Antibody data
- Antibody Data
- Antigen structure
- References [28]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10944-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10944-1-AP, RRID:AB_2084279
- Product name
- CRH/CRF antibody
- Antibody type
- Polyclonal
- Description
- CRH/CRF antibody (Cat. #10944-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system.
Electroacupuncture pretreatment mediates sympathetic nerves to alleviate myocardial ischemia-reperfusion injury via CRH neurons in the paraventricular nucleus of the hypothalamus.
Central 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology.
Limosilactobacillus reuteri administration alters the gut-brain-behavior axis in a sex-dependent manner in socially monogamous prairie voles.
Reproductive effects of pubertal exposure to neonicotinoid thiacloprid in immature male mice.
Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Cocaine Regulates NLRP3 Inflammasome Activity and CRF Signaling in a Region- and Sex-Dependent Manner in Rat Brain.
Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR.
Local CRF and oxytocin receptors correlate with female experience-driven avoidance change and hippocampal neuronal plasticity.
Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition.
A procedure in mice to obtain intact pituitary-infundibulum-hypothalamus preparations: a method to evaluate the reconstruction of hypothalamohypophyseal system.
Heat Stress during Summer Attenuates Expression of the Hypothalamic Kisspeptin, an Upstream Regulator of the Hypothalamic-Pituitary-Gonadal Axis, in Domestic Sows.
Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia.
Postpartum maternal exposure to predator odor alters offspring antipredator behavior, basal HPA axis activity and immunoglobulin levels in adult Brandt's voles.
Effects of maternal deprivation and environmental enrichment on anxiety-like and depression-like behaviors correlate with oxytocin system and CRH level in the medial-lateral habenula.
Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system.
Stress and Nasal Allergy: Corticotropin-Releasing Hormone Stimulates Mast Cell Degranulation and Proliferation in Human Nasal Mucosa.
Single-cell transcriptome analysis identifies a unique tumor cell type producing multiple hormones in ectopic ACTH and CRH secreting pheochromocytoma.
Social isolation alters behavior, the gut-immune-brain axis, and neurochemical circuits in male and female prairie voles.
Colocalization of dopamine receptors in BDNF-expressing peptidergic neurons in the paraventricular nucleus of rats.
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
A combination of depression and liver Qi stagnation and spleen deficiency syndrome using a rat model.
PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.
Paternal deprivation affects social behaviors and neurochemical systems in the offspring of socially monogamous prairie voles.
Effects of chronic noise on mRNA and protein expression of CRF family molecules and its relationship with p-tau in the rat prefrontal cortex.
Expression of stress hormones AVP and CRH in the hypothalamus of Mus musculus following water and food deprivation.
Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test.
Li K, Feng Z, Xiong Z, Pan J, Zhou M, Li W, Ou Y, Wu G, Che M, Gong H, Peng J, Wang X, Qi S, Peng J
Neural regeneration research 2024 Oct 1;19(10):2249-2258
Neural regeneration research 2024 Oct 1;19(10):2249-2258
Electroacupuncture pretreatment mediates sympathetic nerves to alleviate myocardial ischemia-reperfusion injury via CRH neurons in the paraventricular nucleus of the hypothalamus.
Zhou J, Zhang B, Zhou X, Zhang F, Shu Q, Wu Y, Chang HM, Hu L, Cai RL, Yu Q
Chinese medicine 2024 Mar 6;19(1):43
Chinese medicine 2024 Mar 6;19(1):43
Central 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology.
Lee JS, Kang JY, Park SY, Hwang SJ, Bae SJ, Son CG
Journal of translational medicine 2024 Jan 8;22(1):34
Journal of translational medicine 2024 Jan 8;22(1):34
Limosilactobacillus reuteri administration alters the gut-brain-behavior axis in a sex-dependent manner in socially monogamous prairie voles.
Donovan M, Mackey CS, Lynch MDJ, Platt GN, Brown AN, Washburn BK, Trickey DJ, Curtis JT, Liu Y, Charles TC, Wang Z, Jones KM
Frontiers in microbiology 2023;14:1015666
Frontiers in microbiology 2023;14:1015666
Reproductive effects of pubertal exposure to neonicotinoid thiacloprid in immature male mice.
