Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 339919 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#339919, RRID:AB_2562836
- Product name
- Purified anti-human CD161 (MaxPar® Ready)
- Antibody type
- Monoclonal
- Antigen
- Human NK cells
- Description
- CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- HP-3G10
- Vial size
- 100 µg
- Concentration
- 1 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human PBMCs stained with 145Nd-anti-CD4 (RPA-T4) and 159Tb-anti-CD161 (HP-3G10). Lymphocytes are displayed in the analysis.
- Conjugate
- Unconjugated