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- Antigen structure
- References [3]
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- Product number
- 32-7000 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- MEK7 Monoclonal Antibody (2E3G1)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human, Mouse, Canine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2E3G1
- Vial size
- 100 µg
- Concentration
- 0.5 mg/mL
- Storage
- -20°C
Submitted references Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A.
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.
Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).
Oben KZ, Alhakeem SS, McKenna MK, Brandon JA, Mani R, Noothi SK, Jinpeng L, Akunuru S, Dhar SK, Singh IP, Liang Y, Wang C, Abdel-Latif A, Stills HF Jr, St Clair DK, Geiger H, Muthusamy N, Tohyama K, Gupta RC, Bondada S
Oncotarget 2017 Sep 29;8(44):77436-77452
Oncotarget 2017 Sep 29;8(44):77436-77452
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.
Brumby AM, Goulding KR, Schlosser T, Loi S, Galea R, Khoo P, Bolden JE, Aigaki T, Humbert PO, Richardson HE
Genetics 2011 May;188(1):105-25
Genetics 2011 May;188(1):105-25
Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).
Kelkar N, Delmotte MH, Weston CR, Barrett T, Sheppard BJ, Flavell RA, Davis RJ
Proceedings of the National Academy of Sciences of the United States of America 2003 Aug 19;100(17):9843-8
Proceedings of the National Academy of Sciences of the United States of America 2003 Aug 19;100(17):9843-8
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- Figure 5 JNK/AP-1 signaling is activated in WFA-treated MDS-L cells (A) Phospho and total protein immunoblots for MKK7, JNK and C-JUN in WFA-treated (10 muM) MDS-L cells for the indicated time-points. Activated protein expression levels normalized to the respective total protein are presented. Data are representative of at least two independent experiments. (B) MDS-L cells co-transfected with either an AP-1 or empty firefly luciferase expression vector and a renilla luciferase vector under the control of a constitutive promoter (2:1) were treated with WFA (10 muM) or PMA (30 ng/ml) for 12 h and promoter activity was assessed by the dual Glo luciferase assay. Firefly luciferase activity relative to renilla luciferase activity is shown as mean +- SD of triplicate cultures. Presented data are representative of three independent experiments. (C) BIM ( top ) and p21 ( bottom ) mRNA expression was evaluated by qRT-PCR in MDS-L cells treated with WFA. Gene amplification was normalized to RPII expression and relative amplification was determined by normalizing to DMSO control. ** = p
