RA0791

antibody from Oursmab

Targeting: TNFSF14 CD258, HVEM-L, LIGHT, LTg

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0791

Provider

Oursmab

Product name

Quisovalimab (Biosimilar Reference Antibody) (TNFSF14)

Antibody type

Monoclonal

Description

Quisovalimab is a humanized IgG4 kappa monoclonal antibody that specifically targets LIGHT (TNFSF14), a TNF superfamily cytokine. By binding to and neutralizing LIGHT, it blocks its interaction with the receptors HVEM and LT¦ÂR. This mechanism aims to inhibit LIGHT-mediated pro-inflammatory and co-stimulatory signaling pathways, thereby modulating immune responses. It is being investigated for the treatment of autoimmune diseases and inflammatory conditions, such as ulcerative colitis and rheumatoid arthritis.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.