Zou Y, Zhang L, Yue M, Zou Z, Wu X, Zhang Q, Huang Y, Zeng S, Chen C, Gao J
Toxicology and applied pharmacology 2023 Sep 1;474:116629
Toxicology and applied pharmacology 2023 Sep 1;474:116629
Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1.
Jiang C, Wang C, Qu W, Wang Y, Wang H, Wei X, Wang M, He Q, Wang Y, Yuan L, Gao Y
Heliyon 2023 Nov;9(11):e21743
Heliyon 2023 Nov;9(11):e21743
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Cocaine Regulates NLRP3 Inflammasome Activity and CRF Signaling in a Region- and Sex-Dependent Manner in Rat Brain.
Cheng Y, Dempsey RE, Roodsari SK, Shuboni-Mulligan DD, George O, Sanford LD, Guo ML
Biomedicines 2023 Jun 23;11(7)
Biomedicines 2023 Jun 23;11(7)
Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR.
Wei F, Deng X, Ma B, Li W, Chen Y, Zhao L, Zhang Y, Zheng T, Xian D, He Y, Zhang L, Jing Y
Cellular and molecular neurobiology 2023 Jul;43(5):2129-2147
Cellular and molecular neurobiology 2023 Jul;43(5):2129-2147
Local CRF and oxytocin receptors correlate with female experience-driven avoidance change and hippocampal neuronal plasticity.
Wei F, Li W, Ma B, Yan Z, Wang Z, Zhang L, Xian D, He Y, Deng X, Chen Y, Tingjuan Z, Zhang J, Jing Y
Neurochemistry international 2023 Feb;163:105485
Neurochemistry international 2023 Feb;163:105485
Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition.
Wang X, Sun Z, Yang T, Lin F, Ye S, Yan J, Li T, Chen J
mSystems 2023 Aug 31;8(4):e0041523
mSystems 2023 Aug 31;8(4):e0041523
A procedure in mice to obtain intact pituitary-infundibulum-hypothalamus preparations: a method to evaluate the reconstruction of hypothalamohypophyseal system.
Li K, Xiong Z, Zhou M, Ou Y, Li W, Wu G, Che M, Gong H, Wang X, Peng J, Zheng X, Li J, Feng Z, Peng J
Pituitary 2023 Apr;26(2):197-208
Pituitary 2023 Apr;26(2):197-208
Heat Stress during Summer Attenuates Expression of the Hypothalamic Kisspeptin, an Upstream Regulator of the Hypothalamic-Pituitary-Gonadal Axis, in Domestic Sows.
Kim HD, Kim YJ, Jang M, Bae SG, Yun SH, Lee MR, Seo YR, Cho JK, Kim SJ, Lee WJ
Animals : an open access journal from MDPI 2022 Oct 28;12(21)
Animals : an open access journal from MDPI 2022 Oct 28;12(21)
Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia.
Bruce JK, Burns GL, Sinn Soh W, Nair PM, Sherwin S, Fan K, Dowling LR, Goggins BJ, Koloski N, Potter M, Bollipo S, Foster R, Gan LT, Veysey M, Philpott DJ, Girardin SE, Holtmann G, Kaiko GE, Walker MM, Talley NJ, Keely S
Brain, behavior, and immunity 2022 Mar;101:335-345
Brain, behavior, and immunity 2022 Mar;101:335-345
Postpartum maternal exposure to predator odor alters offspring antipredator behavior, basal HPA axis activity and immunoglobulin levels in adult Brandt's voles.
Wu R, Li S, Huang Y, Pang J, Cai Y, Zhang X, Jiang T, Yang S, Wei W
Behavioural brain research 2022 Jan 7;416:113532
Behavioural brain research 2022 Jan 7;416:113532
Effects of maternal deprivation and environmental enrichment on anxiety-like and depression-like behaviors correlate with oxytocin system and CRH level in the medial-lateral habenula.
