Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx032717 - Provider product page
- Provider
- Abbexa
- Product name
- Protein ENL (MLLT1) Antibody
- Antibody type
- Polyclonal
- Description
- Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t (11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 80 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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