Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- AF477 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Neurturin Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human and mouse Neurturin in direct ELISAs and Western blots.
- Reactivity
- Human, Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction.
The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function.
Parasympathetic stimulation improves epithelial organ regeneration.
Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain.
Ferreira JNA, Zheng C, Lombaert IMA, Goldsmith CM, Cotrim AP, Symonds JM, Patel VN, Hoffman MP
Molecular therapy. Methods & clinical development 2018 Jun 15;9:172-180
Molecular therapy. Methods & clinical development 2018 Jun 15;9:172-180
The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function.
Fonseca-Pereira D, Arroz-Madeira S, Rodrigues-Campos M, Barbosa IA, Domingues RG, Bento T, Almeida AR, Ribeiro H, Potocnik AJ, Enomoto H, Veiga-Fernandes H
Nature 2014 Oct 2;514(7520):98-101
Nature 2014 Oct 2;514(7520):98-101
Parasympathetic stimulation improves epithelial organ regeneration.
Knox SM, Lombaert IM, Haddox CL, Abrams SR, Cotrim A, Wilson AJ, Hoffman MP
Nature communications 2013;4:1494
Nature communications 2013;4:1494
Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain.
Hadaczek P, Johnston L, Forsayeth J, Bankiewicz KS
Neuropharmacology 2010 Jun;58(7):1114-21
Neuropharmacology 2010 Jun;58(7):1114-21
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Neurturin in Mouse Embryo. Neurturin was detected in immersion fixed frozen sections of mouse embryo (13 d.p.c.) using Goat Anti-Human/Mouse Neurturin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF477) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to developing muscle cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.