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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- MA5-17026 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- ABCB5 Monoclonal Antibody (5H3C6)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 5H3C6
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references ABCB5 is activated by MITF and β-catenin and is associated with melanoma differentiation.
B4GALNT1 induces angiogenesis, anchorage independence growth and motility, and promotes tumorigenesis in melanoma by induction of ganglioside GM2/GD2.
A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells.
Louphrasitthiphol P, Chauhan J, Goding CR
Pigment cell & melanoma research 2020 Jan;33(1):112-118
Pigment cell & melanoma research 2020 Jan;33(1):112-118
B4GALNT1 induces angiogenesis, anchorage independence growth and motility, and promotes tumorigenesis in melanoma by induction of ganglioside GM2/GD2.
Yoshida H, Koodie L, Jacobsen K, Hanzawa K, Miyamoto Y, Yamamoto M
Scientific reports 2020 Jan 27;10(1):1199
Scientific reports 2020 Jan 27;10(1):1199
A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells.
Klicks J, Maßlo C, Kluth A, Rudolf R, Hafner M
BMC cancer 2019 Apr 29;19(1):402
BMC cancer 2019 Apr 29;19(1):402
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of ABCB5 using a ABCB5 monoclonal antibody (Product # MA5-17026) against a human ABCB5 recombinant protein.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of ABCB5 using a ABCB5 monoclonal antibody (Product # MA5-17026) against a human ABCB5 recombinant protein.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of ABCB5 using ABCB5 monoclonal antibody (Product # MA5-17026) in A431 (1) cell lysate.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of HepG2 cells using ABCB5 monoclonal antibody (Product # MA5-17026) (Green). Blue: DRAQ5 fluorescent DNA dye. Red: actin filaments have been labeled with phalloidin.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded liver cancer tissues using ABCB5 monoclonal antibody (Product # MA5-17026) followed with DAB staining.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded breast cancer tissues using ABCB5 monoclonal antibody (Product # MA5-17026) followed with DAB staining.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometric analysis of HepG2 cells using ABCB5 monoclonal antibody (Product # MA5-17026) (green) and negative control (purple).
