer research : CR 2026 Feb 16;45(1)

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Tubastatin A alleviates post-resuscitation myocardial damage possibly via inhibiting GSDME-mediated pyroptosis and MLKL-mediated necroptosis in a porcine model of cardiac arrest.

Lai L, Fang Y, Xie L, Zhao X, Xu J, Lan P
Resuscitation plus 2025 Nov;26:101158

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Protection against post-resuscitation renal injury by Artesunate via inhibition of caspase-3/Gasdermin E -mediated pyroptosis.

Wang Q, Shen P, Wu W, Zhu J, Xu J
Resuscitation plus 2025 Nov;26:101138

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Comprehensive analysis, diagnosis, prognosis, and cordycepin (CD) regulations for GSDME expressions in pan-cancers.

Fu J, Li D, Zhang L, Maghsoudloo M, Cheng J, Fu J
Cancer cell international 2024 Aug 8;24(1):279

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SNAP25 ameliorates postoperative cognitive dysfunction by facilitating PINK1-dependent mitophagy and impeding caspase-3/GSDME-dependent pyroptosis.

Wang W, Gao W, Zhang L, Xia Z, Zhao B
Experimental neurology 2023 Sep;367:114463

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Mitochondria-Targeting Pyroptosis Amplifier of Lonidamine-Modified Black Phosphorus Nanosheets for Glioblastoma Treatments.

Ye Y, Ren K, Dong Y, Yang L, Zhang D, Yuan Z, Ma N, Song Y, Huang X, Qiao H
ACS applied materials & interfaces 2023 Jun 7;15(22):26285-26297

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Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.

Wang W, Zhao B, Gao W, Song W, Hou J, Zhang L, Xia Z
ACS chemical neuroscience 2023 Apr 5;14(7):1249-1260