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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Western blot [1]
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- Product number
- GTX70178 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70178, RRID:AB_370371
- Product name
- Estrogen Receptor beta antibody [6A12]
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
Submitted references Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2.
Estrogen receptor beta binds to and regulates three distinct classes of target genes.
Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane.
Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells.
Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells.
Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract.
Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression.
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.
Paruthiyil S, Cvoro A, Tagliaferri M, Cohen I, Shtivelman E, Leitman DC
Breast cancer research and treatment 2011 Oct;129(3):777-84
Breast cancer research and treatment 2011 Oct;129(3):777-84
Estrogen receptor beta binds to and regulates three distinct classes of target genes.
Vivar OI, Zhao X, Saunier EF, Griffin C, Mayba OS, Tagliaferri M, Cohen I, Speed TP, Leitman DC
The Journal of biological chemistry 2010 Jul 16;285(29):22059-66
The Journal of biological chemistry 2010 Jul 16;285(29):22059-66
Selective activation of estrogen receptor-beta target genes by 3,3'-diindolylmethane.
Vivar OI, Saunier EF, Leitman DC, Firestone GL, Bjeldanes LF
Endocrinology 2010 Apr;151(4):1662-7
Endocrinology 2010 Apr;151(4):1662-7
Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells.
Ivanova MM, Mazhawidza W, Dougherty SM, Minna JD, Klinge CM
Molecular and cellular endocrinology 2009 Jun 16;305(1-2):12-21
Molecular and cellular endocrinology 2009 Jun 16;305(1-2):12-21
Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells.
Klinge CM, Wickramasinghe NS, Ivanova MM, Dougherty SM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Jul;22(7):2185-97
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Jul;22(7):2185-97
Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract.
Cvoro A, Paruthiyil S, Jones JO, Tzagarakis-Foster C, Clegg NJ, Tatomer D, Medina RT, Tagliaferri M, Schaufele F, Scanlan TS, Diamond MI, Cohen I, Leitman DC
Endocrinology 2007 Feb;148(2):538-47
Endocrinology 2007 Feb;148(2):538-47
Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression.
Cvoro A, Tzagarakis-Foster C, Tatomer D, Paruthiyil S, Fox MS, Leitman DC
Molecular cell 2006 Feb 17;21(4):555-64
Molecular cell 2006 Feb 17;21(4):555-64
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta.
Tee MK, Rogatsky I, Tzagarakis-Foster C, Cvoro A, An J, Christy RJ, Yamamoto KR, Leitman DC
Molecular biology of the cell 2004 Mar;15(3):1262-72
Molecular biology of the cell 2004 Mar;15(3):1262-72
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- Experimental details
- Non-transfected (¡V) and transfected (+) 293T whole cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor beta antibody [6A12] (GTX70178) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.
