Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB532A-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse TGF-beta RII APC-conjugated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse TGF-beta RII in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) TGF-beta RII is observed and less than 1% cross-reactivity with recombinant mouse TGF-beta RI and rhTGF-beta RIII is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Red dye
- Antigen sequence
Q62312
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling.
MicroRNAs are implicated in the suppression of CD4+CD25− conventional T cell proliferation by CD4+CD25+ regulatory T cells.
TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses.
Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
Ansa-Addo EA, Zhang Y, Yang Y, Hussey GS, Howley BV, Salem M, Riesenberg B, Sun S, Rockey DC, Karvar S, Howe PH, Liu B, Li Z
The Journal of clinical investigation 2017 Apr 3;127(4):1321-1337
The Journal of clinical investigation 2017 Apr 3;127(4):1321-1337
MicroRNAs are implicated in the suppression of CD4+CD25− conventional T cell proliferation by CD4+CD25+ regulatory T cells.
Zhou S, Dong X, Zhang C, Chen X, Zhu J, Li W, Song X, Xu Z, Zhang W, Yang X, Li Y, Liu F, Sun C
Molecular immunology 2015 Feb;63(2):464-72
Molecular immunology 2015 Feb;63(2):464-72
TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses.
Okamura T, Sumitomo S, Morita K, Iwasaki Y, Inoue M, Nakachi S, Komai T, Shoda H, Miyazaki J, Fujio K, Yamamoto K
Nature communications 2015 Feb 19;6:6329
Nature communications 2015 Feb 19;6:6329
Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC
The Journal of clinical investigation 2014 Jan;124(1):448-60
The Journal of clinical investigation 2014 Jan;124(1):448-60
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII APC-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB532A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.