627202

antibody from BioLegend

Targeting: TRAT1 HSPC062, TCRIM, TRIM

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

627202

Provider

BioLegend

Proper citation

BioLegend Cat#627202, RRID:AB_2240982

Product name

Purified anti-TRIM

Antibody type

Monoclonal

Antigen

Partial recombinant human TRIM (amino acids 29-186)

Description

TRIM is a 30 kD disulfide-linked protein also known as T cell receptor interacting molecule. TRIM is a type III membrane protein containing a very short extracellular domain (8 amino acids). TRIM is highly expressed in T cells with some expression also observed in NK cells. TRIM is a signaling adaptor molecule that links extracellular and intracellular signaling. The TRIM protein is phosphorylated by Src kinases and associates with the PI3K regulatory subunit α after phosphorylation. TRIM has also been shown to associate with TCRα,β, and ?. The TRIM-4 monoclonal antibody recognizes human TRIM and has been shown to be useful for Western blotting, intracellular staining by flow cytometry, and immunofluorescence staining.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

Upon receipt, store undiluted at 4° C.