HPAB-0232-YC

antibody from Creative Biolabs

Targeting: TGFBR2 MFS2, TBR-ii, TBRII

No application information provided.

Antibody Data

Product number

HPAB-0232-YC

Provider

Creative Biolabs

Product name

Human Anti-TGFBR2 Recombinant Antibody (clone TGF1)

Antibody type

Monoclonal

Description

Provided are novel isolated anti-TGFPRII mAbs. The antibody are capable of the following activities: displaying high affinity binding toward the extracellular domain of human TGFPRII; blocking the binding of TGORII ligands (TGF131, TGO2, and TGO3) to TGFf3RII, thereby inhibiting TGFf3-induced Smad2 phosphorylation; internalizing TGORII, which can act as a signaling down-regulation mechanism independent of ligand-receptor interaction; inhibiting ligand-induced TGORII signaling pathways and inhibiting TGORII-mediated cellular activities.

Reactivity

Human

Antibody clone number

TGF1

Storage

Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.