Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 25250-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CHL1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CHL1 antibody (Cat. #25250-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, monkey and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Overexpression of close homolog of L1 enhances the chemosensitivity of lung cancer cells via inhibition of the Akt pathway.
Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans.
Bao M, Li S, Zhu Y, Dong X, Wang R, Jing F
Experimental and therapeutic medicine 2024 Apr;27(4):165
Experimental and therapeutic medicine 2024 Apr;27(4):165
Overexpression of close homolog of L1 enhances the chemosensitivity of lung cancer cells via inhibition of the Akt pathway.
Cai X, Hu B, Liu S, Liu M, Huang Y, Lei P, Zhang Z, He Z, Zhang L, Huang R
Oncology letters 2020 Oct;20(4):111
Oncology letters 2020 Oct;20(4):111
Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans.
Simoes S, Neufeld JL, Triana-Baltzer G, Moughadam S, Chen EI, Kothiya M, Qureshi YH, Patel V, Honig LS, Kolb H, Small SA
Science translational medicine 2020 Nov 25;12(571)
Science translational medicine 2020 Nov 25;12(571)
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The CHL1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CHL1. This antibody recognizes human, mouse antigen. The CHL1 antibody has been validated for the following applications: ELISA, WB analysis.