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- References [583]
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- Product number
- 21865-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21865-1-AP, RRID:AB_11142677
- Product name
- IL-6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IL-6 antibody (Cat. #21865-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bifunctional TRPV1 Targeted Magnetothermal Switch to Attenuate Osteoarthritis Progression.
Blocking SLC7A11 attenuates the proliferation of esophageal squamous cell carcinoma cells.
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Exploring the Action Mechanism and Validation of the Key Pathways of Dendrobium officinale Throat-clearing Formula for the Treatment of Chronic Pharyngitis Based on Network Pharmacology.
Concomitant NAFLD Facilitates Liver Metastases and PD-1-Refractory by Recruiting MDSCs via CXCL5/CXCR2 in Colorectal Cancer.
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Unveiling the Mechanism of the ChaiShao Shugan Formula Against Triple-Negative Breast Cancer.
MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts.
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Increased expression of in situ CD123 and reduced Toll-like receptor 7/9 signalling pathway suggest impaired activation of plasmacytoid dendritic cells in recurrent erythema multiforme.
Untargeted serum and gastric metabolomics and network pharmacology analysis reveal the superior efficacy of zingiberis rhizoma recens-/euodiae fructus-processed Coptidis Rhizoma on gastric ulcer rats.
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.
Vincamine alleviates brain injury by attenuating neuroinflammation and oxidative damage in a mouse model of Parkinson's disease through the NF-κB and Nrf2/HO-1 signaling pathways.
Artificial nonenzymatic antioxidant Prussian blue/KGM-BSA nanocomposite hydrogel dressing as ROS scavenging for diabetic wound healing.
IL-6 Up-Regulates Expression of LIM-Domain Only Protein 4 in Psoriatic Keratinocytes through Activation of the MEK/ERK/NF-κB Pathway.
Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2.
Rap1GAP exacerbates myocardial infarction by regulating the AMPK/SIRT1/NF-κB signaling pathway.
Morusin Alleviates Aortic Valve Calcification by Inhibiting Valve Interstitial Cell Senescence Through Ccnd1/Trim25/Nrf2 Axis.
Bioengineered Hydrogels Recapitulate Fibroblast Heterogeneity in Cancer.
Prevotella, a dominant bacterium in young people with stage Ⅲ periodontitis, related to the arachidonic acid metabolism pathway.
Chondroprotective effects of Apolipoprotein D in knee osteoarthritis mice through the PI3K/AKT/mTOR signaling pathway.
Transcriptomics-based identification of TYROBP and TLR8 as novel macrophage-related biomarkers for the diagnosis of acute rejection after kidney transplantation.
Corneal Stroma Analysis and Related Ocular Manifestations in Recovered COVID-19 Patients.
Knee Osteotomy Decreases Joint Inflammation Based on Synovial Histology and Synovial Fluid Analysis.
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
M1 Macrophage-Derived Exosome LncRNA PVT1 Promotes Inflammation and Pyroptosis of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm by Inhibiting miR-186-5p and Regulating HMGB1.
Valproate attenuates somatic hyperalgesia induced by orofacial inflammation combined with stress through inhibiting spinal IL-6 and STAT1 phosphorylation.
Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy.
Novel mechanism of Clostridium butyricum alleviated coprophagy prevention-induced intestinal inflammation in rabbit.
S100A9 aggravates early brain injury after subarachnoid hemorrhage via inducing neuroinflammation and inflammasome activation.
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Inhibition of PKM2 suppresses osteoclastogenesis and alleviates bone loss in mouse periodontitis.
Down-regulation of MKP-1 in hippocampus protects against stress-induced depression-like behaviors and neuroinflammation.
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis.
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Forsythiaside A attenuates lipopolysaccharide-induced mouse mastitis by activating autophagy and regulating gut microbiota and metabolism.
Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/STAT3 signaling pathway.
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway.
TERT activation targets DNA methylation and multiple aging hallmarks.
Ciliary neurotrophic factor promotes the development of homocysteine-induced vascular endothelial injury through inflammation mediated by the JAK2/STAT3 signaling pathway.
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
Self-assembled and dynamic bond crosslinked herb-polysaccharide hydrogel with anti-inflammation and pro-angiogenesis effects for burn wound healing.
Betaine eliminates CFA-induced depressive-like behaviour in mice may be through inhibition of microglia and astrocyte activation and polarization.
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.
The clock gene Bmal1 controls inflammatory mediators in rheumatoid arthritis fibroblast-like synoviocytes.
Jianpi Huayu Decoction suppresses cellular senescence in colorectal cancer via p53-p21-Rb pathway: Network pharmacology and in vivo validation.
A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.
The improvement of homocysteine-induced myocardial inflammation by vitamin D depends on activation of NFE2L2 mediated MTHFR.
Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells.
Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy.
Identification of differentially expressed genes associated with ferroptosis in Crohn's disease.
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1.
Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation.
FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion.
Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver.
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
NOD2 contributes to Parvimonas micra-induced bone resorption in diabetic rats with experimental periodontitis.
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
A gelatin methacryloyl (GelMA) treated with gallic acid and coated with specially designed nanoparticles derived from ginseng enhances the healing of wounds in diabetic rats.
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Ligation of cervical lymphatic vessels decelerates blood clearance and worsens outcomes after experimental subarachnoid hemorrhage.
Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis.
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Intestinal edema induced by LPS-induced endotoxemia is associated with an inflammasome adaptor ASC.
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
A novel immunogenic cell death-related subtype classification and risk signature for predicting prognosis and immunotherapy efficacy in gastric cancer.
PTPRC promoted CD8+ T cell mediated tumor immunity and drug sensitivity in breast cancer: based on pan-cancer analysis and artificial intelligence modeling of immunogenic cell death-based drug sensitivity stratification.
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Suppression of tumorigenesis in LUAD by LRP1B through regulation of the IL-6-JAK-STAT3 pathway.
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Sanguisorba officinalis L. promotes diabetic wound healing in rats through inflammation response mediated by macrophage.
Astragaloside IV attenuates high glucose-induced NF-κB-mediated inflammation through activation of PI3K/AKT-ERK-dependent Nrf2/ARE signaling pathway in glomerular mesangial cells.
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model.
Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.
Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer.
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Discovery of the Diphenyl 6-Oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide Analogue J27 for the Treatment of Acute Lung Injury and Sepsis by Targeting JNK2 and Inhibiting the JNK2-NF-κB/MAPK Pathway.
Inducible nitric oxide synthase activity mediates TNF-α-induced endothelial cell dysfunction.
Ki67-targeted oncolytic adenovirus expressing IL-15 improves intratumoral T cell infiltration and PD-L1 expression in glioblastoma.
Fisetin treatment alleviates kidney injury in mice with diabetes-exacerbated atherosclerosis through inhibiting CD36/fibrosis pathway.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Novel pterostilbene derivatives ameliorate heart failure by reducing oxidative stress and inflammation through regulating Nrf2/NF-κB signaling pathway.
Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats.
Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation.
Role of SIRT2 in intestinal barrier under cold exposure.
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Disfunction of communication among immune cells in minimal-deviation adenocarcinoma of the cervix as an immunotherapeutic opportunity.
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer's Disease.
Sleep deprivation alleviates depression-like behaviors in mice via inhibiting immune and inflammatory pathways and improving neuroplasticity.
Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid.
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Polydopamine-Pd nanozymes as potent ROS scavengers in combination with near-infrared irradiation for osteoarthritis treatment.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Effects of gradient high-field static magnetic fields on diabetic mice.
Metformin Attenuates the Inflammatory Response via the Regulation of Synovial M1 Macrophage in Osteoarthritis.
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam.
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Reversing inflammatory microenvironment by a single intra-articular injection of multi-stimulus responsive lipogel to relieve rheumatoid arthritis and promote joint repair.
RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury.
STING/TBK1 Regulates Inflammation in Macrophages and Titanium Particles-Induced Osteolysis.
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Dietary cholesterol drives the development of nonalcoholic steatohepatitis by altering gut microbiota mediated bile acid metabolism in high-fat diet fed mice.
Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease.
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome.
Akkermansia muciniphila protects mice against an emerging tick-borne viral pathogen.
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice.
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
The significance of nanofiber polyglycolic acid for promoting tissue repair in a rat subcutaneous implantation model.
Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis.
Enzymatic one-pot preparation of carboxylmethyl chitosan-based hydrogel with inherent antioxidant and antibacterial properties for accelerating wound healing.
Long-Term High-Fat Diet Consumption Induces Cognitive Decline Accompanied by Tau Hyper-Phosphorylation and Microglial Activation in Aging.
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury.
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic nephropathy.
Interleukin 6 promotes BMP9-induced osteoblastic differentiation through Stat3/mTORC1 in mouse embryonic fibroblasts.
Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.
Resveratrol and its analogs suppress HIV replication, oxidative stress, and inflammation in macrophages.
An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.
The outer membrane protein of Fusobacterium necrophorum, 43K OMP, stimulates inflammatory cytokine production through nuclear factor kappa B activation.
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD(+)-biosynthetic and consuming enzymes.
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
EEF1A2 accelerates the protein translation of chemokine in rat myocardial cells induced by ischemia-reperfusion.
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Up-regulation of PPAR-γ involved in the therapeutic effect of icariin on cigarette smoke-induced inflammation.
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.
Regulatory T cells showed characteristics of T helper-17(Th17) cells in mice periodontitis model.
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways.
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer.
Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
SM22α Deletion Contributes to Neurocognitive Impairment in Mice through Modulating Vascular Smooth Muscle Cell Phenotypes.
IL-7-Treated Periodontal Ligament Cells Regulate Local Immune Homeostasis by Modulating Treg/Th17 Cell Polarization.
Orai1-mediated store-operated Ca(2+) entry promotes cervical cancer progression through IL-6 signaling.
Experimental Periodontitis Deteriorates Cognitive Function and Impairs Insulin Signaling in a Streptozotocin-Induced Alzheimer's Disease Rat Model.
CIDEC: A Potential Factor in Diabetic Vascular Inflammation.
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment.
DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status.
Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain.
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC.
Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration.
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Intra-Articular Injection of Adipose-Derived Stem Cells Ameliorates Pain and Cartilage Anabolism/Catabolism in Osteoarthritis: Preclinical and Clinical Evidences.
A Novel Pyroptosis-Related Gene Signature for Predicting Prognosis in Kidney Renal Papillary Cell Carcinoma.
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Fecal Microbiota Transplantation Ameliorates Active Ulcerative Colitis by Downregulating Pro-inflammatory Cytokines in Mucosa and Serum.
Atractylenolide I Ameliorates Acetaminophen-Induced Acute Liver Injury via the TLR4/MAPKs/NF-κB Signaling Pathways.
Prevotella genus and its related NOD-like receptor signaling pathway in young males with stage III periodontitis.
Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p.
Drawn-on-Skin Sensors from Fully Biocompatible Inks toward High-Quality Electrophysiology.
Mesenchymal Stem Cell Exosomes Encapsulated Oral Microcapsules for Acute Colitis Treatment.
Integration of clinical and transcriptomics reveals programming of the lipid metabolism in gastric cancer.
Caulis Polygoni Multiflori Accelerates Megakaryopoiesis and Thrombopoiesis via Activating PI3K/Akt and MEK/ERK Signaling Pathways.
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Realgar Alleviated Neuroinflammation Induced by High Protein and High Calorie Diet in Rats via the Microbiota-Gut-Brain Axis.
Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome.
Synergistic anti-inflammatory effects of peimine, peiminine, and forsythoside a combination on LPS-induced acute lung injury by inhibition of the IL-17-NF-κB/MAPK pathway activation.
METTL3 Attenuates Inflammation in Fusarium solani-Induced Keratitis via the PI3K/AKT Signaling Pathway.
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
In vitro and in vivo effects of hyperglycemia and diabetes mellitus on nucleus pulposus cell senescence.
The protective mechanism of folic acid on hyperhomocysteinemia-related arterial injury in spontaneously hypertensive rats: Folic acid against arterial inflammation.
LipoxinA(4) analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia.
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Effects of BMAL1 on dentinogenic differentiation of dental pulp stem cells via PI3K/Akt/mTOR pathway.
P38α deficiency in macrophages ameliorates murine experimental colitis by regulating inflammation and immune process.
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin.
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification.
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration.
Desmethylbellidifolin Attenuates Dextran Sulfate Sodium-Induced Colitis: Impact on Intestinal Barrier, Intestinal Inflammation and Gut Microbiota.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Electroacupuncture attenuates brain injury through α7 nicotinic acetylcholine receptor-mediated suppression of neuroinflammation in a rat model of asphyxial cardiac arrest.
Effect of metformin in autistic BTBR T + Itpr3tf/J mice administered a high-fat diet.
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis.
Melatonin regulates the immune response and improves Sjögren's syndrome-like symptoms in NOD/Ltj Mice.
Maresin 1 alleviates sevoflurane-induced neuroinflammation in neonatal rats via JAK2/STAT3/IL-6 pathways.
Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion.
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
Polyphenols from the Peels of Punica granatum L. and Their Bioactivity of Suppressing Lipopolysaccharide-Stimulated Inflammatory Cytokines and Mediators in RAW 264.7 Cells via Activating p38 MAPK and NF-κB Signaling Pathways.
Synergistic Effects of Photobiomodulation Therapy with Combined Wavelength on Diabetic Wound Healing In Vitro and In Vivo.
RIPK3-Dependent Necroptosis Activates MCP-1-Mediated Inflammation in Mice after Intracerebral Hemorrhage.
Mechanisms of Dendrobium officinale polysaccharides in repairing gastric mucosal injuries based on mitogen-activated protein kinases (MAPK) signaling pathway.
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Sonodynamic Therapy Promotes Efferocytosis via CD47 Down-Regulation in Advanced Atherosclerotic Plaque.
Mussel-inspired adhesive gelatin-polyacrylamide hydrogel wound dressing loaded with tetracycline hydrochloride to enhance complete skin regeneration.
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Injectable gelatin/oxidized dextran hydrogel loaded with apocynin for skin tissue regeneration.
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Gastrodin ameliorates Concanavalin A-induced acute hepatitis via the IL6/JAK2/STAT3 pathway.
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation.
The Defenders of the Alveolus Succumb in COVID-19 Pneumonia to SARS-CoV-2, Necroptosis, Pyroptosis and Panoptosis.
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm.
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Targeting Vascular endothelial growth factor A with soluble vascular endothelial growth factor receptor 1 ameliorates nerve injury-induced neuropathic pain.
Multifunctional biomimetic hydrogel based on graphene nanoparticles and sodium alginate for peripheral nerve injury therapy.
MiR-92a/KLF4/p110δ regulates titanium particles-induced macrophages inflammation and osteolysis.
Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury.
LncRNA Malat-1 From MSCs-Derived Extracellular Vesicles Suppresses Inflammation and Cartilage Degradation in Osteoarthritis.
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer's Disease.
The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Si-Based Hydrogen-Producing Nanoagent Protects Fetuses From Miscarriage Caused by Mother-to-Child Transmission.
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury.
Chronic Voluntary Alcohol Drinking Causes Anxiety-like Behavior, Thiamine Deficiency, and Brain Damage of Female Crossed High Alcohol Preferring Mice.
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Regulatory T cells promote glioma cell stemness through TGF-β-NF-κB-IL6-STAT3 signaling.
Clinical significance of sarcoid-like reaction in lymph nodes of gastric cancer patients.
Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.
Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for treatment of moderate traumatic brain injury.
Role of Aberrantly Activated Lysophosphatidic Acid Receptor 1 Signaling Mediated Inflammation in Renal Aging.
Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity.
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Catalytically active gold clusters with atomic precision for noninvasive early intervention of neurotrauma.
Protective mechanisms of Agrimonia pilosa Ledeb in dextran sodium sulfate-induced colitis as determined by a network pharmacology approach.
Cancer-associated fibroblasts induce monocytic myeloid-derived suppressor cell generation via IL-6/exosomal miR-21-activated STAT3 signaling to promote cisplatin resistance in esophageal squamous cell carcinoma.
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
Mild hyperthermia promotes immune checkpoint blockade-based immunotherapy against metastatic pancreatic cancer using size-adjustable nanoparticles.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Elevated branched-chain α-keto acids exacerbate macrophage oxidative stress and chronic inflammatory damage in type 2 diabetes mellitus.
The role of TLR4/MyD88/NF-κB pathway in periodontitis-induced liver inflammation of rats.
Melatonin alleviates LPS-induced endoplasmic reticulum stress and inflammation in spermatogonial stem cells.
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Effects of carotid baroreceptor stimulation on aortic remodeling in obese rats.
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis.
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.
Alleviation of acute pancreatitis-associated lung injury by inhibiting the p38 mitogen-activated protein kinase pathway in pulmonary microvascular endothelial cells.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats.
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Cordyceps acid alleviates lung cancer in nude mice.
Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus.
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1.
Sanweidoukou decoction, a Chinese herbal formula, ameliorates β-amyloid protein-induced neuronal insult via modulating MAPK/NF-κB signaling pathways: Studies in vivo and in vitro.
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation.
Gancaonin N from Glycyrrhiza uralensis Attenuates the Inflammatory Response by Downregulating the NF-κB/MAPK Pathway on an Acute Pneumonia In Vitro Model.
WITHDRAWN: Immunohistochemical study of inflammatory responses in septa arising from type I intestinal atresia.
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization.
Shenyan Kangfu tablet alleviates diabetic kidney disease through attenuating inflammation and modulating the gut microbiota.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Evodiamine inhibits high-fat diet-induced colitis-associated cancer in mice through regulating the gut microbiota.
Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist.
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Suprabasin-derived bioactive peptides identified by plasma peptidomics.
Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats.
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Clinical and genomic characteristics of metabolic syndrome in colorectal cancer.
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Long-term ketamine administration induces bladder damage and upregulates autophagy-associated proteins in bladder smooth muscle tissue.
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
HIF1A-AS2 induces osimertinib resistance in lung adenocarcinoma patients by regulating the miR-146b-5p/IL-6/STAT3 axis.
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.
METTL3/N6-methyladenosine/ miR-21-5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF-κB pathway activation.
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Nr2e1 deficiency aggravates insulin resistance and chronic inflammation of visceral adipose tissues in a diet-induced obese mice model.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Dietary Ziziphus jujuba Fruit Attenuates Colitis-Associated Tumorigenesis: A Pivotal Role of the NF-κB/IL-6/JAK1/STAT3 Pathway.
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-[Formula: see text]B Signaling Pathway.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Huoxin Pill Attenuates Cardiac Inflammation by Suppression of TLR4/NF-κB in Acute Myocardial Ischemia Injury Rats.
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model.
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells.
ATP-Sensitive Potassium Channels Mediate the Cardioprotective Effect of Panax notoginseng Saponins against Myocardial Ischaemia-Reperfusion Injury and Inflammatory Reaction.
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Maternal 25-Hydroxyvitamin D Deficiency Promoted Metabolic Syndrome and Downregulated Nrf2/CBR1 Pathway in Offspring.
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
A Novel Antidiabetic Monomers Combination Alleviates Insulin Resistance Through Bacteria-Cometabolism-Inflammation Responses.
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Upregulated MELK Leads to Doxorubicin Chemoresistance and M2 Macrophage Polarization via the miR-34a/JAK2/STAT3 Pathway in Uterine Leiomyosarcoma.
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Dexmedetomidine ameliorates postoperative cognitive dysfunction by inhibiting Toll-like receptor 4 signaling in aged mice.
Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission.
Qingda granules attenuate hypertensive cardiac remodeling and inflammation in spontaneously hypertensive rats.
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies.
C/EBPγ is a critical negative regulator of LPS-/IgG immune complex-induced acute lung injury through the downregulation of C/EBPβ-/C/EBPδ-dependent C/EBP transcription activation.
Impact of chitosan membrane culture on the expression of pro- and anti-inflammatory cytokines in mesenchymal stem cells.
Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†.
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
CP-25 improves nephropathy in collagen-induced arthritis rats by inhibiting the renal inflammatory response.
Dihydroartemisinin prevents dextran sodium sulphate-induced colitisthrough inhibition of the activation of NLRP3 inflammasome and p38 MAPK signaling.
miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
Proinflammatory and regulatory mechanisms in allergic contact dermatitis caused by methylchloroisothiazolinone and methylisothiazolinone.
Chitosan-calcium alginate dressing promotes wound healing: A preliminary study.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.
Pterostilbene Ameliorates Glycemic Control, Dyslipidemia and Liver Injury in Type 2 Diabetes Rats.
Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission.
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis.
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats.
Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis.
Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved.
Chronotherapy targeting cytokine secretion attenuates collagen-induced arthritis in mice.
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury.
Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment.
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Supplementation of Inulin with Various Degree of Polymerization Ameliorates Liver Injury and Gut Microbiota Dysbiosis in High Fat-Fed Obese Mice.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
IL (Interleukin)-6 Contributes to Deep Vein Thrombosis and Is Negatively Regulated by miR-338-5p.
IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes.
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Polysaccharides from the Fleshy Fruits of Camellia oleifera Attenuate the Kidney Injury in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Disruption of retinoid homeostasis induces RBP4 overproduction in diabetes: O-GlcNAcylation involved.
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis.
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
MicroRNA-34a deficiency leads to impaired wound closure by augmented inflammation in mice.
COMP in the Infrapatellar Fat Pad-Results of a Prospective Histological, Immunohistological, and Biochemical Case-Control Study.
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment.
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6.
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
TLR4 gene in the regulation of periodontitis and its molecular mechanism.
Exploration of the mechanisms of Ge Gen Decoction against influenza A virus infection.
Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.
Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression.
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling.
M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis.
Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation.
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis.
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways.
Three kinds of corneal host cells contribute differently to corneal neovascularization.
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Upregulation of IL-6 in CUL4B-deficient myeloid-derived suppressive cells increases the aggressiveness of cancer cells.
Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway.
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Macrophage polarization in human gingival tissue in response to periodontal disease.
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Anti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy.
Inhibition of Fibroblast Growth Factor Receptor by AZD4547 Protects Against Inflammation in Septic Mice.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitis by regulating fatty acid degradation and microbial dysbiosis.
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage.
Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression.
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Curcumin inhibits cigarette smoke-induced inflammation via modulating the PPARγ-NF-κB signaling pathway.
Pigment epithelium-derived factor inhibits adipogenesis in 3T3-L1 adipocytes and protects against high-fat diet-induced obesity and metabolic disorders in mice.
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response.
MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma.
Bioactive Constituents from the Roots of Eurycoma longifolia.
Survival-time dependent increase in neuronal IL-6 and astroglial GFAP expression in fatally injured human brain tissue.
Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals.
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
The development of salt-sensitive hypertension regulated by PSGL-1 gene in mice.
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Lipocalin 2 Suppresses Ocular Inflammation by Inhibiting the Activation of NF-κβ Pathway in Endotoxin-Induced Uveitis.
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy.
TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Total glucosides of paeony improves the immunomodulatory capacity of MSCs partially via the miR-124/STAT3 pathway in oral lichen planus.
Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis.
Skeletal muscle secretion of IL-6 is muscle type specific: Ex vivo evidence.
Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer.
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala.
Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury.
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Ultraviolet B Inhibits IL-17A/TNF-α-Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts.
Effects of Ketamine on Levels of Inflammatory Cytokines IL-6, IL-1β, and TNF-α in the Hippocampus of Mice Following Acute or Chronic Administration.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Prognostic impact of interleukin-6 expression in stage I ovarian clear cell carcinoma.
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
The novel preventive effect of Daikenchuto (TJ-100), a Japanese herbal drug, against neonatal necrotizing enterocolitis in rats.
BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.
Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.
hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway.
Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer's disease.
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Diffuse large B cell lymphoma associated with chronic inflammation arising within atrial myxoma: aggressive histological features but indolent clinical behaviour.
Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Non-toxic retention of nanoceria in murine eyes.
Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide.
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy.
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
Elevated Level of Circulating Platelet-derived Microparticles in Oral Cancer.
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
MicroRNA-499 Rs3746444 polymorphism and biliary atresia.
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
hCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κB-Mediated Inflammatory Responses.
MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NF-κB Signaling Pathway Following Negative Regulation.
Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α-Dependent Senescence-Associated Secretory Phenotype.
The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells.
N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway.
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
Lv Z, Wang P, Li W, Xie Y, Sun W, Jin X, Jiang R, Fei Y, Liu Y, Shi T, Guo H, Sun Z, Lin J, Wang X, Tan G, Wu Y, Bao N, Shi D
Research (Washington, D.C.) 2024;7:0316
Research (Washington, D.C.) 2024;7:0316
Blocking SLC7A11 attenuates the proliferation of esophageal squamous cell carcinoma cells.
Li WT, Jin X, Song SJ, Wang C, Fu C, Jiang W, Bai J, Shi ZZ
Animal cells and systems 2024;28(1):237-250
Animal cells and systems 2024;28(1):237-250
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Liu X, Zhao W, Hu M, Zhang Y, Wang J, Zhang L
Iranian journal of basic medical sciences 2024;27(5):588-595
Iranian journal of basic medical sciences 2024;27(5):588-595
Exploring the Action Mechanism and Validation of the Key Pathways of Dendrobium officinale Throat-clearing Formula for the Treatment of Chronic Pharyngitis Based on Network Pharmacology.
Fang X, Jiang XF, Zhang YP, Zhou CL, Dong YJ, Bo-Li, Lv GY, Chen SH
Combinatorial chemistry & high throughput screening 2024;27(3):479-496
Combinatorial chemistry & high throughput screening 2024;27(3):479-496
Concomitant NAFLD Facilitates Liver Metastases and PD-1-Refractory by Recruiting MDSCs via CXCL5/CXCR2 in Colorectal Cancer.
Yang Y, Chen Y, Liu Z, Chang Z, Sun Z, Zhao L
Cellular and molecular gastroenterology and hepatology 2024;18(2):101351
Cellular and molecular gastroenterology and hepatology 2024;18(2):101351
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Zhao J, Zhao C, Xun T, Wang X, Wei S, Ye C, Zhang M, Guo D, Yang X
Drug design, development and therapy 2024;18:13-28
Drug design, development and therapy 2024;18:13-28
Unveiling the Mechanism of the ChaiShao Shugan Formula Against Triple-Negative Breast Cancer.
Fan T, Huang Y, Liu Z, Huang J, Ke B, Rong Y, Qiu H, Zhang B
Drug design, development and therapy 2024;18:1115-1131
Drug design, development and therapy 2024;18:1115-1131
MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts.
Jiang L, Li J, Ji K, Lei L, Li H
Journal of oral microbiology 2024;16(1):2292375
Journal of oral microbiology 2024;16(1):2292375
Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease.
Wang YH, Chen X, Bai YZ, Gao P, Yang Z, Guo Q, Lu YY, Zheng J, Liu D, Yang J, Tu PF, Zeng KW
Theranostics 2024;14(3):988-1009
Theranostics 2024;14(3):988-1009
Increased expression of in situ CD123 and reduced Toll-like receptor 7/9 signalling pathway suggest impaired activation of plasmacytoid dendritic cells in recurrent erythema multiforme.
Dias de Oliveira NF, Santi CG, Maruta CW, Miyamoto D, Pereira NV, Sotto MN, da Silva LFF, Aoki V
Journal of the European Academy of Dermatology and Venereology : JEADV 2024 Sep;38(9):e816-e819
Journal of the European Academy of Dermatology and Venereology : JEADV 2024 Sep;38(9):e816-e819
Untargeted serum and gastric metabolomics and network pharmacology analysis reveal the superior efficacy of zingiberis rhizoma recens-/euodiae fructus-processed Coptidis Rhizoma on gastric ulcer rats.
Zhang Z, Zheng Y, Zhang B, Wang R, Chen L, Wang Y, Feng W, Zheng X, Li K, Zhou N
Journal of ethnopharmacology 2024 Oct 5;332:118376
Journal of ethnopharmacology 2024 Oct 5;332:118376
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
Cao J, Yu X, Liu J, Fu J, Wang B, Wu C, Zhang S, Chen H, Wang Z, Xu Y, Sui T, Chang J, Cao X
Neural regeneration research 2024 Nov 1;19(11):2499-2512
Neural regeneration research 2024 Nov 1;19(11):2499-2512
Molecular mechanism of quercetin in treating RA-ILD based on network pharmacology, molecular docking, and experimental validation.
Wang J, Wang Z, Zhao Y, Bai L, Wei Y, Huang T, Xu Y, Zhou X
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092
Naunyn-Schmiedeberg's archives of pharmacology 2024 May;397(5):3077-3092
Vincamine alleviates brain injury by attenuating neuroinflammation and oxidative damage in a mouse model of Parkinson's disease through the NF-κB and Nrf2/HO-1 signaling pathways.
Wang P, Chen C, Shan M
Journal of biochemical and molecular toxicology 2024 May;38(5):e23714
Journal of biochemical and molecular toxicology 2024 May;38(5):e23714
Artificial nonenzymatic antioxidant Prussian blue/KGM-BSA nanocomposite hydrogel dressing as ROS scavenging for diabetic wound healing.
Tang DX, Liu K, Yang JY, Wang ZJ, Fu LL, Yang XJ, Li YS, Huang B, Liu Y
International journal of biological macromolecules 2024 May;266(Pt 1):131106
International journal of biological macromolecules 2024 May;266(Pt 1):131106
IL-6 Up-Regulates Expression of LIM-Domain Only Protein 4 in Psoriatic Keratinocytes through Activation of the MEK/ERK/NF-κB Pathway.
Tu Z, Wei W, Zeng F, Wang W, Zhang Y, Zhang Y, Zhou F, Cai C, Zhang S, Zhou H
The American journal of pathology 2024 May;194(5):708-720
The American journal of pathology 2024 May;194(5):708-720
Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2.
