CABT-B11306

antibody from Creative Diagnostics

Targeting: SAG ARRESTIN, RP47

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B11306

Provider

Creative Diagnostics

Product name

Mouse anti-Pig SAG monoclonal antibody, clone QET-2

Antibody type

Monoclonal

Description

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]

Reactivity

Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

QET-2

Storage

Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.