orb66954

antibody from Biorbyt
Targeting: CUL4A
Provider product page for orb66954
Western blot

Antibody data

Product number
orb66954 - Provider product page
Provider
Biorbyt
Product name
CUL4A antibody
Antibody type
Polyclonal
Description
Rabbit polyclonal to CUL4A.CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNAdamage-response proteins. CUL4A is a core component of multiple cullin-RING-based E3 ubiquitinproteinligase complexes which mediate the ubiquitination and subsequent proteasomal degradationof target proteins. As a scaffold protein, CUL4A may contribute to catalysis through positioning of thesubstrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complexis dependent on the neddylation of the cullin subunit. CUL4A may be involved in ubiquitination of JUN,P53, CDKN1B and HOXA9.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Vial size
100 ul
Storage
-20°C
CUL4A protein structure - orb66954 shown in red.