ABIN318699

antibody from antibodies-online

Targeting: SH2B3 IDDM20, LNK

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN318699

Provider

antibodies-online

Product name

anti-SH2B Adaptor Protein 3 (SH2B3) (N-Term) antibody

Antibody type

Polyclonal

Description

Antisera to LNK (NT) were raised by repeated immunisation of Goat with highly purified antigen. Purified IgG prepared by affinity chromatography.

Reactivity

Human

Host

Goat

Epitope

N-Term

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways.

Fitau J, Boulday G, Coulon F, Quillard T, Charreau B
The Journal of biological chemistry 2006 Jul 21;281(29):20148-59

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Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.

Tong W, Lodish HF
The Journal of experimental medicine 2004 Sep 6;200(5):569-80