APR02365G

antibody from Leading Biology
Targeting: FCMR FAIM3, TOSO
Provider product page for APR02365G
Western blot
Immunohistochemistry

Antibody data

Product number
APR02365G - Provider product page
Provider
Leading Biology
Product name
FCMR / FAIM3 Antibody (C-Terminus)
Antibody type
Polyclonal
Description
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Reactivity
Human
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
FCMR protein structure - APR02365G shown in red.