Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 18705-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18705-1-AP, RRID:AB_10597089
- Product name
- F4/80 antibody
- Antibody type
- Polyclonal
- Description
- F4/80 antibody (Cat. #18705-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The synergistic effect and mechanisms of flavonoids and polysaccharides from Houttuynia cordata on H1N1-induced pneumonia in mice.
Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition.
G-CSF partially mediates bone loss induced by Staphylococcus aureus infection in mice.
α7-nAChR Activation Has an Opposite Effect on Healing of Covered and Uncovered Wounds.
Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing.
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.
Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice.
Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues.
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes.
Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism.
p16 deficiency promotes nonalcoholic steatohepatitis via regulation of hepatic oxidative stress.
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation.
Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy.
Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma.
Amelioration of nonalcoholic fatty liver disease by hepatic stimulator substance via preservation of carnitine palmitoyl transferase-1 activity.
Resveratrol attenuates inflammation and oxidative stress in epididymal white adipose tissue: implications for its involvement in improving steroidogenesis in diet-induced obese mice.
The liver is populated by a broad spectrum of markers for macrophages. In alcoholic hepatitis the macrophages are M1 and M2.
Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury.
Ling L, Ren A, Lu Y, Zhang Y, Zhu H, Tu P, Li H, Chen D
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115761
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115761
Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition.
Xiong C, Zhu Y, Xue M, Jiang Y, Zhong Y, Jiang L, Shi M, Chen H
Aging 2021 Jan 10;13(3):3386-3404
Aging 2021 Jan 10;13(3):3386-3404
G-CSF partially mediates bone loss induced by Staphylococcus aureus infection in mice.
Hou Y, Qin H, Jiang N, Liu G, Wu H, Bai L, Yu B, Zhang X
Clinical science (London, England : 1979) 2019 Jun 28;133(12):1297-1308
Clinical science (London, England : 1979) 2019 Jun 28;133(12):1297-1308
α7-nAChR Activation Has an Opposite Effect on Healing of Covered and Uncovered Wounds.
Li JY, Jiang SK, Wang LL, Zhang MZ, Wang S, Jiang ZF, Liu YL, Cheng H, Zhang M, Zhao R, Guan DW
Inflammation 2018 Mar;41(2):474-484
Inflammation 2018 Mar;41(2):474-484
Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing.
Huang D, Wei W, Xie F, Zhu X, Zheng L, Lv Z
Andrologia 2018 Feb;50(1)
Andrologia 2018 Feb;50(1)
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.
Yu Z, Zhao S, Ren L, Wang L, Chen Z, Hoffman RM, Zhou J
Oncotarget 2017 Sep 8;8(38):63461-63483
Oncotarget 2017 Sep 8;8(38):63461-63483
Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice.
Shon SM, Jang HJ, Schellingerhout D, Kim JY, Ryu WS, Lee SK, Kim J, Park JY, Oh JH, Kang JW, Je KH, Park JE, Kim K, Kwon IC, Lee J, Nahrendorf M, Park JH, Kim DE
Circulation journal : official journal of the Japanese Circulation Society 2017 Sep 25;81(10):1528-1536
Circulation journal : official journal of the Japanese Circulation Society 2017 Sep 25;81(10):1528-1536
Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues.
Zhao YY, Yang R, Xiao M, Guan MJ, Zhao N, Zeng T
Toxicology 2017 Sep 1;390:53-60
Toxicology 2017 Sep 1;390:53-60
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Qiu Y, Sui X, Cao S, Li X, Ning Y, Wang S, Yin L, Zhi X
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes.
Lu C, Xu W, Shao J, Zhang F, Chen A, Zheng S
Toxicological sciences : an official journal of the Society of Toxicology 2017 Feb;155(2):432-443
Toxicological sciences : an official journal of the Society of Toxicology 2017 Feb;155(2):432-443
Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism.
Liao W, Liu H, Zhang Y, Jung JH, Chen J, Su X, Kim YC, Flores ER, Wang SM, Czarny-Ratajczak M, Li W, Zeng SX, Lu H
Scientific reports 2017 Aug 21;7(1):9020
Scientific reports 2017 Aug 21;7(1):9020
p16 deficiency promotes nonalcoholic steatohepatitis via regulation of hepatic oxidative stress.
Lv F, Wu J, Miao D, An W, Wang Y
Biochemical and biophysical research communications 2017 Apr 29;486(2):264-269
Biochemical and biophysical research communications 2017 Apr 29;486(2):264-269
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Ding C, Zhao Y, Shi X, Zhang N, Zu G, Li Z, Zhou J, Gao D, Lv L, Tian X, Yao J
Scientific reports 2016 Jun 27;6:28734
Scientific reports 2016 Jun 27;6:28734
Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation.
Lu C, Xu W, Zhang F, Shao J, Zheng S
Toxicology 2016 Jul 15;365:35-47
Toxicology 2016 Jul 15;365:35-47
Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy.
Jang HS, Padanilam BJ
American journal of physiology. Renal physiology 2015 Sep 15;309(6):F540-50
American journal of physiology. Renal physiology 2015 Sep 15;309(6):F540-50
Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma.
Zhang LF, Lou JT, Lu MH, Gao C, Zhao S, Li B, Liang S, Li Y, Li D, Liu MF
The EMBO journal 2015 Nov 3;34(21):2671-85
The EMBO journal 2015 Nov 3;34(21):2671-85
Amelioration of nonalcoholic fatty liver disease by hepatic stimulator substance via preservation of carnitine palmitoyl transferase-1 activity.
Xiao W, Ren M, Zhang C, Li S, An W
American journal of physiology. Cell physiology 2015 Aug 15;309(4):C215-27
American journal of physiology. Cell physiology 2015 Aug 15;309(4):C215-27
Resveratrol attenuates inflammation and oxidative stress in epididymal white adipose tissue: implications for its involvement in improving steroidogenesis in diet-induced obese mice.
Lv ZM, Wang Q, Chen YH, Wang SH, Huang DQ
Molecular reproduction and development 2015 Apr;82(4):321-8
Molecular reproduction and development 2015 Apr;82(4):321-8
The liver is populated by a broad spectrum of markers for macrophages. In alcoholic hepatitis the macrophages are M1 and M2.
Lee J, French B, Morgan T, French SW
Experimental and molecular pathology 2014 Feb;96(1):118-25
Experimental and molecular pathology 2014 Feb;96(1):118-25
Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury.
Ying Y, Kim J, Westphal SN, Long KE, Padanilam BJ
Journal of the American Society of Nephrology : JASN 2014 Dec;25(12):2707-16
Journal of the American Society of Nephrology : JASN 2014 Dec;25(12):2707-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 18705-1-AP(F4-80 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 18705-1-AP(F4-80 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The F4/80 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of mouse F4/80. This antibody recognizes human antigen. The F4/80 antibody has been validated for the following applications: ELISA, WB, IHC analysis.