ABIN2840592

antibody from antibodies-online

Targeting: ABCB5 ABCB5alpha, ABCB5beta, EST422562

Western blot (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN2840592

Provider

antibodies-online

Product name

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5) (AA 1-30), (N-Term) antibody

Antibody type

Polyclonal

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 1-30, N-Term

Antibody clone number

RB16781

Vial size

80 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.

Handling

Avoid freeze-thaw cycles.

References

Submitted references

ABCB5 is a limbal stem cell gene required for corneal development and repair.

Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY
Nature 2014 Jul 17;511(7509):353-7

---

Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance.

Luo Y, Ellis LZ, Dallaglio K, Takeda M, Robinson WA, Robinson SE, Liu W, Lewis KD, McCarter MD, Gonzalez R, Norris DA, Roop DR, Spritz RA, Ahn NG, Fujita M
The Journal of investigative dermatology 2012 Oct;132(10):2440-2450

---

CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry.

Lai CY, Schwartz BE, Hsu MY
Cancer research 2012 Oct 1;72(19):5111-8

---

ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients.

Wilson BJ, Schatton T, Zhan Q, Gasser M, Ma J, Saab KR, Schanche R, Waaga-Gasser AM, Gold JS, Huang Q, Murphy GF, Frank MH, Frank NY
Cancer research 2011 Aug 1;71(15):5307-16

---

Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.

Ramgolam K, Lauriol J, Lalou C, Lauden L, Michel L, de la Grange P, Khatib AM, Aoudjit F, Charron D, Alcaide-Loridan C, Al-Daccak R
PloS one 2011 Apr 15;6(4):e18784

---

ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma.

Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, Sayegh MH, Sadee W, Frank MH
Cancer research 2005 May 15;65(10):4320-33

---

Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter.

Frank NY, Pendse SS, Lapchak PH, Margaryan A, Shlain D, Doeing C, Sayegh MH, Frank MH
The Journal of biological chemistry 2003 Nov 21;278(47):47156-65

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Flow cytometry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS