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- References [9]
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- Product number
- 14661-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14661-1-AP, RRID:AB_2163294
- Product name
- PHLDA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PHLDA2 antibody (Cat. #14661-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references M6A modification-related genes characterize prognostic risk and immune regulation in lung adenocarcinoma.
LncRNA USP2-AS1 facilitates colorectal cancer development through the PHLDA2/PI3K/AKT axis.
Sini decoction-polysaccharide compound regulates proliferation, apoptosis, and glycolysis of liver cancer cells through PHLDA2/ANXA2.
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.
Characteristics of lactate metabolism phenotype in hepatocellular carcinoma.
FOSL1 transcriptionally regulates PHLDA2 to promote 5-FU resistance in colon cancer cells.
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Inhibition of PHLDA2 transcription by DNA methylation and YY1 in goat placenta.
Liu X, Li S, Zhou M, Ding N, Chen J, Zhou N
BMC cancer 2026 Jan 16;26(1):226
BMC cancer 2026 Jan 16;26(1):226
LncRNA USP2-AS1 facilitates colorectal cancer development through the PHLDA2/PI3K/AKT axis.
Zhu J, Lin S, Chang L, Luo Q, Qian M, Ding J, Li J, Pu J, Wang K
Experimental cell research 2025 Jul 15;450(2):114649
Experimental cell research 2025 Jul 15;450(2):114649
Sini decoction-polysaccharide compound regulates proliferation, apoptosis, and glycolysis of liver cancer cells through PHLDA2/ANXA2.
Shen C, Huang P, Xie W, Ni X, Gao J
Translational cancer research 2024 Oct 31;13(10):5574-5587
Translational cancer research 2024 Oct 31;13(10):5574-5587
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.
Yang X, Wang Z, Samovich SN, Kapralov AA, Amoscato AA, Tyurin VA, Dar HH, Li Z, Duan S, Kon N, Chen D, Tycko B, Zhang Z, Jiang X, Bayir H, Stockwell BR, Kagan VE, Gu W
Cell metabolism 2024 Apr 2;36(4):762-777.e9
Cell metabolism 2024 Apr 2;36(4):762-777.e9
Characteristics of lactate metabolism phenotype in hepatocellular carcinoma.
Zhang J, Dong K, Zhang X, Li C, Yu J, Wang W
Scientific reports 2023 Nov 11;13(1):19674
Scientific reports 2023 Nov 11;13(1):19674
FOSL1 transcriptionally regulates PHLDA2 to promote 5-FU resistance in colon cancer cells.
Liu G, Wang H, Ran R, Wang Y, Li Y
Pathology, research and practice 2023 Jun;246:154496
Pathology, research and practice 2023 Jun;246:154496
Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M
Nature communications 2022 Jul 13;13(1):4063
Nature communications 2022 Jul 13;13(1):4063
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Ma Z, Lou S, Jiang Z
Aging 2020 May 8;12(9):7985-8000
Aging 2020 May 8;12(9):7985-8000
Inhibition of PHLDA2 transcription by DNA methylation and YY1 in goat placenta.
Wang R, Su L, Yu S, Ma X, Jiang C, Yu Y
Gene 2020 May 20;739:144512
Gene 2020 May 20;739:144512
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHLDA2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PHLDA2. This antibody recognizes human antigen. The PHLDA2 antibody has been validated for the following applications: ELISA, WB analysis.
