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Learn16145-1-AP
antibody from Proteintech Group
Targeting: POLR1E
FLJ13390, FLJ13970, PAF53, PRAF1, RPA49
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- 16145-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16145-1-AP, RRID:AB_2167341
- Product name
- POLR1E antibody
- Antibody type
- Polyclonal
- Description
- POLR1E antibody (Cat. #16145-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Expression of RNA polymerase I catalytic core is influenced by RPA12.
PAF49: An RNA Polymerase I subunit essential for rDNA transcription and stabilization of PAF53.
Nucleoli and the nucleoli-centromere association are dynamic during normal development and in cancer.
Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress.
lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription.
Quinacrine Depletes BCR-ABL and Suppresses Ph-Positive Leukemia Cells.
Conditional depletion of the RNA polymerase I subunit PAF53 reveals that it is essential for mitosis and enables identification of functional domains.
Ford BL, Wei T, Liu H, Scull CE, Najmi SM, Pitts S, Fan W, Schneider DA, Laiho M
PloS one 2023;18(5):e0285660
PloS one 2023;18(5):e0285660
PAF49: An RNA Polymerase I subunit essential for rDNA transcription and stabilization of PAF53.
McNamar R, Freeman E, Baylor KN, Fakhouri AM, Huang S, Knutson BA, Rothblum LI
The Journal of biological chemistry 2023 Aug;299(8):104951
The Journal of biological chemistry 2023 Aug;299(8):104951
Nucleoli and the nucleoli-centromere association are dynamic during normal development and in cancer.
Rodrigues A, MacQuarrie KL, Freeman E, Lin A, Willis AB, Xu Z, Alvarez AA, Ma Y, White BEP, Foltz DR, Huang S
Molecular biology of the cell 2023 Apr 1;34(4):br5
Molecular biology of the cell 2023 Apr 1;34(4):br5
Identification of an E3 ligase that targets the catalytic subunit of RNA Polymerase I upon transcription stress.
Pitts S, Liu H, Ibrahim A, Garg A, Felgueira CM, Begum A, Fan W, Teh S, Low JY, Ford B, Schneider DA, Hay R, Laiho M
The Journal of biological chemistry 2022 Dec;298(12):102690
The Journal of biological chemistry 2022 Dec;298(12):102690
lncRNA SLERT controls phase separation of FC/DFCs to facilitate Pol I transcription.
Wu M, Xu G, Han C, Luan PF, Xing YH, Nan F, Yang LZ, Huang Y, Yang ZH, Shan L, Yang L, Liu J, Chen LL
Science (New York, N.Y.) 2021 Jul 30;373(6554):547-555
Science (New York, N.Y.) 2021 Jul 30;373(6554):547-555
Quinacrine Depletes BCR-ABL and Suppresses Ph-Positive Leukemia Cells.
Lei H, Tu Y, Yang L, Jin J, Luo H, Xu H, Kang J, Zhou L, Wu Y
Cancer investigation 2019;37(6):242-252
Cancer investigation 2019;37(6):242-252
Conditional depletion of the RNA polymerase I subunit PAF53 reveals that it is essential for mitosis and enables identification of functional domains.
McNamar R, Abu-Adas Z, Rothblum K, Knutson BA, Rothblum LI
The Journal of biological chemistry 2019 Dec 27;294(52):19907-19922
The Journal of biological chemistry 2019 Dec 27;294(52):19907-19922
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 16145-1-AP(POLR1E antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The POLR1E antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human POLR1E. This antibody recognizes human,mouse,rat antigen. The POLR1E antibody has been validated for the following applications: ELISA, WB, IP analysis.
