Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 10574-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10574-1-AP, RRID:AB_2196710
- Product name
- SUV39H1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SUV39H1 antibody (Cat. #10574-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma.
ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.
SUV39H1 Inhibits Angiogenesis in Limb Ischemia of Mice.
Dependence of glucose transport on autophagy and GAPDH activity.
N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma.
Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.
Class II transactivator (CIITA) mediates IFN-γ induced eNOS repression by enlisting SUV39H1.
Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation.
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression.
Chen Y, Weng X, Zhang C, Wang S, Wu X, Cheng B
PeerJ 2024;12:e17222
PeerJ 2024;12:e17222
ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.
Xu H, Akinyemi IA, Haley J, McIntosh MT, Bhaduri-McIntosh S
Nucleic acids research 2023 Nov 10;51(20):11104-11122
Nucleic acids research 2023 Nov 10;51(20):11104-11122
SUV39H1 Inhibits Angiogenesis in Limb Ischemia of Mice.
Niu W, Cao W, Wu F, Liang C
Cell transplantation 2023 Jan-Dec;32:9636897231198167
Cell transplantation 2023 Jan-Dec;32:9636897231198167
Dependence of glucose transport on autophagy and GAPDH activity.
Craven RJ, Frazier HN, Thibault O
Brain research 2022 Feb 1;1776:147747
Brain research 2022 Feb 1;1776:147747
N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.
Zhao Y, Huang S, Tan X, Long L, He Q, Liang X, Bai J, Li Q, Lin J, Li Y, Liu N, Ma J, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(36):e2205091
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(36):e2205091
Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Journal of medicinal chemistry 2022 Aug 25;65(16):11010-11033
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM
iScience 2022 Apr 15;25(4):104162
iScience 2022 Apr 15;25(4):104162
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Li J, Shao W, Zhao J
Human cell 2021 Mar;34(2):570-578
Human cell 2021 Mar;34(2):570-578
CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma.
Qi Y, Wang D, Huang W, Wang B, Huang D, Xiong F, Chen X, Chen Y
Journal of experimental & clinical cancer research : CR 2019 Oct 7;38(1):413
Journal of experimental & clinical cancer research : CR 2019 Oct 7;38(1):413
Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.
Wang Y, Zhang J, Ren S, Sun D, Huang HY, Wang H, Jin Y, Li F, Zheng C, Yang L, Deng L, Jiang Z, Jiang T, Han X, Hou S, Guo C, Li F, Gao D, Qin J, Gao D, Chen L, Lin SH, Wong KK, Li C, Hu L, Zhou C, Ji H
Cell reports 2019 Jul 9;28(2):512-525.e6
Cell reports 2019 Jul 9;28(2):512-525.e6
Class II transactivator (CIITA) mediates IFN-γ induced eNOS repression by enlisting SUV39H1.
Weng X, Zhang Y, Li Z, Yu L, Xu F, Fang M, Hou L, Ge J, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Feb;1862(2):163-172
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Feb;1862(2):163-172
Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation.
Tamgue O, Lei M
Asian Pacific journal of cancer prevention : APJCP 2017 Sep 27;18(9):2519-2526
Asian Pacific journal of cancer prevention : APJCP 2017 Sep 27;18(9):2519-2526
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
Yang G, Weng X, Zhao Y, Zhang X, Hu Y, Dai X, Liang P, Wang P, Ma L, Sun X, Hou L, Xu H, Fang M, Li Y, Jenuwein T, Xu Y, Sun A
Nature communications 2017 Mar 31;8:14941
Nature communications 2017 Mar 31;8:14941
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Cheng W, Qi Y, Tian L, Wang B, Huang W, Chen Y
Cell death & disease 2017 Feb 23;8(2):e2628
Cell death & disease 2017 Feb 23;8(2):e2628
Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression.
Cheng W, Tian L, Wang B, Qi Y, Huang W, Li H, Chen YJ
Oncotarget 2016 Jul 26;7(30):48107-48119
Oncotarget 2016 Jul 26;7(30):48107-48119
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SUV39H1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SUV39H1. This antibody recognizes human,mouse,rat antigen. The SUV39H1 antibody has been validated for the following applications: ELISA, WB analysis.