Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [31]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 18723-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18723-1-AP, RRID:AB_10603365
- Product name
- GABARAP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GABARAP antibody (Cat. #18723-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy.
Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways.
miR-278-3p targets ATG16L1 to modulate autophagy and suppresses CLas proliferation in Diaphorina citri.
STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders.
Highlighting the hidden: monitoring the avidity-driven association of a fluorescent GABARAP tandem with microtubules in living cells.
Deletion of histamine H2 receptor in VTA dopaminergic neurons of mice induces behavior reminiscent of mania.
Non-lytic spread of poliovirus requires the nonstructural protein 3CD.
A TBK1-independent primordial function of STING in lysosomal biogenesis.
ER-phagy restrains inflammatory responses through its receptor UBAC2.
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy.
Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy.
Cutting Edge: Phagosome-associated Autophagosomes Containing Antigens and Proteasomes Drive TAP-Independent Cross-Presentation.
ATG4B antagonizes antiviral immunity by GABARAP-directed autophagic degradation of TBK1.
Population-based genetic analysis in infertile men reveals novel mutations of ADAD family members in patients with impaired spermatogenesis.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
β-asarone prolongs sleep via regulating the level of glutamate in the PVN.
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis.
PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection.
ATF4 links ER stress with reticulophagy in glioblastoma cells.
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles.
Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.
Protrudin modulates seizure activity through GABA(A) receptor regulation.
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.
The kinesin KIF21B participates in the cell surface delivery of γ2 subunit-containing GABAA receptors.
Defective autophagy and mTORC1 signaling in myotubularin null mice.
Yang J, Dong Y, Xu J, Qian X, Cai Y, Chen Y, Zhang P, Gao D, Cui Z, Cui Y
Developmental cell 2025 Nov 3;60(21):2862-2879.e8
Developmental cell 2025 Nov 3;60(21):2862-2879.e8
Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways.
Kozareva V, Liu Z, Blake K, Qi YA, Rollinson S, Seddighi S, Alsaidi M, Tsitkov S, Prudencio M, Petrucelli L, Dickson DW, Brown AL, Fratta P, Kim HJ, Taylor JP, Ward ME, Fraenkel E, Kargbo-Hill SE
bioRxiv : the preprint server for biology 2025 Nov 1;
bioRxiv : the preprint server for biology 2025 Nov 1;
miR-278-3p targets ATG16L1 to modulate autophagy and suppresses CLas proliferation in Diaphorina citri.
Lu L, Feng Q, Wang S, Ghafar MA, Cheng H, Zhou C, Wang L
International journal of biological macromolecules 2025 May;308(Pt 2):142441
International journal of biological macromolecules 2025 May;308(Pt 2):142441
STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders.
Tang Z, Xing C, Araszkiewicz A, Yang K, Huai W, Jeltema D, Dobbs N, Zhang Y, Sun LO, Yan N
Molecular cell 2025 Apr 17;85(8):1624-1639.e5
Molecular cell 2025 Apr 17;85(8):1624-1639.e5
Highlighting the hidden: monitoring the avidity-driven association of a fluorescent GABARAP tandem with microtubules in living cells.
Üffing A, Gold L, Gensch T, Weiergräber OH, Hoffmann S, Willbold D
Autophagy reports 2024;3(1):2348899
Autophagy reports 2024;3(1):2348899
Deletion of histamine H2 receptor in VTA dopaminergic neurons of mice induces behavior reminiscent of mania.
Ma S, Ma Q, Hu S, Mo X, Zhu C, Zhang X, Jia Z, Tang L, Jiang L, Cui Y, Chen Z, Hu W, Zhang X
Cell reports 2024 Sep 24;43(9):114717
Cell reports 2024 Sep 24;43(9):114717
Non-lytic spread of poliovirus requires the nonstructural protein 3CD.
Aponte-Diaz D, Harris JM, Kang TE, Korboukh V, Sotoudegan MS, Gray JL, Yennawar NH, Moustafa IM, Macadam A, Cameron CE
bioRxiv : the preprint server for biology 2024 Oct 19;
bioRxiv : the preprint server for biology 2024 Oct 19;
A TBK1-independent primordial function of STING in lysosomal biogenesis.
Lv B, Dion WA, Yang H, Xun J, Kim DH, Zhu B, Tan JX
Molecular cell 2024 Oct 17;84(20):3979-3996.e9
Molecular cell 2024 Oct 17;84(20):3979-3996.e9
ER-phagy restrains inflammatory responses through its receptor UBAC2.
He X, He H, Hou Z, Wang Z, Shi Q, Zhou T, Wu Y, Qin Y, Wang J, Cai Z, Cui J, Jin S
The EMBO journal 2024 Nov;43(21):5057-5084
The EMBO journal 2024 Nov;43(21):5057-5084
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy.
Ding SA, Liu H, Zheng R, Ge Y, Fu Z, Mei J, Tang M
Cell biology and toxicology 2024 May 27;40(1):40
Cell biology and toxicology 2024 May 27;40(1):40
Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy.
Knupp J, Chen YJ, Wang E, Arvan P, Tsai B
Cell reports 2024 Aug 27;43(8):114619
Cell reports 2024 Aug 27;43(8):114619
Cutting Edge: Phagosome-associated Autophagosomes Containing Antigens and Proteasomes Drive TAP-Independent Cross-Presentation.