Wei F, Xian D, He Y, Yan Z, Deng X, Chen Y, Zhao L, Zhang Y, Li W, Ma B, Zhang J, Jing Y
Peptides 2022 Dec;158:170882
Peptides 2022 Dec;158:170882
Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system.
Su H, Liu N, Zhang Y, Kong J
Journal of advanced research 2021 Nov;33:69-80
Journal of advanced research 2021 Nov;33:69-80
Stress and Nasal Allergy: Corticotropin-Releasing Hormone Stimulates Mast Cell Degranulation and Proliferation in Human Nasal Mucosa.
Yamanaka-Takaichi M, Mizukami Y, Sugawara K, Sunami K, Teranishi Y, Kira Y, Paus R, Tsuruta D
International journal of molecular sciences 2021 Mar 9;22(5)
International journal of molecular sciences 2021 Mar 9;22(5)
Single-cell transcriptome analysis identifies a unique tumor cell type producing multiple hormones in ectopic ACTH and CRH secreting pheochromocytoma.
Zhang X, Lian P, Su M, Ji Z, Deng J, Zheng G, Wang W, Ren X, Jiang T, Zhang P, Li H
eLife 2021 Dec 14;10
eLife 2021 Dec 14;10
Social isolation alters behavior, the gut-immune-brain axis, and neurochemical circuits in male and female prairie voles.
Donovan M, Mackey CS, Platt GN, Rounds J, Brown AN, Trickey DJ, Liu Y, Jones KM, Wang Z
Neurobiology of stress 2020 Nov;13:100278
Neurobiology of stress 2020 Nov;13:100278
Colocalization of dopamine receptors in BDNF-expressing peptidergic neurons in the paraventricular nucleus of rats.
Zhou L, Zhang Y, Lian H, Li Y, Wang Z
Journal of chemical neuroanatomy 2020 Jul;106:101794
Journal of chemical neuroanatomy 2020 Jul;106:101794
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Zhu C, Zhao L, Zhao J, Zhang S
International journal of molecular medicine 2020 Jan;45(1):53-60
International journal of molecular medicine 2020 Jan;45(1):53-60
A combination of depression and liver Qi stagnation and spleen deficiency syndrome using a rat model.
Li XJ, Qiu WQ, Da XL, Hou YJ, Ma QY, Wang TY, Zhou XM, Song M, Bian QL, Chen JX
Anatomical record (Hoboken, N.J. : 2007) 2020 Aug;303(8):2154-2167
Anatomical record (Hoboken, N.J. : 2007) 2020 Aug;303(8):2154-2167
PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.
Oleari R, Caramello A, Campinoti S, Lettieri A, Ioannou E, Paganoni A, Fantin A, Cariboni A, Ruhrberg C
Development (Cambridge, England) 2019 Nov 5;146(21)
Development (Cambridge, England) 2019 Nov 5;146(21)
Paternal deprivation affects social behaviors and neurochemical systems in the offspring of socially monogamous prairie voles.
Tabbaa M, Lei K, Liu Y, Wang Z
Neuroscience 2017 Feb 20;343:284-297
Neuroscience 2017 Feb 20;343:284-297
Effects of chronic noise on mRNA and protein expression of CRF family molecules and its relationship with p-tau in the rat prefrontal cortex.
Gai Z, Li K, Sun H, She X, Cui B, Wang R
Journal of the neurological sciences 2016 Sep 15;368:307-13
Journal of the neurological sciences 2016 Sep 15;368:307-13
Expression of stress hormones AVP and CRH in the hypothalamus of Mus musculus following water and food deprivation.
Yadawa AK, Chaturvedi CM
General and comparative endocrinology 2016 Dec 1;239:13-20
General and comparative endocrinology 2016 Dec 1;239:13-20
Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test.
Chen F, Chen S, Liu S, Zhang C, Peng G
Neuropharmacology 2015 Aug;95:226-33
Neuropharmacology 2015 Aug;95:226-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 10944-1-AP(CRH antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CRH/CRF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CRH/CRF. This antibody recognizes human,mouse,rat antigen. The CRH/CRF antibody has been validated for the following applications: ELISA, WB, IHC analysis.