Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS61149 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CA8 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human CA8.
- Description
- Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VIII, also referred to as carbonic anhydrase-related protein VIII (CA-RP VIII), is a member of the carbonic anhydrase family that lacks the Zn-binding motif essential for carbonic anhydrase activity. For this reason, CA VIII does not exhibit catalytic activity but instead may be important in synaptic vesicle formation and transport. In addition, CA VIII may be involved in the invasiveness of non-small cell lung carcinomas and may also play a role in the growth of colon cancer cells.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of CA8 pAb at 1:500 Line1:Mcf-7 whole cell lysateLine2:Line3:sp20 whole cell lysate