HPA020081

antibody from Atlas Antibodies

Targeting: MACC1 7A5, SH3BP4L

Western blot (Data presented on provider website)

Antibody Data

Product number

HPA020081

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA020081, RRID:AB_1844386

Product name

Anti-MACC1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human MACC1, Gene description: metastasis associated in colon cancer 1, Alternative Gene Names: 7A5, SH3BP4L, Validated applications: WB, Uniprot ID: Q6ZN28, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.5 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Establishment of Stable Knockdown of MACC1 Oncogene in Patient-Derived Ovarian Cancer Organoids

Hierlmayer S, Hladchenko L, Reichenbach J, Klein C, Mahner S, Trillsch F, Kessler M, Chelariu-Raicu A
Methods and Protocols 2024;7(6):104

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Metastasis Associated in Colorectal Cancer 1 (MACC1) mRNA Expression Is Enhanced in Sporadic Vestibular Schwannoma and Correlates to Deafness

Breun M, Flock K, Feldheim J, Nattmann A, Monoranu C, Herrmann P, Ernestus R, Löhr M, Hagemann C, Stein U
Cancers 2023;15(16):4089

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MACC1 and MET as markers associated with progression and metastasis in cutaneous melanoma

Zhou Y, Rasner C, Giubellino A
Frontiers in Oncology 2023;13

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Core-Clock Genes Regulate Proliferation and Invasion via a Reciprocal Interplay with MACC1 in Colorectal Cancer Cells

Basti A, Malhan D, Dumbani M, Dahlmann M, Stein U, Relógio A
Cancers 2022;14(14):3458

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MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer

Imbastari F, Dahlmann M, Sporbert A, Mattioli C, Mari T, Scholz F, Timm L, Twamley S, Migotti R, Walther W, Dittmar G, Rehm A, Stein U
Cellular and Molecular Life Sciences 2021;78(7):3525-3542

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The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis

Kobelt D, Perez-Hernandez D, Fleuter C, Dahlmann M, Zincke F, Smith J, Migotti R, Popp O, Burock S, Walther W, Dittmar G, Mertins P, Stein U
Oncogene 2021;40(34):5286-5301

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Pro-inflammatory TNF-α and IFN-γ Promote Tumor Growth and Metastasis via Induction of MACC1

Kobelt D, Zhang C, Clayton-Lucey I, Glauben R, Voss C, Siegmund B, Stein U
Frontiers in Immunology 2020;11

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Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway

Qian L, Li X, Ye P, Su H, Wang G, Liu Y, Shen G, Gao Q
Oncology Letters 2017;14(4):4897-4905

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Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis

Hagemann C, Fuchs S, Monoranu C, Herrmann P, Smith J, Hohmann T, Grabiec U, Kessler A, Dehghani F, Lohr M, Ernestus R, Vince G, Stein U
Neuro-Oncology 2013;15(12):1696-1709