Zhou Z, Li Y, Wu S, Liu T, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116515
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116515
Rap1GAP exacerbates myocardial infarction by regulating the AMPK/SIRT1/NF-κB signaling pathway.
Shan T, Li X, Xie W, Wang S, Gao Y, Zheng Y, Su G, Li Y, Zhao Z
Cellular signalling 2024 May;117:111080
Cellular signalling 2024 May;117:111080
Morusin Alleviates Aortic Valve Calcification by Inhibiting Valve Interstitial Cell Senescence Through Ccnd1/Trim25/Nrf2 Axis.
Liu Z, Wang K, Jiang C, Chen Y, Liu F, Xie M, Yim WY, Yao D, Qian X, Chen S, Shi J, Xu K, Wang Y, Dong N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(20):e2307319
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(20):e2307319
Bioengineered Hydrogels Recapitulate Fibroblast Heterogeneity in Cancer.
Ho NCW, Yap JYY, Zhao Z, Wang Y, Fernando K, Li CH, Kwang XL, Quah HS, Arcinas C, Iyer NG, Fong ELS
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(20):e2307129
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(20):e2307129
Prevotella, a dominant bacterium in young people with stage Ⅲ periodontitis, related to the arachidonic acid metabolism pathway.
Ye Q, Zhao Y, Zhao J, Ouyang Z, Feng Y, Hu J, Su X, Chen N, Chen Y, Tan L, Feng Y, Guo Y
Microbes and infection 2024 May-Jun;26(4):105316
Microbes and infection 2024 May-Jun;26(4):105316
Chondroprotective effects of Apolipoprotein D in knee osteoarthritis mice through the PI3K/AKT/mTOR signaling pathway.
Zhang G, Huang C, Wang R, Guo J, Qin Y, Lv S
International immunopharmacology 2024 May 30;133:112005
International immunopharmacology 2024 May 30;133:112005
Transcriptomics-based identification of TYROBP and TLR8 as novel macrophage-related biomarkers for the diagnosis of acute rejection after kidney transplantation.
Pei J, Zhang J, Yu C, Luo J, Wen S, Hua Y, Wei G
Biochemical and biophysical research communications 2024 May 21;709:149790
Biochemical and biophysical research communications 2024 May 21;709:149790
Corneal Stroma Analysis and Related Ocular Manifestations in Recovered COVID-19 Patients.
Huang Y, Chen T, Chen X, Wan L, Hou X, Zhuang J, Jiang J, Li Y, Qiu J, Yu K, Zhuang J
Investigative ophthalmology & visual science 2024 May 1;65(5):14
Investigative ophthalmology & visual science 2024 May 1;65(5):14
Knee Osteotomy Decreases Joint Inflammation Based on Synovial Histology and Synovial Fluid Analysis.
Watanabe S, Matsushita T, Nishida K, Nagai K, Hoshino Y, Matsumoto T, Kuroda R
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2024 Mar;40(3):830-843
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2024 Mar;40(3):830-843
Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.
Che J, Wang H, Dong J, Wu Y, Zhang H, Fu L, Zhang J
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
CNS neuroscience & therapeutics 2024 Mar;30(3):e14454
M1 Macrophage-Derived Exosome LncRNA PVT1 Promotes Inflammation and Pyroptosis of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm by Inhibiting miR-186-5p and Regulating HMGB1.
Zhang J, Zhang X, Liu X, Chen H, Wang J, Ji M
Cardiovascular toxicology 2024 Mar;24(3):302-320
Cardiovascular toxicology 2024 Mar;24(3):302-320
Valproate attenuates somatic hyperalgesia induced by orofacial inflammation combined with stress through inhibiting spinal IL-6 and STAT1 phosphorylation.
Xu CX, Qiu XY, Guo Y, Xu TM, Traub RJ, Feng HN, Cao DY
Brain research bulletin 2024 Mar;208:110889
Brain research bulletin 2024 Mar;208:110889
Forsythiaside A attenuates mastitis via PINK1/Parkin-mediated mitophagy.
Liu J, Gao Y, Zhang H, Hao Z, Zhou G, Wen H, Su Q, Tong C, Yang X, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155358
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155358
Novel mechanism of Clostridium butyricum alleviated coprophagy prevention-induced intestinal inflammation in rabbit.
Li Z, He H, Chen M, Ni M, Guo C, Wan Z, Zhou J, Wang Z, Wang Y, Cai H, Li M, Sun H, Xu H
International immunopharmacology 2024 Mar 30;130:111773
International immunopharmacology 2024 Mar 30;130:111773
S100A9 aggravates early brain injury after subarachnoid hemorrhage via inducing neuroinflammation and inflammasome activation.
Wang G, Huang K, Tian Q, Guo Y, Liu C, Li Z, Yu Z, Zhang Z, Li M
iScience 2024 Mar 15;27(3):109165
iScience 2024 Mar 15;27(3):109165
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Chen B, Li YF, Fang Z, Cai WY, Tian ZQ, Li D, Wang ZM
Heliyon 2024 Mar 15;10(5):e27163
Heliyon 2024 Mar 15;10(5):e27163
Inhibition of PKM2 suppresses osteoclastogenesis and alleviates bone loss in mouse periodontitis.
Li F, Liu X, Li M, Wu S, Le Y, Tan J, Zhu C, Wan Q
International immunopharmacology 2024 Mar 10;129:111658
International immunopharmacology 2024 Mar 10;129:111658
Down-regulation of MKP-1 in hippocampus protects against stress-induced depression-like behaviors and neuroinflammation.
Geng M, Shao Q, Fu J, Gu J, Feng L, Zhao L, Liu C, Mu J, Zhang X, Zhao M, Guo X, Song C, Li Y, Wang H, Wang C
Translational psychiatry 2024 Mar 1;14(1):130
Translational psychiatry 2024 Mar 1;14(1):130
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Li B, Jiang XF, Dong YJ, Zhang YP, He XL, Zhou CL, Ding YY, Wang N, Wang YB, Cheng WQ, Jiang NH, Su J, Lv GY, Chen SH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis.
Wang YH, Gao P, Wang YQ, Xu LZ, Zeng KW, Tu PF
European journal of pharmacology 2024 Jun 5;972:176551
European journal of pharmacology 2024 Jun 5;972:176551
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Fei S, Ma Y, Zhou B, Chen X, Zhang Y, Yue K, Li Q, Gui Y, Xiang T, Liu J, Yang B, Wang L, Huang X
International journal of pharmaceutics 2024 Jun 25;659:124261
International journal of pharmaceutics 2024 Jun 25;659:124261
Forsythiaside A attenuates lipopolysaccharide-induced mouse mastitis by activating autophagy and regulating gut microbiota and metabolism.
Gao Y, Hao Z, Zhang H, Liu J, Zhou G, Wen H, Su Q, Tong C, Huang S, Wang X
Chemico-biological interactions 2024 Jun 1;396:111044
Chemico-biological interactions 2024 Jun 1;396:111044
Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/STAT3 signaling pathway.
Ran C, Lu M, Zhao F, Hao Y, Guo X, Li Y, Su Y, Wang H
Journal of ginseng research 2024 Jul;48(4):405-416
Journal of ginseng research 2024 Jul;48(4):405-416
Influence of METTL3 knockdown on PDLSC osteogenesis in E. coli LPS-induced inflammation.
Chen H, Peng L, Wang Z, He Y, Zhang X
Oral diseases 2024 Jul;30(5):3225-3238
Oral diseases 2024 Jul;30(5):3225-3238
Protective effects of Wenqingyin on sepsis-induced acute lung injury through regulation of the receptor for advanced glycation end products pathway.
Xie L, Zhang G, Wu Y, Hua Y, Ding W, Han X, Liu B, Zhou C, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155654
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155654
TERT activation targets DNA methylation and multiple aging hallmarks.
Shim HS, Iaconelli J, Shang X, Li J, Lan ZD, Jiang S, Nutsch K, Beyer BA, Lairson LL, Boutin AT, Bollong MJ, Schultz PG, DePinho RA
Cell 2024 Jul 25;187(15):4030-4042.e13
Cell 2024 Jul 25;187(15):4030-4042.e13
Ciliary neurotrophic factor promotes the development of homocysteine-induced vascular endothelial injury through inflammation mediated by the JAK2/STAT3 signaling pathway.
Zhang L, Xiang Y, Cao C, Tan J, Li F, Yang X
Experimental cell research 2024 Jul 1;440(1):114103
Experimental cell research 2024 Jul 1;440(1):114103
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
Pei X, Lou Y, Ren Q, Liu Y, Dai X, Ye M, Huang G, Cao J
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
An Q, Xia J, Pu F, Shi S
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Self-assembled and dynamic bond crosslinked herb-polysaccharide hydrogel with anti-inflammation and pro-angiogenesis effects for burn wound healing.
Wu H, Wang T, Liang Y, Chen L, Li Z
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113639
Colloids and surfaces. B, Biointerfaces 2024 Jan;233:113639
Betaine eliminates CFA-induced depressive-like behaviour in mice may be through inhibition of microglia and astrocyte activation and polarization.
Liang Y, Chen L, Huang Y, Xie L, Liu X, Zhou W, Cao W, Chen Z, Zhong X
Brain research bulletin 2024 Jan;206:110863
Brain research bulletin 2024 Jan;206:110863
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.
Chen C, Xu G, Chen J, Wu C, Zhang J, Jiang J, Hong H, Cui Z
Cellular signalling 2024 Jan;113:110942
Cellular signalling 2024 Jan;113:110942
The clock gene Bmal1 controls inflammatory mediators in rheumatoid arthritis fibroblast-like synoviocytes.
Kaneshiro K, Nakagawa K, Tsukamoto H, Matsuoka G, Okuno S, Tateishi K, Terashima Y, Shibanuma N, Yoshida K, Hashiramoto A
Biochemical and biophysical research communications 2024 Jan 8;691:149315
Biochemical and biophysical research communications 2024 Jan 8;691:149315
Jianpi Huayu Decoction suppresses cellular senescence in colorectal cancer via p53-p21-Rb pathway: Network pharmacology and in vivo validation.
Wang S, Xing Y, Wang R, Jin Z
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117347
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117347
A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.
Feng H, Yang L, Yang H, Cheng D, Li M, Song E, Xu T
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jan 3;32(1):218-226
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jan 3;32(1):218-226
The improvement of homocysteine-induced myocardial inflammation by vitamin D depends on activation of NFE2L2 mediated MTHFR.
Liu N, Su H, Lou Y, Kong J
International immunopharmacology 2024 Jan 25;127:111437
International immunopharmacology 2024 Jan 25;127:111437
Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells.
Blaszczak W, White B, Monterisi S, Swietach P
Cell reports 2024 Jan 23;43(1):113612
Cell reports 2024 Jan 23;43(1):113612
Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy.
Huang X, Deng Y, Xiao J, Wang H, Yang Q, Cao Z
Bioactive materials 2024 Feb;32:473-487
Bioactive materials 2024 Feb;32:473-487
Identification of differentially expressed genes associated with ferroptosis in Crohn's disease.
Zhang W, Li Z, Li H, Zhang D
Experimental and therapeutic medicine 2024 Feb;27(2):89
Experimental and therapeutic medicine 2024 Feb;27(2):89
IL-8 activates fibroblasts to promote the invasion of HNSCC cells via STAT3-MMP1.
Chen Y, Huang L, Gan RH, Yuan S, Lan T, Zheng D, Lu YG
Cell death discovery 2024 Feb 6;10(1):65
Cell death discovery 2024 Feb 6;10(1):65
Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation.
He Y, Liu F, He M, Long F, Hu D, Chen J, Fang M, Wang Z
BMC complementary medicine and therapies 2024 Feb 29;24(1):108
BMC complementary medicine and therapies 2024 Feb 29;24(1):108
FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion.
Zhao Z, Qin J, Qian Y, Huang C, Liu X, Wang N, Li L, Chao Y, Tan B, Zhang N, Qian M, Li D, Liu M, Du B
Journal of hematology & oncology 2024 Feb 24;17(1):9
Journal of hematology & oncology 2024 Feb 24;17(1):9
Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver.
Idelfonso-García OG, Alarcón-Sánchez BR, Guerrero-Escalera D, López-Hernández NA, Pérez-Hernández JL, Pacheco-Rivera R, Serrano-Luna J, Resendis-Antonio O, Muciño-Olmos EA, Aparicio-Bautista DI, Basurto-Islas G, Baltiérrez-Hoyos R, Vásquez-Garzón VR, Villa-Treviño S, Muriel P, Serrano H, Pérez-Carreón JI, Arellanes-Robledo J
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
Zhang Y, Tu S, Ji X, Wu J, Meng J, Gao J, Shao X, Shi S, Wang G, Qiu J, Zhang Z, Hua C, Zhang Z, Chen S, Zhang L, Zhu SJ
Nature communications 2024 Feb 13;15(1):1333
Nature communications 2024 Feb 13;15(1):1333
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Yang D, Wu W, Lu Q, Mou Y, Chen W, Wan S, Zhang M, Wang C, Du X, Li N, Hua J
Stress biology 2024 Feb 1;4(1):9
Stress biology 2024 Feb 1;4(1):9
NOD2 contributes to Parvimonas micra-induced bone resorption in diabetic rats with experimental periodontitis.
Chen YY, Tan L, Su XL, Chen NX, Liu Q, Feng YZ, Guo Y
Molecular oral microbiology 2024 Dec;39(6):446-460
Molecular oral microbiology 2024 Dec;39(6):446-460
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Li X, Li J, Ji J, Li S, Yao X, Fan H, Yao R
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Journal of neurochemistry 2024 Dec;168(12):3982-4000
A gelatin methacryloyl (GelMA) treated with gallic acid and coated with specially designed nanoparticles derived from ginseng enhances the healing of wounds in diabetic rats.
Yu YL, Zheng JC, Duan P, Cheng YN, Zhang H, Zheng L, Yu ZR, Xu JM, Hu HX, Pan ZY
International journal of biological macromolecules 2024 Aug;274(Pt 1):133372
International journal of biological macromolecules 2024 Aug;274(Pt 1):133372
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Dingyi L, Libin H, Jifeng P, Ding Z, Yulong L, Zhangyi W, Yunong Y, Qinghua W, Feng L
Experimental brain research 2024 Aug;242(8):1917-1932
Experimental brain research 2024 Aug;242(8):1917-1932
Ligation of cervical lymphatic vessels decelerates blood clearance and worsens outcomes after experimental subarachnoid hemorrhage.
Luo SQ, Gao SQ, Fei MX, Xue-Wang, Yan-Sun, Ran-Zhao, Han YL, Wang HD, Zhou ML
Brain research 2024 Aug 15;1837:148855
Brain research 2024 Aug 15;1837:148855
Single‐cell RNA sequencing reveals inflammatory retinal microglia in experimental autoimmune uveitis.
Liu J, Liao X, Li N, Xu Z, Yang W, Zhou H, Liu Y, Zhang Z, Wang G, Hou S
MedComm 2024 Apr;5(4):e534
MedComm 2024 Apr;5(4):e534
A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.
Shang S, Zhuang K, Chen J, Zhang M, Jiang S, Li W
Bioactive materials 2024 Apr;34:298-310
Bioactive materials 2024 Apr;34:298-310
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
Zhao C, Yu Y, Yin G, Xu C, Wang J, Wang L, Zhao G, Ni S, Zhang H, Zhou B, Wang Y
Inflammopharmacology 2024 Apr;32(2):1277-1294
Inflammopharmacology 2024 Apr;32(2):1277-1294
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Tan P, Cai S, Huang Z, Li M, Liu S, Chen J, Fu W, Zhao L
Cellular signalling 2024 Apr;116:111033
Cellular signalling 2024 Apr;116:111033
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361
Heliyon 2024 Apr 30;10(8):e29361
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Ding M, Zhu Y, Xu X, He H, Jiang T, Mo X, Wang Z, Yu W, Ou H
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Dong Y, Zhang Y, Li F, Tang B, Lv D, Wang H, Luo S
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Wu W, Jiang W, Zhou Y, Zhang Z, Li G, Tang C
Ecotoxicology and environmental safety 2024 Apr 15;275:116252
Ecotoxicology and environmental safety 2024 Apr 15;275:116252
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H(2)S generation.
Dilxat T, Shi Q, Chen X, Liu X
Aging 2024 Apr 12;16(7):6521-6536
Aging 2024 Apr 12;16(7):6521-6536
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Li LZ, Wang XM, Feng XJ, Liu K, Li B, Zhu LJ, Xu WF, Zheng X, Dong YJ, He XL, Guan HR, Ding YY, Wu HS, Zhou CJ, Ye SY, Zhang BB, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy.
Liu PL, Diao JY, Wang Q, Liu H, Zhang Y, Liang JQ, Zhang F, Liang XJ, Zhao HM
Analytical cellular pathology (Amsterdam) 2023;2023:7573165
Analytical cellular pathology (Amsterdam) 2023;2023:7573165
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Zhang J, Luan ZL, Huo XK, Zhang M, Morisseau C, Sun CP, Hammock BD, Ma XC
International journal of biological sciences 2023;19(1):294-310
International journal of biological sciences 2023;19(1):294-310
Intestinal edema induced by LPS-induced endotoxemia is associated with an inflammasome adaptor ASC.
Yamamoto T, Kurata M, Kaneko N, Masumoto J
PloS one 2023;18(2):e0281746
PloS one 2023;18(2):e0281746
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Wang M, Zhang Y, Liu M, Jia Y, He J, Xu X, Shi H, Zhang Y, Zhang J, Liu Y
Journal of Cancer 2023;14(4):611-627
Journal of Cancer 2023;14(4):611-627
A novel immunogenic cell death-related subtype classification and risk signature for predicting prognosis and immunotherapy efficacy in gastric cancer.
Dong B, Wu Y, Zhang J, Gu Y, Xie R, He X, Pang X, Wang X, Cui Y
Frontiers in immunology 2023;14:1162876
Frontiers in immunology 2023;14:1162876
PTPRC promoted CD8+ T cell mediated tumor immunity and drug sensitivity in breast cancer: based on pan-cancer analysis and artificial intelligence modeling of immunogenic cell death-based drug sensitivity stratification.
Li P, Wang W, Wang S, Cao G, Pan T, Huang Y, Wan H, Zhang W, Huang Y, Jin H, Wang Z
Frontiers in immunology 2023;14:1145481
Frontiers in immunology 2023;14:1145481
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Guo J, Zhou M, Zhao M, Li S, Fang Z, Li A, Zhang M
Frontiers in immunology 2023;14:1114620
Frontiers in immunology 2023;14:1114620
Suppression of tumorigenesis in LUAD by LRP1B through regulation of the IL-6-JAK-STAT3 pathway.
Ye C, Chong W, Liu Y, Zhu X, Ren H, Xu K, Xie X, Du F, Zhang Z, Wang M, Ma T, Shang L, Li L, Chen H
American journal of cancer research 2023;13(7):2886-2905
American journal of cancer research 2023;13(7):2886-2905
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Zhu Y, Wang T, Bao MJ, Qu XH, Li ZM
Frontiers in bioengineering and biotechnology 2023;11:1168136
Frontiers in bioengineering and biotechnology 2023;11:1168136
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Sanguisorba officinalis L. promotes diabetic wound healing in rats through inflammation response mediated by macrophage.
Song J, Zeng J, Zheng S, Jiang N, Wu A, Guo S, Ye R, Hu L, Huang F, Wang L, Xiaogang Z, Liu B, Wu J, Chen Q
Phytotherapy research : PTR 2023 Sep;37(9):4265-4281
Phytotherapy research : PTR 2023 Sep;37(9):4265-4281
Astragaloside IV attenuates high glucose-induced NF-κB-mediated inflammation through activation of PI3K/AKT-ERK-dependent Nrf2/ARE signaling pathway in glomerular mesangial cells.
Su X, Guo H, Zhou Y, Cao A, Shen Q, Zhu B, Yao X, Wang Y, Wang H, Wang L
Phytotherapy research : PTR 2023 Sep;37(9):4133-4148
Phytotherapy research : PTR 2023 Sep;37(9):4133-4148
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model.
Peng Y, Sun L, Guo W, Liu Z, Wang T, Zou T, Zhou J, Yang X, Fan X
Journal of pharmacological sciences 2023 Sep;153(1):46-54
Journal of pharmacological sciences 2023 Sep;153(1):46-54
Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.
Gong H, Han D, Luo Z, Zhu Q, Zhu X, Liu S, Chen D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154954
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154954
Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer.
Zi Y, Liu L, Gao J, Xu X, Guan Y, Rong Z, Cao Z, Li M, Zeng Z, Fan Q, Tang F, He J, Feng D, Chen J, Dai Y, Huang Y, Nie Y, Pei H, Cai Q, Li Z, Sun L, Deng Y
EMBO reports 2023 Sep 6;24(9):e55060
EMBO reports 2023 Sep 6;24(9):e55060
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Zhang Y, Zhang Y, Lei Y, Wu J, Kang Y, Zheng S, Shao L
Journal of hazardous materials 2023 Sep 5;457:131750
Journal of hazardous materials 2023 Sep 5;457:131750
Discovery of the Diphenyl 6-Oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide Analogue J27 for the Treatment of Acute Lung Injury and Sepsis by Targeting JNK2 and Inhibiting the JNK2-NF-κB/MAPK Pathway.
Liao J, Yang J, Li X, Hu C, Zhu W, Zhou Y, Zou Y, Guo M, Chen Z, Li X, Dai J, Xu Y, Zheng Z, Chen P, Cho WJ, Liang G, Tang Q
Journal of medicinal chemistry 2023 Sep 14;66(17):12304-12323
Journal of medicinal chemistry 2023 Sep 14;66(17):12304-12323
Inducible nitric oxide synthase activity mediates TNF-α-induced endothelial cell dysfunction.
Liu C, Lei S, Cai T, Cheng Y, Bai J, Fu W, Huang M
American journal of physiology. Cell physiology 2023 Sep 1;325(3):C780-C795
American journal of physiology. Cell physiology 2023 Sep 1;325(3):C780-C795
Ki67-targeted oncolytic adenovirus expressing IL-15 improves intratumoral T cell infiltration and PD-L1 expression in glioblastoma.
Zhang Q, Zhang J, Tian Y, Wang J, Jin G, Liu F
Virology 2023 Oct;587:109885
Virology 2023 Oct;587:109885
Fisetin treatment alleviates kidney injury in mice with diabetes-exacerbated atherosclerosis through inhibiting CD36/fibrosis pathway.
Zou TF, Liu ZG, Cao PC, Zheng SH, Guo WT, Wang TX, Chen YL, Duan YJ, Li QS, Liao CZ, Xie ZL, Han JH, Yang XX
Acta pharmacologica Sinica 2023 Oct;44(10):2065-2074
Acta pharmacologica Sinica 2023 Oct;44(10):2065-2074
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Novel pterostilbene derivatives ameliorate heart failure by reducing oxidative stress and inflammation through regulating Nrf2/NF-κB signaling pathway.
Yang X, Liu Z, Fang M, Zou T, Zhang Z, Meng X, Wang T, Meng H, Chen Y, Duan Y, Li Q
European journal of medicinal chemistry 2023 Oct 5;258:115602
European journal of medicinal chemistry 2023 Oct 5;258:115602
Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats.
Yu F, Xing C, Fan Y, Liu Y, Su P, Yang Q, Dong Y, Hou Y, Pan S
Diabetology & metabolic syndrome 2023 Oct 30;15(1):221
Diabetology & metabolic syndrome 2023 Oct 30;15(1):221
Anti-atherosclerotic effects of naringenin and quercetin from Folium Artemisiae argyi by attenuating Interleukin-1 beta (IL-1β)/ matrix metalloproteinase 9 (MMP9): network pharmacology-based analysis and validation.
Zhang L, Yang Z, Li X, Hua Y, Fan G, He F
BMC complementary medicine and therapies 2023 Oct 25;23(1):378
BMC complementary medicine and therapies 2023 Oct 25;23(1):378
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.
Zhang H, Gong J, Zhang S, Luo L, Luo C, Bi K, Wang L, Kan X, Tian Z, Wang X
Heliyon 2023 Nov;9(11):e21235
Heliyon 2023 Nov;9(11):e21235
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Xiao Y, Yuan Y, Yang Y, Liu B, Ding Z, Luo J, Chen S, Yu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
Chen L, Gu YJ, Zhang XG, Cheng L, Zhou MY, Yang Y, Wang Y
The Journal of physiology 2023 Nov;601(22):5107-5128
The Journal of physiology 2023 Nov;601(22):5107-5128
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Ma MH, Gao LL, Chen CB, Gu FL, Wu SQ, Li F, Han BX
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Disfunction of communication among immune cells in minimal-deviation adenocarcinoma of the cervix as an immunotherapeutic opportunity.
Zhang H, Liu C, Zhai X, Zhang Q, Zhou Y, Huang H, Ding M, Shi Q, Liu Y, Tang Y, Liu G, Wang H
International immunopharmacology 2023 Nov;124(Pt A):110907
International immunopharmacology 2023 Nov;124(Pt A):110907
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Ma Z, Ding Y, Ding X, Mou H, Mo R, Tan Q
Cell death discovery 2023 Nov 25;9(1):424
Cell death discovery 2023 Nov 25;9(1):424
Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer's Disease.
Li M, Yang H, Shao C, Liu Y, Wen S, Tang L
Microorganisms 2023 Nov 24;11(12)
Microorganisms 2023 Nov 24;11(12)
Sleep deprivation alleviates depression-like behaviors in mice via inhibiting immune and inflammatory pathways and improving neuroplasticity.
Shi S, Zhang M, Xie W, Ju P, Chen N, Wang F, Lyu D, Wang M, Hong W
Journal of affective disorders 2023 Nov 1;340:100-112
Journal of affective disorders 2023 Nov 1;340:100-112
Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid.
Huang L, Liu B, Yu XW, Pan GQ, Xu JY, Yan D, Wang YL, Guo QN
Environmental science and pollution research international 2023 May;30(22):62201-62212
Environmental science and pollution research international 2023 May;30(22):62201-62212
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Yu Y, Xia LK, Di Y, Nie QZ, Chen XL
Neural regeneration research 2023 May;18(5):1132-1138
Neural regeneration research 2023 May;18(5):1132-1138
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Polydopamine-Pd nanozymes as potent ROS scavengers in combination with near-infrared irradiation for osteoarthritis treatment.
Hu H, Yang J, Zhong Y, Wang J, Cai J, Luo C, Jin Z, Gao M, He M, Zheng L
iScience 2023 May 19;26(5):106605
iScience 2023 May 19;26(5):106605
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Yao B, Cai Y, Wang W, Deng J, Zhao L, Han Z, Wan L
Orthopaedic surgery 2023 Mar;15(3):858-867
Orthopaedic surgery 2023 Mar;15(3):858-867
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
Pei X, Zhang Z, Wang N, Huang G, Min X, Yang Y, Cao J
Bioorganic chemistry 2023 Mar;132:106351
Bioorganic chemistry 2023 Mar;132:106351
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Wang Q, Lei Z, Wang Z, Jiang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Mar 6;15(5)
Cancers 2023 Mar 6;15(5)
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury.
Zhang J, Zhang M, Huo XK, Ning J, Yu ZL, Morisseau C, Sun CP, Hammock BD, Ma XC
ACS central science 2023 Mar 22;9(3):440-456
ACS central science 2023 Mar 22;9(3):440-456
Effects of gradient high-field static magnetic fields on diabetic mice.
Yu B, Song C, Feng CL, Zhang J, Wang Y, Zhu YM, Zhang L, Ji XM, Tian XF, Cheng GF, Chen WL, Zablotskii V, Wang H, Zhang X
Zoological research 2023 Mar 18;44(2):249-258
Zoological research 2023 Mar 18;44(2):249-258
Metformin Attenuates the Inflammatory Response via the Regulation of Synovial M1 Macrophage in Osteoarthritis.
Zheng M, Zhu Y, Wei K, Pu H, Peng R, Xiao J, Liu C, Sun X
International journal of molecular sciences 2023 Mar 10;24(6)
International journal of molecular sciences 2023 Mar 10;24(6)
Role of the Peli1-RIPK1 Signaling Axis in Methamphetamine-Induced Neuroinflammation.
Xu W, Yang T, Lou X, Chen J, Wang X, Hu M, An D, Gao R, Wang J, Chen X
ACS chemical neuroscience 2023 Mar 1;14(5):864-874
ACS chemical neuroscience 2023 Mar 1;14(5):864-874
Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam.
Saletti PG, Mowrey WB, Liu W, Li Q, McCullough J, Aniceto R, Lin IH, Eklund M, Casillas-Espinosa PM, Ali I, Santana-Gomez C, Coles L, Shultz SR, Jones N, Staba R, O'Brien TJ, Moshé SL, Agoston DV, Galanopoulou AS, EpiBioS4Rx Study Group
Epilepsia open 2023 Jun;8(2):586-608
Epilepsia open 2023 Jun;8(2):586-608
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y
Nature biotechnology 2023 Jun;41(6):858-869
Nature biotechnology 2023 Jun;41(6):858-869
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Reversing inflammatory microenvironment by a single intra-articular injection of multi-stimulus responsive lipogel to relieve rheumatoid arthritis and promote joint repair.
Tao J, Yang P, Gao M, Zhang F, Wu Y, Jiang Y, Ning Y, Li Z, Ai F
Materials today. Bio 2023 Jun;20:100622
Materials today. Bio 2023 Jun;20:100622
RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury.
Liu PY, Chen CY, Lin YL, Lin CM, Tsai WC, Tsai YL, Lin GJ, Chen YG, Wang SY, Sun RN, Huang YC, Chang H, Chen YC
Cell death & disease 2023 Jun 21;14(6):369
Cell death & disease 2023 Jun 21;14(6):369
STING/TBK1 Regulates Inflammation in Macrophages and Titanium Particles-Induced Osteolysis.
Ouyang Z, Xu J, Liu T, Lin S, Sun Y, Huang Y, Zheng Z, Zeng G, Li C, Li S, Ding Y
ACS biomaterials science & engineering 2023 Jun 12;9(6):3273-3284
ACS biomaterials science & engineering 2023 Jun 12;9(6):3273-3284
Patrinia villosa treat colorectal cancer by activating PI3K/Akt signaling pathway.
Li XC, Wang S, Yang XX, Li TJ, Gu JX, Zhao L, Bao YR, Meng XS
Journal of ethnopharmacology 2023 Jun 12;309:116264
Journal of ethnopharmacology 2023 Jun 12;309:116264
Hydrogen sulfide attenuates TMAO‑induced macrophage inflammation through increased SIRT1 sulfhydration.
Liu MH, Lin XL, Xiao LL
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Cao X, Mao K, Zhang Y, Yang M, Liu H, Wang X, Hao L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113820
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113820
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Su W, Zheng X, Zhou H, Yang S, Zhu X
Molecular immunology 2023 Jul;159:46-57
Molecular immunology 2023 Jul;159:46-57
Dietary cholesterol drives the development of nonalcoholic steatohepatitis by altering gut microbiota mediated bile acid metabolism in high-fat diet fed mice.
Gao X, Lin X, Xin Y, Zhu X, Li X, Chen M, Huang Z, Guo H
The Journal of nutritional biochemistry 2023 Jul;117:109347
The Journal of nutritional biochemistry 2023 Jul;117:109347
Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease.
Shen ZB, Meng HW, Meng XS, Lv ZK, Fang MY, Zhang LL, Lv ZL, Li MS, Liu AK, Han JH, Li QS, Duan YJ
European journal of medicinal chemistry 2023 Jul 5;255:115417
European journal of medicinal chemistry 2023 Jul 5;255:115417
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Bai Y, Zhang L, Zheng B, Zhang X, Zhang H, Zhao A, Yu J, Yang Z, Wen J
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats.
Liu J, Cao C, Jin Y, Wang Y, Ma X, Li J, Guo S, Yang J, Niu J, Liang X
iScience 2023 Jul 21;26(7):107022
iScience 2023 Jul 21;26(7):107022
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome.
Xing J, Luo X, Jia K, Liu S, Chen S, Qiao G, Zhang C, Yi J
Journal of ovarian research 2023 Jul 1;16(1):128
Journal of ovarian research 2023 Jul 1;16(1):128
Akkermansia muciniphila protects mice against an emerging tick-borne viral pathogen.
Xie J, Li H, Zhang X, Yang T, Yue M, Zhang Y, Chen S, Cui N, Yuan C, Li J, Zhu SJ, Liu W
Nature microbiology 2023 Jan;8(1):91-106
Nature microbiology 2023 Jan;8(1):91-106
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Al-Raimi HAI, Kong J, Ran Y, Zhu L, Li J, Liu X, Yang X, Qi D, Liu T
Archives of medical research 2023 Jan;54(1):27-36
Archives of medical research 2023 Jan;54(1):27-36
Ginsenoside Rg1 alleviates learning and memory impairments and Aβ disposition through inhibiting NLRP1 inflammasome and autophagy dysfunction in APP/PS1 mice.
Li X, Huang L, Kong L, Su Y, Zhou H, Ji P, Sun R, Wang C, Li W, Li W
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Li M, Zhang Y, Han T, Guan L, Fan D, Wu Q, Liu J, Xu Y, Fan Y
Phytochemistry 2023 Jan;205:113487
Phytochemistry 2023 Jan;205:113487
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
Zhuang K, Tang H, Guo H, Yuan S
Microbial pathogenesis 2023 Jan;174:105937
Microbial pathogenesis 2023 Jan;174:105937
The significance of nanofiber polyglycolic acid for promoting tissue repair in a rat subcutaneous implantation model.
Sueyoshi Y, Niwa A, Nishikawa Y, Isogai N
Journal of biomedical materials research. Part B, Applied biomaterials 2023 Jan;111(1):16-25
Journal of biomedical materials research. Part B, Applied biomaterials 2023 Jan;111(1):16-25
Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis.
Zhang J, Lv G
Immunity, inflammation and disease 2023 Jan;11(1):e744
Immunity, inflammation and disease 2023 Jan;11(1):e744
Enzymatic one-pot preparation of carboxylmethyl chitosan-based hydrogel with inherent antioxidant and antibacterial properties for accelerating wound healing.
Wei Q, Ma J, Jia L, Zhao H, Dong Y, Jiang Y, Zhang W, Hu Z
International journal of biological macromolecules 2023 Jan 31;226:823-832
International journal of biological macromolecules 2023 Jan 31;226:823-832
Long-Term High-Fat Diet Consumption Induces Cognitive Decline Accompanied by Tau Hyper-Phosphorylation and Microglial Activation in Aging.
Liang Z, Gong X, Ye R, Zhao Y, Yu J, Zhao Y, Bao J
Nutrients 2023 Jan 3;15(1)
Nutrients 2023 Jan 3;15(1)
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Fan S, Weixuan W, Han H, Liansheng Z, Gang L, Jierui W, Yanshu Z
Chemico-biological interactions 2023 Jan 25;370:110310
Chemico-biological interactions 2023 Jan 25;370:110310
Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia.
Yan M, Jin H, Pan C, Han X
Molecular neurobiology 2023 Feb;60(2):884-900
Molecular neurobiology 2023 Feb;60(2):884-900
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Li Y, Yang L, Li J, Gao W, Zhao Z, Dong K, Duan W, Dai B, Guo R
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury.
Yang Y, Wang N, Xu L, Liu Y, Huang L, Gu M, Wu Y, Guo W, Sun H
Cell death & disease 2023 Feb 8;14(2):92
Cell death & disease 2023 Feb 8;14(2):92
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Li C, Zhang W, Chang X, Di X, Xie Q, Lin B, Zhang H, Ye Z, Lan M, Lian J, Zhang H, Qiu X, Zeng J, Huang M
Translational pediatrics 2023 Feb 28;12(2):194-207
Translational pediatrics 2023 Feb 28;12(2):194-207
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis Mixture on diabetic nephropathy.
Ma Y, Deng Y, Li N, Dong A, Li H, Chen S, Zhang S, Zhang M
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115768
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115768
Interleukin 6 promotes BMP9-induced osteoblastic differentiation through Stat3/mTORC1 in mouse embryonic fibroblasts.
Wang SY, Jiang JH, Liu SY, Zhang J, Gao X, Liu H, Ke KX, Jiang Y, Liu L, He BC
Aging 2023 Feb 1;15(3):718-733
Aging 2023 Feb 1;15(3):718-733
Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.
Yu B, Zhou M, Dong Z, Zheng H, Zhao Y, Zhou J, Zhang C, Wei F, Yu G, Liu WJ, Liu H, Wang Y
Pharmaceutical biology 2023 Dec;61(1):1222-1233
Pharmaceutical biology 2023 Dec;61(1):1222-1233
Resveratrol and its analogs suppress HIV replication, oxidative stress, and inflammation in macrophages.
Kumar S, Sinha N, Kodidela S, Godse S, Singla B, Singh UP, Bhat HK
NeuroImmune pharmacology and therapeutics 2023 Dec;2(4):365-374
NeuroImmune pharmacology and therapeutics 2023 Dec;2(4):365-374
An injectable and light curable hyaluronic acid composite gel with anti-biofilm, anti-inflammatory and pro-healing characteristics for accelerating infected wound healing.
Lin X, Fu T, Lei Y, Xu J, Wang S, He F, Xie Z, Zhang L
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127190
TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling.
Chen Y, Yin H, Sun J, Zhang G, Zhang Y, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115822
Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.
Hou L, Du Y
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884
The outer membrane protein of Fusobacterium necrophorum, 43K OMP, stimulates inflammatory cytokine production through nuclear factor kappa B activation.
He X, Liu J, Jiang K, Lian S, Shi Y, Fu S, Zhao P, Xiao J, Sun D, Guo D
Anaerobe 2023 Aug;82:102768
Anaerobe 2023 Aug;82:102768
M2 Macrophage Membrane-Mediated Biomimetic-Nanoparticle Carrying COX-siRNA Targeted Delivery for Prevention of Tendon Adhesions by Inhibiting Inflammation.
Sun J, Ju F, Jin J, Wang HL, Li ZJ, Sun YC, Chen QZ, Yang QQ, Tan J, Zhou YL
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(33):e2300326
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Feng DD, Chen JH, Chen YF, Cao Q, Li BJ, Chen XQ, Jin R, Zhou GP
Molecular immunology 2023 Aug;160:67-79
Molecular immunology 2023 Aug;160:67-79
STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD(+)-biosynthetic and consuming enzymes.
Murata H, Yasui Y, Oiso K, Ochi T, Tomonobu N, Yamamoto KI, Kinoshita R, Sakaguchi M
Cellular signalling 2023 Aug;108:110717
Cellular signalling 2023 Aug;108:110717
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y
Cellular signalling 2023 Aug;108:110712
Cellular signalling 2023 Aug;108:110712
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Yang X, Wang Q, Zhang X, Li L, Cao X, Zhou L, Huang Y, Sun G, Chen Y
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Repairing gastric ulcer with hyaluronic acid/extracellular matrix composite through promoting M2-type polarization of macrophages.
Ni R, Luo Y, Jiang L, Mao X, Feng Y, Tuersun S, Hu Z, Zhu Y
International journal of biological macromolecules 2023 Aug 1;245:125556
International journal of biological macromolecules 2023 Aug 1;245:125556
EEF1A2 accelerates the protein translation of chemokine in rat myocardial cells induced by ischemia-reperfusion.
Zhang ZJ, Sun ZX, Liu HJ
Heliyon 2023 Apr;9(4):e15305
Heliyon 2023 Apr;9(4):e15305
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury.
Zhang F, Ke C, Zhou Z, Xu K, Wang Y, Liu Y, Tu J
Planta medica 2023 Apr;89(5):493-507
Planta medica 2023 Apr;89(5):493-507
Up-regulation of PPAR-γ involved in the therapeutic effect of icariin on cigarette smoke-induced inflammation.
Li Q, Zhang H, Yan X, Zhao Z, Qiu J, Hu L, Jiang S, Kong Q, Sun J, Li L
Pulmonary pharmacology & therapeutics 2023 Apr;79:102197
Pulmonary pharmacology & therapeutics 2023 Apr;79:102197
Blockage of TRPV4 Downregulates the Nuclear Factor-Kappa B Signaling Pathway to Inhibit Inflammatory Responses and Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.
An D, Qi X, Li K, Xu W, Wang Y, Chen X, Sha S, Wu C, Du Y, Chen L
Cellular and molecular neurobiology 2023 Apr;43(3):1283-1300
Cellular and molecular neurobiology 2023 Apr;43(3):1283-1300
Regulatory T cells showed characteristics of T helper-17(Th17) cells in mice periodontitis model.
Kou Y, Jiang Y, Liu S, Yang P, Lu Y, Liu H, Li M
Oral diseases 2023 Apr;29(3):1149-1162
Oral diseases 2023 Apr;29(3):1149-1162
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Chen S, Lu K, Hou Y, You Z, Shu C, Wei X, Wu T, Shi N, Zhang G, Wu J, Chen S, Zhang L, Li W, Zhang D, Ju S, Chen M, Xu B
Journal for immunotherapy of cancer 2023 Apr;11(4)
Journal for immunotherapy of cancer 2023 Apr;11(4)
Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways.
Lu R, Wang YG, Qu Y, Wang SX, Peng C, You H, Zhu W, Chen A
Bone & joint research 2023 Apr 6;12(4):259-273
Bone & joint research 2023 Apr 6;12(4):259-273
Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages.
Cornwell A, Ziółkowski H, Badiei A
Biomolecules 2023 Apr 29;13(5)
Biomolecules 2023 Apr 29;13(5)
Inhibition of mGluR5 ameliorates lipid accumulation and inflammation in HepG2 cells.
Zeng S, Tao M, Yuan L, Zhang L, Luo X
Biochemical and biophysical research communications 2023 Apr 23;653:1-11
Biochemical and biophysical research communications 2023 Apr 23;653:1-11
Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer.
Mukhopadhyay S, Encarnación-Rosado J, Lin EY, Sohn ASW, Zhang H, Mancias JD, Kimmelman AC
Science advances 2023 Apr 21;9(16):eadf9284
Science advances 2023 Apr 21;9(16):eadf9284
Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling.
Liu H, Yan R, Xiao Z, Huang X, Yao J, Liu J, An G, Ge Y
Breast cancer research : BCR 2023 Apr 17;25(1):43
Breast cancer research : BCR 2023 Apr 17;25(1):43
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
SM22α Deletion Contributes to Neurocognitive Impairment in Mice through Modulating Vascular Smooth Muscle Cell Phenotypes.
Xu X, Liu XQ, Liu XL, Wang X, Zhang WD, Huang XF, Jia FY, Kong P, Han M
International journal of molecular sciences 2023 Apr 12;24(8)
International journal of molecular sciences 2023 Apr 12;24(8)
IL-7-Treated Periodontal Ligament Cells Regulate Local Immune Homeostasis by Modulating Treg/Th17 Cell Polarization.
Yu XY, Zhang ZQ, Huang JC, Lin JY, Cai XP, Liu CF
Frontiers in medicine 2022;9:754341
Frontiers in medicine 2022;9:754341
Orai1-mediated store-operated Ca(2+) entry promotes cervical cancer progression through IL-6 signaling.
Pan Y, Huang J, Liu K, Xie C, Chen H, Guo Z, Guo S, Chen Y
Frontiers in molecular biosciences 2022;9:1041674
Frontiers in molecular biosciences 2022;9:1041674
Experimental Periodontitis Deteriorates Cognitive Function and Impairs Insulin Signaling in a Streptozotocin-Induced Alzheimer's Disease Rat Model.
Duan L, Qian X, Wang Q, Huang L, Ge S
Journal of Alzheimer's disease : JAD 2022;88(1):57-74
Journal of Alzheimer's disease : JAD 2022;88(1):57-74
CIDEC: A Potential Factor in Diabetic Vascular Inflammation.
Song FQ, Zhou HM, Ma WX, Li YL, Hu BA, Shang YY, Wang ZH, Zhong M, Zhang W, Ti Y
Journal of vascular research 2022;59(2):114-123
Journal of vascular research 2022;59(2):114-123
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Huang ZW, Tan P, Yi XK, Chen H, Sun B, Shi H, Mou ZQ, Cheng YL, Li TX, Li Q, Fu WG
The American journal of Chinese medicine 2022;50(8):2185-2197
The American journal of Chinese medicine 2022;50(8):2185-2197
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S, Liu H, Wang B
Oxidative medicine and cellular longevity 2022;2022:8287227
Oxidative medicine and cellular longevity 2022;2022:8287227
Effects of Infrared Combined with Methylcobalamin on the Vibratory Sensory Threshold and Nerve Conduction Velocity of the Lower Extremity in Patients with Diabetic Foot Treatment.
