BAF241

antibody from R&D Systems

Targeting: TGFBR2 MFS2, TBR-ii, TBRII

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

BAF241

Provider

R&D Systems

Product name

Human TGF-beta RII Biotinylated Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human TGF-beta RII in ELISAs and Western blots. In sandwich immunoassays, approximately 25% cross-reactivity with recombinant human (rh) TGF-beta RIIb is observed and less than 0.05% cross-reactivity with rhTGF-beta RI, rhTGF-beta RIII, recombinant mouse TGF-beta RII, and rhTGF-beta 1 is observed.

Reactivity

Human

Host

Goat

Conjugate

Biotin

Antigen sequence

P37173


Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases.

Xu W, Zhang Z, Yang Y, Hu Z, Wang CH, Morgan M, Wu Y, Hutten R, Xiao X, Stock S, Guise T, Prabhakar BS, Brendler C, Seth P
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Aug;22(8):1504-1517

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Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.

La Cava A, Ebling FM, Hahn BH
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 1;173(5):3542-8

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Ig-reactive CD4+CD25+ T cells from tolerized (New Zealand Black x New Zealand White)F1 mice suppress in vitro production of antibodies to DNA.

La Cava A, Ebling FM, Hahn BH
Journal of immunology (Baltimore, Md. : 1950) 2004 Sep 1;173(5):3542-8