Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14480-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14480-1-AP, RRID:AB_2199587
- Product name
- TFE3 antibody
- Antibody type
- Polyclonal
- Description
- TFE3 antibody (Cat. #14480-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TFE3-SLC36A1 axis promotes resistance to glucose starvation in kidney cancer cells.
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress.
ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.
Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress.
Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.
The KEAP1-NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis.
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm.
The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma.
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Anti-cancer effect of marchantin C via inducing lung cancer cellular senescence associated with less secretory phenotype.
Terpenoids isolated from Chinese liverworts Lepidozia reptans and their anti-inflammatory activity.
Lv S, Zhang Z, Li Z, Ke Q, Ma X, Li N, Zhao X, Zou Q, Sun L, Song T
The Journal of biological chemistry 2024 May;300(5):107270
The Journal of biological chemistry 2024 May;300(5):107270
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress.
Wang YY, Ni JC, Zhao YQ, Yang X, Niu ZP, Yang XZ, Dong XX, Zhao YH, Hao XJ, Ding X
Journal of Asian natural products research 2024 May;26(5):562-574
Journal of Asian natural products research 2024 May;26(5):562-574
ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.
Koh M, Lim H, Jin H, Kim M, Hong Y, Hwang YK, Woo Y, Kim ES, Kim SY, Kim KM, Lim HK, Jung J, Kang S, Park B, Lee HB, Han W, Lee MS, Moon A
Autophagy 2024 Mar;20(3):659-674
Autophagy 2024 Mar;20(3):659-674
Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress.
Liu C, Xu Y, Yang G, Tao Y, Chang J, Wang S, Cheung TH, Chen J, Zeng YA
Cell stem cell 2024 Jan 4;31(1):89-105.e6
Cell stem cell 2024 Jan 4;31(1):89-105.e6
Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Bu KB, Kim M, Shin MK, Lee SH, Sung JS
International journal of molecular sciences 2024 Jan 22;25(2)
International journal of molecular sciences 2024 Jan 22;25(2)
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150
Cell death and differentiation 2023 Sep;30(9):2135-2150
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
Chae CW, Yoon JH, Lim JR, Park JY, Cho JH, Jung YH, Choi GE, Lee HJ, Han HJ
Autophagy 2023 Oct;19(10):2752-2768
Autophagy 2023 Oct;19(10):2752-2768
TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.
Song T, Lv S, Ma X, Zhao X, Fan L, Zou Q, Li N, Yan Y, Zhang W, Sun L
The Journal of biological chemistry 2023 May;299(5):104621
The Journal of biological chemistry 2023 May;299(5):104621
The KEAP1-NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis.
Ong AJS, Bladen CE, Tigani TA, Karamalakis AP, Evason KJ, Brown KK, Cox AG
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2217425120
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2217425120
TFE3-mediated impairment of lysosomal biogenesis and defective autophagy contribute to fluoride-induced hepatotoxicity.
Hu Z, Xu W, Zhang J, Tang Y, Xing H, Xu P, Ma Y, Niu Q
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Ecotoxicology and environmental safety 2023 Mar 15;253:114674
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV Jr
Nature communications 2022 Oct 7;13(1):5924
Nature communications 2022 Oct 7;13(1):5924
Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm.
Jia Y, Zhang L, Liu Z, Mao C, Ma Z, Li W, Yu F, Wang Y, Huang Y, Zhang W, Zheng J, Wang X, Xu Q, Zhang J, Feng W, Yun C, Liu C, Sun J, Fu Y, Cui Q, Kong W
Cell discovery 2022 Mar 1;8(1):21
Cell discovery 2022 Mar 1;8(1):21
The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma.
Ferro I, Gavini J, Gallo S, Bracher L, Landolfo M, Candinas D, Stroka DM, Polacek N
Autophagy 2022 Jan;18(1):191-203
Autophagy 2022 Jan;18(1):191-203
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
Wang B, Yin X, Gan W, Pan F, Li S, Xiang Z, Han X, Li D
Autophagy 2021 Sep;17(9):2475-2493
Autophagy 2021 Sep;17(9):2475-2493
Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis.
Wang H, Wang N, Xu D, Ma Q, Chen Y, Xu S, Xia Q, Zhang Y, Prehn JHM, Wang G, Ying Z
Autophagy 2020 Sep;16(9):1683-1696
Autophagy 2020 Sep;16(9):1683-1696
Anti-cancer effect of marchantin C via inducing lung cancer cellular senescence associated with less secretory phenotype.
Zhang XL, Ji XT, Sun B, Qian LL, Hu XL, Lou HX, Yuan HQ
Biochimica et biophysica acta. General subjects 2019 Oct;1863(10):1443-1457
Biochimica et biophysica acta. General subjects 2019 Oct;1863(10):1443-1457
Terpenoids isolated from Chinese liverworts Lepidozia reptans and their anti-inflammatory activity.
Li S, Niu H, Qiao Y, Zhu R, Sun Y, Ren Z, Yuan H, Gao Y, Li Y, Chen W, Zhou J, Lou H
Bioorganic & medicinal chemistry 2018 May 15;26(9):2392-2400
Bioorganic & medicinal chemistry 2018 May 15;26(9):2392-2400
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TFE3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TFE3. This antibody recognizes human, mouse, rat antigen. The TFE3 antibody has been validated for the following applications: ELISA, WB analysis.