Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B12191 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Human anti-Human PTPRJ recombinant monoclonal antibody, clone SFB305 [FITC]
- Antibody type
- Monoclonal
- Description
- It recognozes CD148, a receptor type protein tyrosine phosphatase (PTP) belonging to the type III family of PTPs. CD148 is characterized by an extracellular domain with eight fibronectin type III repeats, a trans-membrane region, and a single cytosolic catalytic domain. Expression of CD148 is found on mature thymocytes, peripheral T cells, B cells, NK cells, granulocytes, macrophages, DC subpopulations, epithelial and endothelial cells, and fibroblasts. An upregulated expression of CD148 on human peripheral T cells is observed upon TCR stimulation. CD148 via regulating the phosphorylation status of substrates such as PDGFR, p120 catenin (CTND1), and SRC kinase, plays vital role in many cellular functions. Additional information: It displays negligible binding to Fc receptors.
- Reactivity
- Human
- Host
- Human
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- SFB305
- Vial size
- for 100 tests
- Storage
- Store protected from light at 2ÿ8 °C. Do not freeze.
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