Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- ABIN394570 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6) (AA 831-931) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 831-931
- Isotype
- IgG
- Antibody clone number
- 1E6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Analysis of MMP2 promoter polymorphisms in patients with pseudoxanthoma elasticum.
Pseudoxanthoma elasticum: molecular genetics and putative pathomechanisms.
The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.
Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region.
The R1141X loss-of-function mutation of the ABCC6 gene is a strong genetic risk factor for coronary artery disease.
Zarbock R, Hendig D, Szliska C, Kleesiek K, Götting C
Clinica chimica acta; international journal of clinical chemistry 2010 Oct 9;411(19-20):1487-90
Clinica chimica acta; international journal of clinical chemistry 2010 Oct 9;411(19-20):1487-90
Pseudoxanthoma elasticum: molecular genetics and putative pathomechanisms.
Uitto J, Li Q, Jiang Q
The Journal of investigative dermatology 2010 Mar;130(3):661-70
The Journal of investigative dermatology 2010 Mar;130(3):661-70
The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.
de Boussac H, Ratajewski M, Sachrajda I, Köblös G, Tordai A, Pulaski L, Buday L, Váradi A, Arányi T
The Journal of biological chemistry 2010 Jul 23;285(30):22800-8
The Journal of biological chemistry 2010 Jul 23;285(30):22800-8
Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region.
Costrop LM, Vanakker OO, Van Laer L, Le Saux O, Martin L, Chassaing N, Guerra D, Pasquali-Ronchetti I, Coucke PJ, De Paepe A
Journal of human genetics 2010 Feb;55(2):112-7
Journal of human genetics 2010 Feb;55(2):112-7
The R1141X loss-of-function mutation of the ABCC6 gene is a strong genetic risk factor for coronary artery disease.
Köblös G, Andrikovics H, Prohászka Z, Tordai A, Váradi A, Arányi T
Genetic testing and molecular biomarkers 2010 Feb;14(1):75-8
Genetic testing and molecular biomarkers 2010 Feb;14(1):75-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA