Antibody data

Product number
Ab102374 - Provider product page
Provider
Aladdin Scientific
Product name
Estrogen Receptor beta Antibody
Antibody type
Polyclonal
Description
Rabbit anti Human Estrogen Receptor beta Antibody, Polyclonal, could be used for WB, IHC and so on.ApplicationWB: 1/500-1/1000IHC: 1/50-1/100Protein FunctionNuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 480-530
Vial size
100μl,10μl,1ml,50μl
Concentration
0,6 mg/ml
Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
ESR2 protein structure - Ab102374 shown in red.