130-10081-200

antibody from RayBiotech, Inc.

Targeting: GHRH GHRF

ELISA (Recommended by provider)

Antibody Data

Product number

130-10081-200

Provider

RayBiotech, Inc.

Proper citation

RayBiotech Cat#130-10081-200, RRID:AB_11218000

Product name

Rabbit anti-Human GHRF

Antibody type

Polyclonal

Antigen

Synthetic peptide derived from Human GHRF.

Description

GHRH first appears in the human hypothalamus between 18 and 29 weeks of gestation, which corresponds to the start of production of growth hormone and other somatotropes in fetuses. GHRH is released from neurosecretory nerve terminals of these arcuate neurons, and is carried by the hypothalamo-hypophyseal portal system to the anterior pituitary gland where it stimulates growth hormone (GH) secretion by stimulating the growth hormone-releasing hormone receptor. GHRH is released in a pulsatile manner, stimulating similar pulsatile release of GH. In addition, GHRH also promotes slow-wave sleep directly. Growth hormone is required for normal postnatal growth, bone growth, regulatory effects on protein, carbohydrate, and lipid metabolism. GHRH stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography.

Reactivity

Human

Host

Rabbit

Antigen sequence

This antibody was produced from a r
abbit immunized with the immunogen.
The IgG fraction was purified from
rabbit serum followed by Protein A
/G affinity chromatography.


Isotype

IgG

Vial size

200 µg

Handling

Supplied as lyophilized and purified antibody originally containing PBS, without Preservative Stabilizers, such as Sodium Azide. Final concentration is indicated on the shipping vial. The antibody is stable for at least years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (suggesting with sterile PBS) can also be aliquotted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can also be stored over months at 4°C. Please avoid freeze-thaw cycles.