ABIN513029

antibody from antibodies-online

Targeting: AADAC CES5A1, DAC

Western blot (Recommended by provider)

ELISA (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN513029

Provider

antibodies-online

Product name

anti-Arylacetamide Deacetylase (Esterase) (AADAC) (AA 201-300), (partial) antibody

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

Epitope

AA 201-300, partial

Isotype

IgG

Antibody clone number

2E8

Vial size

100 μg

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Handling

Aliquot to avoid repeated freezing and thawing.

References

Submitted references

N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity.

Muta K, Fukami T, Nakajima M, Yokoi T
Biochemical pharmacology 2014 Jan 15;87(2):352-9

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Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia.

Kobayashi Y, Fukami T, Higuchi R, Nakajima M, Yokoi T
Biochemical pharmacology 2012 Nov 1;84(9):1196-206

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A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity.

Shimizu M, Fukami T, Kobayashi Y, Takamiya M, Aoki Y, Nakajima M, Yokoi T
Drug metabolism and disposition: the biological fate of chemicals 2012 Jun;40(6):1183-90

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Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse.

Kobayashi Y, Fukami T, Nakajima A, Watanabe A, Nakajima M, Yokoi T
Drug metabolism and disposition: the biological fate of chemicals 2012 Apr;40(4):671-9

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Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis.

Watanabe A, Fukami T, Nakajima M, Takamiya M, Aoki Y, Yokoi T
Drug metabolism and disposition: the biological fate of chemicals 2009 Jul;37(7):1513-20

ELISA

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

ELISA