Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12542-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12542-1-AP, RRID:AB_2057753
- Product name
- Annexin VI antibody
- Antibody type
- Polyclonal
- Description
- Annexin VI antibody (Cat. #12542-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Relationship between localization of annexins and dentinogenesis during rat tooth development.
Enterohemorrhagic Escherichia coli targets Annexin A6 and ATG16L1 to inhibit autophagy and induce inflammation.
Small Extracellular Vesicles Orchestrate Cisplatin-Induced Ototoxicity: Potential Biomarker and Targets Discovery.
Annexin A6 mitigates neurological deficit in ischemia/reperfusion injury by promoting synaptic plasticity.
Matrix vesicles from osteoblasts promote atherosclerotic calcification.
Isolation and Comprehensive Analysis of Cochlear Tissue-Derived Small Extracellular Vesicles.
Transcription factor PRRX1-activated ANXA6 facilitates EGFR-PKCα complex formation and enhances cisplatin sensitivity in bladder cancer.
Dynamic Mitochondrial Proteome Under Polyamines Treatment in Cardiac Aging.
Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method.
Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells.
TMT-based proteomics analysis of the cerebral cortex of TauT knockout rats.
Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer.
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
A dynamic plasma membrane proteome analysis of alcohol-induced liver cirrhosis.
Shibui T, Hosoya A, Takahashi M, Takebe H, Shibata S, Irie K
Anatomical record (Hoboken, N.J. : 2007) 2026 Jun;309(6):1667-1679
Anatomical record (Hoboken, N.J. : 2007) 2026 Jun;309(6):1667-1679
Enterohemorrhagic Escherichia coli targets Annexin A6 and ATG16L1 to inhibit autophagy and induce inflammation.
Xu L, Gao M, Wang Y, Zhang B, Zhao W, Lu W, Cao G, Wan C, Hua Y
AIMS microbiology 2025;11(4):984-1006
AIMS microbiology 2025;11(4):984-1006
Small Extracellular Vesicles Orchestrate Cisplatin-Induced Ototoxicity: Potential Biomarker and Targets Discovery.
Ai J, Zhang S, Dai M, Jiang P, Huang J, Xiao H, Lin Y, Tang X, Tong W, He J, Mao Q, Wang Y, Ye Z, Wang T, Chai R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e02627
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e02627
Annexin A6 mitigates neurological deficit in ischemia/reperfusion injury by promoting synaptic plasticity.
Wang Y, Yang Z, Wang R, Zheng Y, Han Z, Fan J, Yan F, Liu P, Luo Y
CNS neuroscience & therapeutics 2024 Feb;30(2):e14639
CNS neuroscience & therapeutics 2024 Feb;30(2):e14639
Matrix vesicles from osteoblasts promote atherosclerotic calcification.
Wang X, Ren J, Fang F, Wang E, Li J, He W, Zhang Z, Shen Y, Liu X
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:79-92
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:79-92
Isolation and Comprehensive Analysis of Cochlear Tissue-Derived Small Extracellular Vesicles.
Jiang P, Ma X, Wang X, Huang J, Wang Y, Ai J, Xiao H, Dai M, Lin Y, Shao B, Tang X, Tong W, Ye Z, Chai R, Zhang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408964
Transcription factor PRRX1-activated ANXA6 facilitates EGFR-PKCα complex formation and enhances cisplatin sensitivity in bladder cancer.
Cao J, Chen S, Wang J, Fan X, Liu S, Li X, Yang L
Life sciences 2024 Dec 15;359:123228
Life sciences 2024 Dec 15;359:123228
Dynamic Mitochondrial Proteome Under Polyamines Treatment in Cardiac Aging.
Zhang H, Yan M, Liu T, Wei P, Chai N, Li L, Wang J, Yu X, Lin Y, Qiu B, Zhao Y
Frontiers in cell and developmental biology 2022;10:840389
Frontiers in cell and developmental biology 2022;10:840389
Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method.
Seo N, Nakamura J, Kaneda T, Tateno H, Shimoda A, Ichiki T, Furukawa K, Hirabayashi J, Akiyoshi K, Shiku H
Journal of extracellular vesicles 2022 Mar;11(3):e12205
Journal of extracellular vesicles 2022 Mar;11(3):e12205
Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells.
Pei T, Su G, Yang J, Gao W, Yang X, Zhang Y, Ren J, Shen Y, Liu X
International journal of molecular sciences 2022 Dec 11;23(24)
International journal of molecular sciences 2022 Dec 11;23(24)
TMT-based proteomics analysis of the cerebral cortex of TauT knockout rats.
Xia Y, Huang X, Mo L, Wang C, Fan W, Huang H
Proteome science 2022 Apr 25;20(1):6
Proteome science 2022 Apr 25;20(1):6
Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer.
Li T, Tao Z, Zhu Y, Liu X, Wang L, Du Y, Cao J, Wang B, Zhang J, Hu X
Cell death & disease 2021 Jul 8;12(7):684
Cell death & disease 2021 Jul 8;12(7):684
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, Wang Z, Fang L, Du R
Journal of proteome research 2019 May 3;18(5):2032-2044
Journal of proteome research 2019 May 3;18(5):2032-2044
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
Sun X, Huang S, Wang X, Zhang X, Wang X
Oncotarget 2018 Jun 8;9(44):27574-27584
Oncotarget 2018 Jun 8;9(44):27574-27584
UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis.
Wang B, Shen J, Wang J
OncoTargets and therapy 2017;10:5303-5309
OncoTargets and therapy 2017;10:5303-5309
A dynamic plasma membrane proteome analysis of alcohol-induced liver cirrhosis.
Jia X, Yin L, Feng Y, Peng X, Ma F, Yao Y, Liu X, Zhang Z, Yuan Z, Zhang L
Proteome science 2012 Jun 8;10(1):39
Proteome science 2012 Jun 8;10(1):39
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12542-1-AP(ANXA6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Annexin VI antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Annexin VI. This antibody recognizes human,mouse,rat antigen. The Annexin VI antibody has been validated for the following applications: ELISA, WB, IHC analysis.