Sengupta D, Galicia-Pereyra R, Han P, Graham M, Liu X, Arshad N, Cresswell P
Journal of immunology (Baltimore, Md. : 1950) 2024 Apr 1;212(7):1063-1068
Journal of immunology (Baltimore, Md. : 1950) 2024 Apr 1;212(7):1063-1068
ATG4B antagonizes antiviral immunity by GABARAP-directed autophagic degradation of TBK1.
Xie W, Zhang C, Wang Z, Chen H, Gu T, Zhou T, Wu Y, Xia F, Li M, Wang J, Jiao R, Cui J, Jin S
Autophagy 2023 Nov;19(11):2853-2868
Autophagy 2023 Nov;19(11):2853-2868
Population-based genetic analysis in infertile men reveals novel mutations of ADAD family members in patients with impaired spermatogenesis.
Dai S, Liu M, Liu M, Jiang C, Yang Y, Han H, Yang Y, Jiang X, Shen Y
Human molecular genetics 2023 May 18;32(11):1814-1825
Human molecular genetics 2023 May 18;32(11):1814-1825
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, Wang X, Xiao F
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
β-asarone prolongs sleep via regulating the level of glutamate in the PVN.
Liu H, Zhou R, Yin L, Si N, Yang C, Huang C, Wang R, Chen X
Biochemical and biophysical research communications 2023 Jul 12;665:71-77
Biochemical and biophysical research communications 2023 Jul 12;665:71-77
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
Zhang G, Jiang C, Yang Y, Wang Y, Zhou H, Dai S, Liu M, Yang Y, Yang L, Shen Q, Zhang T, Zhang X, Yang Y, Shen Y
Cell death and differentiation 2023 Feb;30(2):500-514
Cell death and differentiation 2023 Feb;30(2):500-514
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV Jr
Nature communications 2022 Oct 7;13(1):5924
Nature communications 2022 Oct 7;13(1):5924
ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis.
Zhang J, Wang H, Chen H, Li H, Xu P, Liu B, Zhang Q, Lv C, Song X
Autophagy 2022 Nov;18(11):2636-2655
Autophagy 2022 Nov;18(11):2636-2655
PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection.
Wang S, Guo H, Zhu-Salzman K, Ge F, Sun Y
Nature communications 2022 Feb 11;13(1):846
Nature communications 2022 Feb 11;13(1):846
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Zielke S, Kardo S, Zein L, Mari M, Covarrubias-Pinto A, Kinzler MN, Meyer N, Stolz A, Fulda S, Reggiori F, Kögel D, van Wijk S
Autophagy 2021 Sep;17(9):2432-2448
Autophagy 2021 Sep;17(9):2432-2448
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
Sun L, Wang W, Han C, Huang W, Sun Y, Fang K, Zeng Z, Yang Q, Pan Q, Chen T, Luo X, Chen Y
Molecular cell 2021 Nov 4;81(21):4493-4508.e9
Molecular cell 2021 Nov 4;81(21):4493-4508.e9
The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles.
Sanwald JL, Poschmann G, Stühler K, Behrends C, Hoffmann S, Willbold D
Cells 2020 Jun 16;9(6)
Cells 2020 Jun 16;9(6)
Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.
Lindner P, Christensen SB, Nissen P, Møller JV, Engedal N
Cell communication and signaling : CCS 2020 Jan 27;18(1):12
Cell communication and signaling : CCS 2020 Jan 27;18(1):12
Protrudin modulates seizure activity through GABA(A) receptor regulation.
Lu X, Yang Y, Zhou R, Li Y, Yang Y, Wang X
Cell death & disease 2019 Nov 27;10(12):897
Cell death & disease 2019 Nov 27;10(12):897
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Chen Q, Xiao Y, Chai P, Zheng P, Teng J, Chen J
Current biology : CB 2019 Mar 4;29(5):846-855.e6
Current biology : CB 2019 Mar 4;29(5):846-855.e6
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Skytte Rasmussen M, Mouilleron S, Kumar Shrestha B, Wirth M, Lee R, Bowitz Larsen K, Abudu Princely Y, O'Reilly N, Sjøttem E, Tooze SA, Lamark T, Johansen T
Autophagy 2017 May 4;13(5):834-853
Autophagy 2017 May 4;13(5):834-853
Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.
Boeske A, Schwarten M, Ma P, Tusche M, Mötter J, Möller C, Neudecker P, Hoffmann S, Willbold D
Scientific reports 2017 Jul 20;7(1):5979
Scientific reports 2017 Jul 20;7(1):5979
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.
Chen ZH, Wang WT, Huang W, Fang K, Sun YM, Liu SR, Luo XQ, Chen YQ
Cell death and differentiation 2017 Feb;24(2):212-224
Cell death and differentiation 2017 Feb;24(2):212-224
The kinesin KIF21B participates in the cell surface delivery of γ2 subunit-containing GABAA receptors.
Labonté D, Thies E, Kneussel M
European journal of cell biology 2014 Aug-Sep;93(8-9):338-46
European journal of cell biology 2014 Aug-Sep;93(8-9):338-46
Defective autophagy and mTORC1 signaling in myotubularin null mice.
Fetalvero KM, Yu Y, Goetschkes M, Liang G, Valdez RA, Gould T, Triantafellow E, Bergling S, Loureiro J, Eash J, Lin V, Porter JA, Finan PM, Walsh K, Yang Y, Mao X, Murphy LO
Molecular and cellular biology 2013 Jan;33(1):98-110
Molecular and cellular biology 2013 Jan;33(1):98-110
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GABARAP antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human GABARAP. This antibody recognizes human, mouse, rat antigen. The GABARAP antibody has been validated for the following applications: ELISA, WB analysis.