Wang Y, Lin S, Chen Z, Chen Q, Fu M
Disease markers 2022;2022:8287192
Disease markers 2022;2022:8287192
DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status.
Dong X, Hu F, Yi J, Zhang Y, Liu C, Geng P, Duan H, Wu CT, Zhang X, Wang H
Stem cells international 2022;2022:7590337
Stem cells international 2022;2022:7590337
Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain.
Xi P, Mao R, Wu S, Liu L, Cai C, Lu L, Zhang C, Li Y
Mediators of inflammation 2022;2022:6010952
Mediators of inflammation 2022;2022:6010952
(-)-Epicatechin Reduces Neuroinflammation, Protects Mitochondria Function, and Prevents Cognitive Impairment in Sepsis-Associated Encephalopathy.
Ling J, Wu Y, Zou X, Chang Y, Li G, Fang M
Oxidative medicine and cellular longevity 2022;2022:2657713
Oxidative medicine and cellular longevity 2022;2022:2657713
The RNF26/CBX7 axis modulates the TNF pathway to promote cell proliferation and regulate sensitivity to TKIs in ccRCC.
Liu W, Wang H, Jian C, Li W, Ye K, Ren J, Zhu L, Wang Y, Jin X, Yi L
International journal of biological sciences 2022;18(5):2132-2145
International journal of biological sciences 2022;18(5):2132-2145
Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration.
Ding J, Shen L, Ye Y, Hu S, Ren Z, Liu T, Dai J, Li Z, Wang J, Luo Y, Zhang Q, Zhang X, Qi X, Huang J
Frontiers in molecular neuroscience 2022;15:861340
Frontiers in molecular neuroscience 2022;15:861340
Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines.
Yang QQ, Li HN, Xia YT, Tian X, Feng F, Yang J, Xu YL, Guo J, Li XQ, Wang JY, Zeng XY
Frontiers in molecular neuroscience 2022;15:820664
Frontiers in molecular neuroscience 2022;15:820664
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation.
Liu M, Peng Y, Che Y, Zhou M, Bai Y, Tang W, Huang S, Zhang B, Deng S, Wang C, Yu Z
Frontiers in pharmacology 2022;13:978587
Frontiers in pharmacology 2022;13:978587
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Chen Y, Li T, Tan P, Shi H, Cheng Y, Cai T, Bai J, Du Y, Fu W
Frontiers in pharmacology 2022;13:857015
Frontiers in pharmacology 2022;13:857015
Intra-Articular Injection of Adipose-Derived Stem Cells Ameliorates Pain and Cartilage Anabolism/Catabolism in Osteoarthritis: Preclinical and Clinical Evidences.
Yan B, Lv S, Tong P, Yan L, Chen Z, Zhou L, Yuan Q, Guo L, Shan L
Frontiers in pharmacology 2022;13:854025
Frontiers in pharmacology 2022;13:854025
A Novel Pyroptosis-Related Gene Signature for Predicting Prognosis in Kidney Renal Papillary Cell Carcinoma.
Hu J, Chen Y, Gao L, Ge C, Xie X, Lei P, Zhang Y, Liang P
Frontiers in genetics 2022;13:851384
Frontiers in genetics 2022;13:851384
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Xiang J, Zhang H, Zhou X, Wang D, Chen R, Tan W, Liang L, Shi M, Zhang F, Xiao Y, Zhou Y, Wang Y, Guo B
Frontiers in pharmacology 2022;13:819787
Frontiers in pharmacology 2022;13:819787
Fecal Microbiota Transplantation Ameliorates Active Ulcerative Colitis by Downregulating Pro-inflammatory Cytokines in Mucosa and Serum.
Zhang WH, Jin ZY, Yang ZH, Zhang JY, Ma XH, Guan J, Sun BL, Chen X
Frontiers in microbiology 2022;13:818111
Frontiers in microbiology 2022;13:818111
Atractylenolide I Ameliorates Acetaminophen-Induced Acute Liver Injury via the TLR4/MAPKs/NF-κB Signaling Pathways.
Du Z, Ma Z, Lai S, Ding Q, Hu Z, Yang W, Qian Q, Zhu L, Dou X, Li S
Frontiers in pharmacology 2022;13:797499
Frontiers in pharmacology 2022;13:797499
Prevotella genus and its related NOD-like receptor signaling pathway in young males with stage III periodontitis.
Zhao Y, Ye Q, Feng Y, Chen Y, Tan L, Ouyang Z, Zhao J, Hu J, Chen N, Su X, Dusenge MA, Feng Y, Guo Y
Frontiers in microbiology 2022;13:1049525
Frontiers in microbiology 2022;13:1049525
Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p.
Song JJ, Li H, Wang N, Zhou XY, Liu Y, Zhang Z, Feng Q, Chen YL, Liu D, Liang J, Ma XY, Wen XR, Fu YY
Frontiers in pharmacology 2022;13:1044375
Frontiers in pharmacology 2022;13:1044375
Drawn-on-Skin Sensors from Fully Biocompatible Inks toward High-Quality Electrophysiology.
Patel S, Ershad F, Lee J, Chacon-Alberty L, Wang Y, Morales-Garza MA, Haces-Garcia A, Jang S, Gonzalez L, Contreras L, Agarwal A, Rao Z, Liu G, Efimov IR, Zhang YS, Zhao M, Isseroff RR, Karim A, Elgalad A, Zhu W, Wu X, Yu C
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2107099
Small (Weinheim an der Bergstrasse, Germany) 2022 Sep;18(36):e2107099
Mesenchymal Stem Cell Exosomes Encapsulated Oral Microcapsules for Acute Colitis Treatment.
Gan J, Sun L, Chen G, Ma W, Zhao Y, Sun L
Advanced healthcare materials 2022 Sep;11(17):e2201105
Advanced healthcare materials 2022 Sep;11(17):e2201105
Integration of clinical and transcriptomics reveals programming of the lipid metabolism in gastric cancer.
Li Y, Zhao J, Chen R, Chen S, Xu Y, Cai W
BMC cancer 2022 Sep 6;22(1):955
BMC cancer 2022 Sep 6;22(1):955
Caulis Polygoni Multiflori Accelerates Megakaryopoiesis and Thrombopoiesis via Activating PI3K/Akt and MEK/ERK Signaling Pathways.
Yang X, Wang L, Zeng J, Wu A, Qin M, Wen M, Zhang T, Chen W, Mei Q, Qin D, Yang J, Jiang Y, Wu J
Pharmaceuticals (Basel, Switzerland) 2022 Sep 28;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 28;15(10)
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Cai X, Hua S, Deng J, Du Z, Zhang D, Liu Z, Khan NU, Zhou M, Chen Z
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Hu S, Shen P, Chen B, Tian SW, You Y
Neuroscience letters 2022 Sep 25;788:136850
Neuroscience letters 2022 Sep 25;788:136850
Realgar Alleviated Neuroinflammation Induced by High Protein and High Calorie Diet in Rats via the Microbiota-Gut-Brain Axis.
Feng C, Li A, Yin C, Wang S, Jin W, Liu Y, Huo T, Jiang H
Nutrients 2022 Sep 23;14(19)
Nutrients 2022 Sep 23;14(19)
Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome.
Zhang Y, Chen D, Wang D, Wang L, Weng Y, Wang H, Wu X, Wang Y
Journal of clinical medicine 2022 Sep 23;11(19)
Journal of clinical medicine 2022 Sep 23;11(19)
Synergistic anti-inflammatory effects of peimine, peiminine, and forsythoside a combination on LPS-induced acute lung injury by inhibition of the IL-17-NF-κB/MAPK pathway activation.
Liu C, Zhen D, Du H, Gong G, Wu Y, Ma Q, Quan ZS
Journal of ethnopharmacology 2022 Sep 15;295:115343
Journal of ethnopharmacology 2022 Sep 15;295:115343
METTL3 Attenuates Inflammation in Fusarium solani-Induced Keratitis via the PI3K/AKT Signaling Pathway.
Huang L, Tang H, Hu J
Investigative ophthalmology & visual science 2022 Sep 1;63(10):20
Investigative ophthalmology & visual science 2022 Sep 1;63(10):20
Carbon tetrachloride exposure induces ovarian damage through oxidative stress and inflammatory mediated ovarian fibrosis.
Xue L, Li X, Zhu X, Zhang J, Zhou S, Tang W, Chen D, Chen Y, Dai J, Wu M, Wu M, Wang S
Ecotoxicology and environmental safety 2022 Sep 1;242:113859
Ecotoxicology and environmental safety 2022 Sep 1;242:113859
In vitro and in vivo effects of hyperglycemia and diabetes mellitus on nucleus pulposus cell senescence.
Jiang Z, Jiang C, Jin L, Chen Z, Feng Z, Jiang X, Cao Y
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2022 Oct;40(10):2350-2361
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2022 Oct;40(10):2350-2361
The protective mechanism of folic acid on hyperhomocysteinemia-related arterial injury in spontaneously hypertensive rats: Folic acid against arterial inflammation.
Zhang L, Li Z, Xing C, Ma X, Xu R
Vascular 2022 Oct;30(5):988-998
Vascular 2022 Oct;30(5):988-998
LipoxinA(4) analog BML-111 protects podocytes cultured in high-glucose medium against oxidative injury via activating Nrf2 pathway.
Hao H, Xie F, Xu F, Wang Q, Wu Y, Zhang D
International immunopharmacology 2022 Oct;111:109170
International immunopharmacology 2022 Oct;111:109170
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Chen S, Qian S, Zhang L, Pan X, Qu F, Yu Y, Gu Z, Cui X, Shen H
International immunopharmacology 2022 Oct;111:109139
International immunopharmacology 2022 Oct;111:109139
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
Ramani K, Mavila N, Abeynayake A, Tomasi ML, Wang J, Matsuda M, Seki E
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Zhong X, Chen Z, Wang Y, Mao M, Deng Y, Shi M, Xu Y, Chen L, Cao W
Brain research bulletin 2022 Oct 15;189:174-183
Brain research bulletin 2022 Oct 15;189:174-183
Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia.
Zhou W, Wang C, Liu Z, Gou S
Journal of medicinal chemistry 2022 Oct 13;65(19):13436-13451
Journal of medicinal chemistry 2022 Oct 13;65(19):13436-13451
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Xiong L, Wu H, Zhong T, Luo F, Li Q, Li M, Fan Y
Antioxidants (Basel, Switzerland) 2022 Oct 12;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 12;11(10)
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Lin S, Li Q, Xu Z, Chen Z, Tao Y, Tong Y, Wang T, Chen S, Wang P
Psychopharmacology 2022 Nov;239(11):3657-3677
Psychopharmacology 2022 Nov;239(11):3657-3677
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Wang N, Yang Y, Liu Y, Huang L, Gu M, Wu Y, Xu L, Sun H, Guo W
International immunopharmacology 2022 Nov;112:109242
International immunopharmacology 2022 Nov;112:109242
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Zhan H, Pu Q, Long X, Lu W, Wang G, Meng F, Liao Z, Lan X, Chen M
Antioxidants (Basel, Switzerland) 2022 Nov 22;11(12)
Antioxidants (Basel, Switzerland) 2022 Nov 22;11(12)
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Dai HB, Wang HY, Wang FZ, Qian P, Gao Q, Zhou H, Zhou YB
Acta diabetologica 2022 May;59(5):661-673
Acta diabetologica 2022 May;59(5):661-673
Effects of BMAL1 on dentinogenic differentiation of dental pulp stem cells via PI3K/Akt/mTOR pathway.
Xu H, Zhao J, Chen G, Yuan Z, Liu J
International endodontic journal 2022 May;55(5):505-516
International endodontic journal 2022 May;55(5):505-516
P38α deficiency in macrophages ameliorates murine experimental colitis by regulating inflammation and immune process.
Chen W, Liang R, Yi Y, Zhu J, Zhang J
Pathology, research and practice 2022 May;233:153881
Pathology, research and practice 2022 May;233:153881
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Xiong T, Zheng X, Zhang K, Wu H, Dong Y, Zhou F, Cheng B, Li L, Xu W, Su J, Huang J, Jiang Z, Li B, Zhang B, Lv G, Chen S
Journal of ethnopharmacology 2022 May 10;289:115001
Journal of ethnopharmacology 2022 May 10;289:115001
Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Yang WX, Liu Y, Zhang SM, Wang HF, Liu YF, Liu JL, Li XH, Zeng MR, Han YZ, Liu FY, Sun L, Xiao L
Acta pharmacologica Sinica 2022 Mar;43(3):659-671
Acta pharmacologica Sinica 2022 Mar;43(3):659-671
Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin.
Wang L, Zhang T, Liu S, Mo Q, Jiang N, Chen Q, Yang J, Han YW, Chen JP, Huang FH, Li H, Zhou J, Luo JS, Wu JM
Pharmacological research 2022 Mar;177:106096
Pharmacological research 2022 Mar;177:106096
Injectable multifunctional CMC/HA-DA hydrogel for repairing skin injury.
Cui L, Li J, Guan S, Zhang K, Zhang K, Li J
Materials today. Bio 2022 Mar;14:100257
Materials today. Bio 2022 Mar;14:100257
Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification.
Jiang G, Sun C, Wang X, Mei J, Li C, Zhan H, Liao Y, Zhu Y, Mao J
Bioengineered 2022 Mar;13(3):5216-5235
Bioengineered 2022 Mar;13(3):5216-5235
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration.
Xu Z, Liu Y, Ma R, Chen J, Qiu J, Du S, Li C, Wu Z, Yang X, Chen Z, Chen T
ACS applied materials & interfaces 2022 Mar 30;14(12):14059-14071
ACS applied materials & interfaces 2022 Mar 30;14(12):14059-14071
Desmethylbellidifolin Attenuates Dextran Sulfate Sodium-Induced Colitis: Impact on Intestinal Barrier, Intestinal Inflammation and Gut Microbiota.
Wu J, Wu Y, Chen Y, Liu M, Yu H, Zhang Y, Wang T
Planta medica 2022 Jun;88(7):559-569
Planta medica 2022 Jun;88(7):559-569
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Wang Z, Liang M, Liu B, Yang L
Food science and biotechnology 2022 Jun;31(6):745-758
Food science and biotechnology 2022 Jun;31(6):745-758
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Zhong T, Li M, Wu H, Wang D, Liu J, Xu Y, Fan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Qian P, Wang Q, Wang FZ, Dai HB, Wang HY, Gao Q, Zhou H, Zhou YB
Pharmaceuticals (Basel, Switzerland) 2022 Jun 6;15(6)
Pharmaceuticals (Basel, Switzerland) 2022 Jun 6;15(6)
Electroacupuncture attenuates brain injury through α7 nicotinic acetylcholine receptor-mediated suppression of neuroinflammation in a rat model of asphyxial cardiac arrest.
