BS3123
KDELR2 antibody from Bioworld Technology, Inc
ELP-1, ERD2.2
- Western blot
Supportive data in Antibodypedia
- Immunocytochemistry
Data presented on provider website
- Immunohistochemistry
Data presented on provider website
Antibody data
- Antibody Data
- Knockdown Reagents [0]
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS3123
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS3123, RRID:AB_1914366
- Product name
- KDEL Receptor 2 (L119) polyclonal antibody
- Provider product page
- Bioworld Technology, Inc - BS3123
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 100-150 of Human KDEL Receptor 2.
- Description
- Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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