Antibody data
- Antibody Data
- Antigen structure
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- Product number
- HPAB-0232-YC-F(E) - Provider product page
- Provider
- Creative Biolabs
- Product name
- Human Anti-TGFBR2 Recombinant Antibody (clone TGF1); Fab Fragment
- Antibody type
- Monoclonal
- Description
- Provided are novel isolated anti-TGFPRII mAbs. The antibody are capable of the following activities: displaying high affinity binding toward the extracellular domain of human TGFPRII; blocking the binding of TGORII ligands (TGF131, TGO2, and TGO3) to TGFf3RII, thereby inhibiting TGFf3-induced Smad2 phosphorylation; internalizing TGORII, which can act as a signaling down-regulation mechanism independent of ligand-receptor interaction; inhibiting ligand-induced TGORII signaling pathways and inhibiting TGORII-mediated cellular activities.
- Reactivity
- Human
- Host
- Human
- Antibody clone number
- TGF1
- Storage
- Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.
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