Liu Y, Zhang L, Han R, Bai W, Li J, Gao C
Journal of neuroimmunology 2022 Jun 15;367:577873
Journal of neuroimmunology 2022 Jun 15;367:577873
Effect of metformin in autistic BTBR T + Itpr3tf/J mice administered a high-fat diet.
Deng W, Li F, Ke H, Wang S, Li Z, Lv P, Chen Y
Brain research bulletin 2022 Jun 1;183:172-183
Brain research bulletin 2022 Jun 1;183:172-183
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation.
Wang Y, Xie W, Feng Y, Xu Z, He Y, Xiong Y, Chen L, Li X, Liu J, Liu G, Wu Q
International journal of molecular medicine 2022 Jul;50(1)
International journal of molecular medicine 2022 Jul;50(1)
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis.
Lee WR, Chou WL, Lin ZC, Sung CT, Lin CY, Fang JY
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:590-606
Journal of controlled release : official journal of the Controlled Release Society 2022 Jul;347:590-606
Melatonin regulates the immune response and improves Sjögren's syndrome-like symptoms in NOD/Ltj Mice.
Liu Y, Weng X, Wei M, Yu S, Ding Y, Cheng B
Biochemical pharmacology 2022 Jul;201:115073
Biochemical pharmacology 2022 Jul;201:115073
Maresin 1 alleviates sevoflurane-induced neuroinflammation in neonatal rats via JAK2/STAT3/IL-6 pathways.
Wu Y, Sun Z, Wang T, Wang Y, Zhong L, Kong F
International immunopharmacology 2022 Jul;108:108912
International immunopharmacology 2022 Jul;108:108912
Diminished miR-374c-5p negatively regulates IL (interleukin)-6 in unexplained recurrent spontaneous abortion.
Zhao L, Han L, Hei G, Wei R, Zhang Z, Zhu X, Guo Q, Chu C, Fu X, Xu K, Li X
Journal of molecular medicine (Berlin, Germany) 2022 Jul;100(7):1043-1056
Journal of molecular medicine (Berlin, Germany) 2022 Jul;100(7):1043-1056
Transcriptional landscape of human neuroblastoma cells in response to SARS-CoV-2.
Yang RC, Huang K, Zhang HP, Li L, Tan C, Chen HC, Jin ML, Wang XR
BMC neuroscience 2022 Jul 6;23(1):43
BMC neuroscience 2022 Jul 6;23(1):43
Polyphenols from the Peels of Punica granatum L. and Their Bioactivity of Suppressing Lipopolysaccharide-Stimulated Inflammatory Cytokines and Mediators in RAW 264.7 Cells via Activating p38 MAPK and NF-κB Signaling Pathways.
Li HM, Kouye O, Yang DS, Zhang YQ, Ruan JY, Han LF, Zhang Y, Wang T
Molecules (Basel, Switzerland) 2022 Jul 20;27(14)
Molecules (Basel, Switzerland) 2022 Jul 20;27(14)
Synergistic Effects of Photobiomodulation Therapy with Combined Wavelength on Diabetic Wound Healing In Vitro and In Vivo.
Cai W, Hamushan M, Zhang Y, Xu Z, Ren Z, Du J, Ju J, Cheng P, Tan M, Han P
Photobiomodulation, photomedicine, and laser surgery 2022 Jan;40(1):13-24
Photobiomodulation, photomedicine, and laser surgery 2022 Jan;40(1):13-24
RIPK3-Dependent Necroptosis Activates MCP-1-Mediated Inflammation in Mice after Intracerebral Hemorrhage.
Huang S, Hu W, Rao D, Wu X, Bai Q, Wang J, Chu Z, Xu Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Jan;31(1):106213
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Jan;31(1):106213
Mechanisms of Dendrobium officinale polysaccharides in repairing gastric mucosal injuries based on mitogen-activated protein kinases (MAPK) signaling pathway.
Ma S, Wu Q, Zhao Z, Xiong J, Niu J, Liu C, Liu T, Chai Y, Qu X, Ma Z, Zhang L, Pu X
Bioengineered 2022 Jan;13(1):71-82
Bioengineered 2022 Jan;13(1):71-82
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Wang L, Zhang D, Ren Y, Guo S, Li J, Ma S, Yao M, Guan F
Materials today. Bio 2022 Jan;13:100201
Materials today. Bio 2022 Jan;13:100201
Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism.
Wang X, Du H, Li X
International immunopharmacology 2022 Jan;102:108413
International immunopharmacology 2022 Jan;102:108413
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Wu Y, Zhao L, Gu L, Tilyek A, Yu B, Chai C
Journal of ethnopharmacology 2022 Jan 30;283:114696
Journal of ethnopharmacology 2022 Jan 30;283:114696
Sonodynamic Therapy Promotes Efferocytosis via CD47 Down-Regulation in Advanced Atherosclerotic Plaque.
Cao Y, Yao J, Gao W, Cao Z, Diabakte K, Wang L, Sun X, Tian Y
International heart journal 2022 Jan 29;63(1):131-140
International heart journal 2022 Jan 29;63(1):131-140
Mussel-inspired adhesive gelatin-polyacrylamide hydrogel wound dressing loaded with tetracycline hydrochloride to enhance complete skin regeneration.
Wang Y, Xiao D, Quan L, Chai H, Sui X, Wang B, Xu H, Mao Z
Soft matter 2022 Jan 19;18(3):662-674
Soft matter 2022 Jan 19;18(3):662-674
Isoliquiritigenin attenuates neuroinflammation in mice model of Parkinson's disease by promoting Nrf2/NQO-1 pathway.
Huang L, Han Y, Zhou Q, Sun Z, Yan J
Translational neuroscience 2022 Jan 1;13(1):301-308
Translational neuroscience 2022 Jan 1;13(1):301-308
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153845
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Wang L, Wang X, Kong L, Li Y, Huang K, Wu J, Wang C, Sun H, Sun P, Gu J, Luo H, Liu K, Meng Q
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Phytotherapy research : PTR 2022 Feb;36(2):899-913
Injectable gelatin/oxidized dextran hydrogel loaded with apocynin for skin tissue regeneration.
Guan S, Zhang K, Cui L, Liang J, Li J, Guan F
Biomaterials advances 2022 Feb;133:112604
Biomaterials advances 2022 Feb;133:112604
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2022 Feb;132(2):1370-1383
Journal of applied microbiology 2022 Feb;132(2):1370-1383
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Xu M, Ren L, Fan J, Huang L, Zhou L, Li X, Ye X
Life sciences 2022 Feb 1;290:120266
Life sciences 2022 Feb 1;290:120266
Morin Inhibits Dox-Induced Vascular Inflammation By Regulating PTEN/AKT/NF-κB Pathway.
Yu J, Qi HL, Zhang H, Zhao ZY, Jing-Zhao, Nie ZY
Inflammation 2022 Dec;45(6):2406-2418
Inflammation 2022 Dec;45(6):2406-2418
Gastrodin ameliorates Concanavalin A-induced acute hepatitis via the IL6/JAK2/STAT3 pathway.
Zhou Y, Chen J, Yao Z, Gu X
Immunopharmacology and immunotoxicology 2022 Dec;44(6):925-934
Immunopharmacology and immunotoxicology 2022 Dec;44(6):925-934
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Cai W, Zhang Y, Jin W, Wei S, Chen J, Zhong C, Zhong Y, Tu C, Peng H
International immunopharmacology 2022 Dec;113(Pt A):109336
International immunopharmacology 2022 Dec;113(Pt A):109336
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
Zhang M, Zhang J, Wang C, Yan JK, Yi J, Ning J, Huo XK, Yu ZL, Zhang BJ, Sun CP, Ma XC
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15104-15115
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15104-15115
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247
Biomaterials science 2022 Dec 20;11(1):235-247
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Xin Y, Wang J, Chu T, Zhou Y, Liu C, Xu A
Brain sciences 2022 Dec 17;12(12)
Brain sciences 2022 Dec 17;12(12)
Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.
Wang Y, Xiong B, Lin H, Li Q, Yang H, Qiao Y, Li Q, Xu Z, Lyu W, Qu W, Liu W, Chen Y, Feng F, Sun H
European journal of medicinal chemistry 2022 Dec 15;244:114806
European journal of medicinal chemistry 2022 Dec 15;244:114806
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Feng XW, Cheng QL, Fang L, Liu WY, Liu LW, Sun CQ, Lu ZH, Li GM, Gu RZ
Journal of food biochemistry 2022 Aug;46(8):e14162
Journal of food biochemistry 2022 Aug;46(8):e14162
Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation.
Huang L, Chen J, Li X, Huang M, Liu J, Qin N, Zeng Z, Wang X, Li F, Yang H
The Journal of surgical research 2022 Aug;276:379-393
The Journal of surgical research 2022 Aug;276:379-393
The Defenders of the Alveolus Succumb in COVID-19 Pneumonia to SARS-CoV-2, Necroptosis, Pyroptosis and Panoptosis.
Schifanella L, Anderson J, Wieking G, Southern PJ, Antinori S, Galli M, Corbellino M, Lai A, Klatt N, Schacker TW, Haase AT
bioRxiv : the preprint server for biology 2022 Aug 8;
bioRxiv : the preprint server for biology 2022 Aug 8;
Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.
Zhang Q, Luo P, Xia F, Tang H, Chen J, Zhang J, Liu D, Zhu Y, Liu Y, Gu L, Zheng L, Li Z, Yang F, Dai L, Liao F, Xu C, Wang J
Cell chemical biology 2022 Aug 18;29(8):1248-1259.e6
Cell chemical biology 2022 Aug 18;29(8):1248-1259.e6
Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm.
Zhou WX, Wang S, Wu TC, Cheng LC, Du Y, Wu W, Lin C, Li XY, Hu ZL
Journal of translational medicine 2022 Aug 16;20(1):368
Journal of translational medicine 2022 Aug 16;20(1):368
CoQ10 Improves Myocardial Damage in Doxorubicin-Induced Heart Failure in C57BL/6 Mice.
Pei Z, Ma L, Li Y, Yang J, Yang Q, Yao W, Li S
Frontiers in bioscience (Landmark edition) 2022 Aug 15;27(8):244
Frontiers in bioscience (Landmark edition) 2022 Aug 15;27(8):244
Gut-Flora-Dependent Metabolite Trimethylamine-N-Oxide Promotes Atherosclerosis-Associated Inflammation Responses by Indirect ROS Stimulation and Signaling Involving AMPK and SIRT1.
Zhou S, Xue J, Shan J, Hong Y, Zhu W, Nie Z, Zhang Y, Ji N, Luo X, Zhang T, Ma W
Nutrients 2022 Aug 15;14(16)
Nutrients 2022 Aug 15;14(16)
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Targeting Vascular endothelial growth factor A with soluble vascular endothelial growth factor receptor 1 ameliorates nerve injury-induced neuropathic pain.
Peng Z, Yang F, Huang S, Tang Y, Wan L
Molecular pain 2022 Apr;18:17448069221094528
Molecular pain 2022 Apr;18:17448069221094528
Multifunctional biomimetic hydrogel based on graphene nanoparticles and sodium alginate for peripheral nerve injury therapy.
Jin Y, Zhang W, Zhang Y, Yang Y, Fang Z, Song J, Qian Y, Yuan WE
Biomaterials advances 2022 Apr;135:212727
Biomaterials advances 2022 Apr;135:212727
MiR-92a/KLF4/p110δ regulates titanium particles-induced macrophages inflammation and osteolysis.
Wen Z, Lin S, Li C, Ouyang Z, Chen Z, Li S, Huang Y, Luo W, Zheng Z, Guo P, Kuang M, Ding Y
Cell death discovery 2022 Apr 13;8(1):197
Cell death discovery 2022 Apr 13;8(1):197
Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury.
Gong F, Ge T, Liu J, Xiao J, Wu X, Wang H, Zhu Y, Xia D, Hu B
Aging 2022 Apr 10;14(7):3216-3232
Aging 2022 Apr 10;14(7):3216-3232
LncRNA Malat-1 From MSCs-Derived Extracellular Vesicles Suppresses Inflammation and Cartilage Degradation in Osteoarthritis.
Pan C, Huang W, Chen Q, Xu J, Yao G, Li B, Wu T, Yin C, Cheng X
Frontiers in bioengineering and biotechnology 2021;9:772002
Frontiers in bioengineering and biotechnology 2021;9:772002
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Xu J, Xu H, Ma K, Wang Y, Niu B, Zhang L, Li F
Frontiers in cell and developmental biology 2021;9:618045
Frontiers in cell and developmental biology 2021;9:618045
Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer's Disease.
Qian X, Zhang S, Duan L, Yang F, Zhang K, Yan F, Ge S
Journal of Alzheimer's disease : JAD 2021;79(4):1785-1800
Journal of Alzheimer's disease : JAD 2021;79(4):1785-1800
The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer.
Zhou L, Gu W, Kui F, Gao F, Niu Y, Li W, Zhang Y, Guo L, Wang J, Guo Z, Du G
Food & nutrition research 2021;65
Food & nutrition research 2021;65
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Si-Based Hydrogen-Producing Nanoagent Protects Fetuses From Miscarriage Caused by Mother-to-Child Transmission.
Usui N, Togawa S, Sumi T, Kobayashi Y, Koyama Y, Nakamura Y, Kondo M, Shinoda K, Kobayashi H, Shimada S
Frontiers in medical technology 2021;3:665506
Frontiers in medical technology 2021;3:665506
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Li Y, Chandra TP, Song X, Nie L, Liu M, Yi J, Zheng X, Chu C, Yang J
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction.
Tan J, Dai A, Pan L, Zhang L, Wang Z, Ke T, Sun W, Wu Y, Ding PH, Chen L
Journal of immunology research 2021;2021:9919024
Journal of immunology research 2021;2021:9919024
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
Zhang J, Cheng P, Dai W, Ji J, Wu L, Feng J, Wu J, Yu Q, Li J, Guo C
PPAR research 2021;2021:6658944
PPAR research 2021;2021:6658944
H2O2 gel bleaching induces cytotoxicity and pain conduction in dental pulp stem cells via intracellular reactive oxygen species on enamel/dentin disc.
Chen C, Huang X, Zhu W, Ding C, Huang P, Li R
PloS one 2021;16(9):e0257221
PloS one 2021;16(9):e0257221
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Wang FZ, Wei WB, Li X, Huo JY, Jiang WY, Wang HY, Qian P, Li ZZ, Zhou YB
American journal of translational research 2021;13(9):10950-10961
American journal of translational research 2021;13(9):10950-10961
Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury.
Ma H, Liu J, Du Y, Zhang S, Cao W, Jia Z, Gong W, Zhang A
Frontiers in pharmacology 2021;12:626166
Frontiers in pharmacology 2021;12:626166
Chronic Voluntary Alcohol Drinking Causes Anxiety-like Behavior, Thiamine Deficiency, and Brain Damage of Female Crossed High Alcohol Preferring Mice.
