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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Western blot [2]
- ELISA [2]
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- Product number
- H00009214-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00009214-M01, RRID:AB_538706
- Product name
- Mouse Monoclonal FAIM3 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. FAIM3 - Fas apoptotic inhibitory molecule 3
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Glycan-independent binding and internalization of human IgM to FCMR, its cognate cellular receptor.
IgM and IgA rheumatoid factors purified from rheumatoid arthritis sera boost the Fc receptor- and complement-dependent effector functions of the disease-specific anti-citrullinated protein autoantibodies.
Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells.
Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia.
SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL.
Lloyd KA, Wang J, Urban BC, Czajkowsky DM, Pleass RJ
Scientific reports 2017 Feb 23;7:42989
Scientific reports 2017 Feb 23;7:42989
IgM and IgA rheumatoid factors purified from rheumatoid arthritis sera boost the Fc receptor- and complement-dependent effector functions of the disease-specific anti-citrullinated protein autoantibodies.
Anquetil F, Clavel C, Offer G, Serre G, Sebbag M
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3664-74
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3664-74
Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells.
Murakami Y, Narayanan S, Su S, Childs R, Krzewski K, Borrego F, Weck J, Coligan JE
Journal of immunology (Baltimore, Md. : 1950) 2012 Jul 15;189(2):587-97
Journal of immunology (Baltimore, Md. : 1950) 2012 Jul 15;189(2):587-97
Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia.
Li FJ, Kubagawa Y, McCollum MK, Wilson L, Motohashi T, Bertoli LF, Barton JC, Barnes S, Davis RS, Kubagawa H
Blood 2011 Nov 3;118(18):4902-9
Blood 2011 Nov 3;118(18):4902-9
SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL.
Proto-Siqueira R, Panepucci RA, Careta FP, Lee A, Clear A, Morris K, Owen C, Rizzatti EG, Silva WA Jr, Falcão RP, Zago MA, Gribben JG
Blood 2008 Jul 15;112(2):394-7
Blood 2008 Jul 15;112(2):394-7
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: FAIM3 Antibody (1E4) [H00009214-M01] - Analysis of FAIM3 expression in transfected 293T cell line by FAIM3 monoclonal antibody (M01), clone 1E4.Lane 1: FAIM3 transfected lysate(43.1 KDa).Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: FAIM3 Antibody (1E4) [H00009214-M01] - FAIM3 monoclonal antibody (M01), clone 1E4 Analysis of FAIM3 expression in K-562.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: FAIM3 Antibody (1E4) [H00009214-M01] - ELISA analysis of FAIM3 in PBMC CD14 negative fraction. Image courtesy of anonymous customer product review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: FAIM3 Antibody (1E4) [H00009214-M01] - Detection limit for recombinant GST tagged FAIM3 is approximately 0.03ng/ml as a capture antibody.