Xu H, Li H, Liu D, Wen W, Xu M, Frank JA, Chen J, Zhu H, Grahame NJ, Luo J
Frontiers in pharmacology 2021;12:614396
Frontiers in pharmacology 2021;12:614396
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Chen L, Zhong X, Cao W, Mao M, Li W, Yang H, Li M, Shi M, Zhang Y, Deng Y, Zu X, Liu J
Frontiers in immunology 2021;12:609319
Frontiers in immunology 2021;12:609319
Regulatory T cells promote glioma cell stemness through TGF-β-NF-κB-IL6-STAT3 signaling.
Liu S, Zhang C, Wang B, Zhang H, Qin G, Li C, Cao L, Gao Q, Ping Y, Zhang K, Lian J, Zhao Q, Wang D, Zhang Z, Zhao X, Yang L, Huang L, Yang B, Zhang Y
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2601-2616
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2601-2616
Clinical significance of sarcoid-like reaction in lymph nodes of gastric cancer patients.
Itai Y, Ueda Y, Etoh T, Shirasaka Y, Shiroshita H, Shiraishi N, Daa T, Inomata M
Journal of surgical oncology 2021 Sep;124(3):293-300
Journal of surgical oncology 2021 Sep;124(3):293-300
Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.
Zong RR, Zhu FF, Han W, Wang YX, Wang GL, Wang YZ, Mao YB, Guan TJ, Liu ZG, Xue YH, Li C
Journal of proteomics 2021 Sep 30;248:104351
Journal of proteomics 2021 Sep 30;248:104351
Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for treatment of moderate traumatic brain injury.
Li J, Zhang D, Guo S, Zhao C, Wang L, Ma S, Guan F, Yao M
International journal of biological macromolecules 2021 Sep 30;187:200-213
International journal of biological macromolecules 2021 Sep 30;187:200-213
Role of Aberrantly Activated Lysophosphatidic Acid Receptor 1 Signaling Mediated Inflammation in Renal Aging.
Jin Y, Kim EN, Lim JH, Kim HD, Ban TH, Yang CW, Park CW, Choi BS
Cells 2021 Sep 28;10(10)
Cells 2021 Sep 28;10(10)
Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway.
Cheng J, Hao J, Jiang X, Ji J, Wu T, Chen X, Zhang F
International immunopharmacology 2021 Oct;99:108006
International immunopharmacology 2021 Oct;99:108006
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity.
Tung YT, Zeng JL, Ho ST, Xu JW, Li S, Wu JH
Antioxidants (Basel, Switzerland) 2021 Oct 27;10(11)
Antioxidants (Basel, Switzerland) 2021 Oct 27;10(11)
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Zhao K, Zhang J, Xu T, Yang C, Weng L, Wu T, Wu X, Miao J, Guo X, Tu J, Zhang D, Zhou B, Sun W, Kong X
Journal of Zhejiang University. Science. B 2021 Oct 15;22(10):818-838
Journal of Zhejiang University. Science. B 2021 Oct 15;22(10):818-838
Catalytically active gold clusters with atomic precision for noninvasive early intervention of neurotrauma.
Zhang Y, Sun S, Liu H, Ren Q, Hao W, Xin Q, Xu J, Wang H, Zhang XD
Journal of nanobiotechnology 2021 Oct 13;19(1):319
Journal of nanobiotechnology 2021 Oct 13;19(1):319
Protective mechanisms of Agrimonia pilosa Ledeb in dextran sodium sulfate-induced colitis as determined by a network pharmacology approach.
Li C, Wang M, Sui J, Zhou Y, Chen W
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1342-1353
Acta biochimica et biophysica Sinica 2021 Oct 12;53(10):1342-1353
Cancer-associated fibroblasts induce monocytic myeloid-derived suppressor cell generation via IL-6/exosomal miR-21-activated STAT3 signaling to promote cisplatin resistance in esophageal squamous cell carcinoma.
Zhao Q, Huang L, Qin G, Qiao Y, Ren F, Shen C, Wang S, Liu S, Lian J, Wang D, Yu W, Zhang Y
Cancer letters 2021 Oct 10;518:35-48
Cancer letters 2021 Oct 10;518:35-48
miR-128 participates in the pathogenesis of chronic constipation by regulating the p38α/M-CSF inflammatory signaling pathway.
Hong Y, Ren X, Liu W, Sun K, Chen B, Liu B, Yu X, Chen Q, Qian Q, Xie X, Jiang C
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447
American journal of physiology. Gastrointestinal and liver physiology 2021 Oct 1;321(4):G436-G447
Mild hyperthermia promotes immune checkpoint blockade-based immunotherapy against metastatic pancreatic cancer using size-adjustable nanoparticles.
Yu Q, Tang X, Zhao W, Qiu Y, He J, Wan D, Li J, Wang X, He X, Liu Y, Li M, Zhang Z, He Q
Acta biomaterialia 2021 Oct 1;133:244-256
Acta biomaterialia 2021 Oct 1;133:244-256
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Elevated branched-chain α-keto acids exacerbate macrophage oxidative stress and chronic inflammatory damage in type 2 diabetes mellitus.
Liu S, Li L, Lou P, Zhao M, Wang Y, Tang M, Gong M, Liao G, Yuan Y, Li L, Zhang J, Chen Y, Cheng J, Lu Y, Liu J
Free radical biology & medicine 2021 Nov 1;175:141-154
Free radical biology & medicine 2021 Nov 1;175:141-154
The role of TLR4/MyD88/NF-κB pathway in periodontitis-induced liver inflammation of rats.
Yue Y, Liu X, Li Y, Xia B, Yu W
Oral diseases 2021 May;27(4):1012-1021
Oral diseases 2021 May;27(4):1012-1021
Melatonin alleviates LPS-induced endoplasmic reticulum stress and inflammation in spermatogonial stem cells.
Yang D, Wei Y, Lu Q, Qin D, Zhang M, Du X, Xu W, Yu X, He C, Li N, Peng S, Li G, Hua J
Journal of cellular physiology 2021 May;236(5):3536-3551
Journal of cellular physiology 2021 May;236(5):3536-3551
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Li W, Chen M, Feng X, Song M, Shao M, Yang Y, Zhang L, Liu Q, Lv L, Su X
Brain and behavior 2021 May;11(5):e02133
Brain and behavior 2021 May;11(5):e02133
Effects of carotid baroreceptor stimulation on aortic remodeling in obese rats.
Yu Q, Shu L, Wang L, Gao K, Wang J, Dai M, Cao Q, Zhang Y, Luo Q, Hu B, Dai D, Chen J, Bao M
Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 May 6;31(5):1635-1644
Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 May 6;31(5):1635-1644
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis.
Wang P, Cui Y, Ren Q, Yan B, Zhao Y, Yu P, Gao G, Shi H, Chang S, Chang YZ
Cell death & disease 2021 May 5;12(5):447
Cell death & disease 2021 May 5;12(5):447
Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma.
Yin W, Zhu H, Tan J, Xin Z, Zhou Q, Cao Y, Wu Z, Wang L, Zhao M, Jiang X, Ren C, Tang G
Cancer cell international 2021 May 25;21(1):276
Cancer cell international 2021 May 25;21(1):276
Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.
Pan H, Shi C, Yang R, Xi G, Lu C, Yang X, Chen J, Wang X, Chen L, Pan J
Journal of materials chemistry. B 2021 May 19;9(19):4039-4049
Journal of materials chemistry. B 2021 May 19;9(19):4039-4049
Alleviation of acute pancreatitis-associated lung injury by inhibiting the p38 mitogen-activated protein kinase pathway in pulmonary microvascular endothelial cells.
Zhang XX, Wang HY, Yang XF, Lin ZQ, Shi N, Chen CJ, Yao LB, Yang XM, Guo J, Xia Q, Xue P
World journal of gastroenterology 2021 May 14;27(18):2141-2159
World journal of gastroenterology 2021 May 14;27(18):2141-2159
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats.
Liu X, Man S, Luo C, Liu Y, Liu Y, Liu C, Gao W
Environmental toxicology 2021 Mar;36(3):386-395
Environmental toxicology 2021 Mar;36(3):386-395
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Zhang Y, Sun J, Dong Y, Shen X, Zhang Z
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.
Zhang GQ, Jiao Q, Shen CT, Song HJ, Zhang HZ, Qiu ZL, Luo QY
Cancer science 2021 Mar;112(3):997-1010
Cancer science 2021 Mar;112(3):997-1010
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Li H, Zhao K, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus.
Beyer DKE, Mattukat A, Freund N
International journal of bipolar disorders 2021 Mar 8;9(1):9
International journal of bipolar disorders 2021 Mar 8;9(1):9
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
Xiao Y, Cong M, Li J, He D, Wu Q, Tian P, Wang Y, Yang S, Liang C, Liang Y, Wen J, Liu Y, Luo W, Lv X, He Y, Cheng DD, Zhou T, Zhao W, Zhang P, Zhang X, Xiao Y, Qian Y, Wang H, Gao Q, Yang QC, Yang Q, Hu G
Cancer cell 2021 Mar 8;39(3):423-437.e7
Cancer cell 2021 Mar 8;39(3):423-437.e7
PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1.
Saito K, Mitsui A, Sumardika IW, Yokoyama Y, Sakaguchi M, Kondo E
International journal of oncology 2021 Jun;58(6)
International journal of oncology 2021 Jun;58(6)
Sanweidoukou decoction, a Chinese herbal formula, ameliorates β-amyloid protein-induced neuronal insult via modulating MAPK/NF-κB signaling pathways: Studies in vivo and in vitro.
An FM, Liu Z, Xuan XR, Liu QS, Wei CX
Journal of ethnopharmacology 2021 Jun 12;273:114002
Journal of ethnopharmacology 2021 Jun 12;273:114002
Visfatin regulates Pg LPS-induced proinflammatory/prodegradative effects in healthy and inflammatory periodontal cells partially via NF-κB pathway.
Yao S, Jiang C, Zhang H, Gao X, Guo Y, Cao Z
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042
Biochimica et biophysica acta. Molecular cell research 2021 Jul;1868(8):119042
Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis.
Pei L, Le Y, Chen H, Feng J, Liu Z, Zhu J, Wang C, Chen L, Dou X, Lu D
Fitoterapia 2021 Jul;152:104922
Fitoterapia 2021 Jul;152:104922
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Zhang H, Li S, Lu J, Jin J, Zhu G, Wang L, Yan Y, He L, Wang B, Wang X, Yu H
Aging 2021 Jul 8;13(13):17690-17706
Aging 2021 Jul 8;13(13):17690-17706
Intestinal Klebsiella pneumoniae infection enhances susceptibility to epileptic seizure which can be reduced by microglia activation.
Lin P, Lin A, Tao K, Yang M, Ye Q, Chen H, Chen Y, Ma Y, Lin Z, He M, Wang X, Tian X
Cell death discovery 2021 Jul 7;7(1):175
Cell death discovery 2021 Jul 7;7(1):175
Gancaonin N from Glycyrrhiza uralensis Attenuates the Inflammatory Response by Downregulating the NF-κB/MAPK Pathway on an Acute Pneumonia In Vitro Model.
Ko HM, Lee SH, Jee W, Jung JH, Kim KI, Jung HJ, Jang HJ
Pharmaceutics 2021 Jul 6;13(7)
Pharmaceutics 2021 Jul 6;13(7)
WITHDRAWN: Immunohistochemical study of inflammatory responses in septa arising from type I intestinal atresia.
Liu X, Hao P, Xie X, Li Y, Li S, Song Y, Feng C, Ye M, Wei Y, Zhao P, Li L, Jin ZW
Histology and histopathology 2021 Jul 27;:18364
Histology and histopathology 2021 Jul 27;:18364
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Tang H, Zhang P, Zeng L, Zhao Y, Xie L, Chen B
Stem cell research & therapy 2021 Jul 16;12(1):409
Stem cell research & therapy 2021 Jul 16;12(1):409
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization.
Ding J, Yang C, Cheng Y, Wang J, Zhang S, Yan S, He F, Yin T, Yang J
International immunopharmacology 2021 Jan;90:106788
International immunopharmacology 2021 Jan;90:106788
Shenyan Kangfu tablet alleviates diabetic kidney disease through attenuating inflammation and modulating the gut microbiota.
Chen Q, Ren D, Wu J, Yu H, Chen X, Wang J, Zhang Y, Liu M, Wang T
Journal of natural medicines 2021 Jan;75(1):84-98
Journal of natural medicines 2021 Jan;75(1):84-98
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Evodiamine inhibits high-fat diet-induced colitis-associated cancer in mice through regulating the gut microbiota.
Zhu LQ, Zhang L, Zhang J, Chang GL, Liu G, Yu DD, Yu XM, Zhao MS, Ye B
Journal of integrative medicine 2021 Jan;19(1):56-65
Journal of integrative medicine 2021 Jan;19(1):56-65
Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist.
Li Q, Liu W, Gao S, Mao Y, Xin Y
BMC immunology 2021 Jan 28;22(1):11
BMC immunology 2021 Jan 28;22(1):11
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Suprabasin-derived bioactive peptides identified by plasma peptidomics.
Taguchi T, Kodera Y, Oba K, Saito T, Nakagawa Y, Kawashima Y, Shichiri M
Scientific reports 2021 Jan 13;11(1):1047
Scientific reports 2021 Jan 13;11(1):1047
Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats.
Yao Y, Liu T, Yin L, Man S, Ye S, Ma L
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2138-2148
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2138-2148
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Wang C, Xu T, Lachance BB, Zhong X, Shen G, Xu T, Tang C, Jia X
Journal of neuroinflammation 2021 Feb 18;18(1):50
Journal of neuroinflammation 2021 Feb 18;18(1):50
Clinical and genomic characteristics of metabolic syndrome in colorectal cancer.
Li Y, Zhao J, Wu X, Zhang Y, Jin Y, Cai W
Aging 2021 Feb 11;13(4):5442-5460
Aging 2021 Feb 11;13(4):5442-5460
Effect of dihydromyricetin on hepatic encephalopathy associated with acute hepatic failure in mice.
Cheng L, Wang X, Ma X, Xu H, Yang Y, Zhang D
Pharmaceutical biology 2021 Dec;59(1):557-564
Pharmaceutical biology 2021 Dec;59(1):557-564
Long-term ketamine administration induces bladder damage and upregulates autophagy-associated proteins in bladder smooth muscle tissue.
Li Y, Dong Z, Wen G, Ren X, Ren W, Yan L, Wang X, Yu H, Wu X, Xia X, Lu Y, Wu X
Environmental toxicology 2021 Dec;36(12):2521-2529
Environmental toxicology 2021 Dec;36(12):2521-2529
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Gu JY, Xu YW, Feng LP, Dong J, Zhao LQ, Liu C, Wang HY, Zhang XY, Song C, Wang CH
Brain research bulletin 2021 Dec;177:252-262
Brain research bulletin 2021 Dec;177:252-262
HIF1A-AS2 induces osimertinib resistance in lung adenocarcinoma patients by regulating the miR-146b-5p/IL-6/STAT3 axis.
Si J, Ma Y, Lv C, Hong Y, Tan H, Yang Y
Molecular therapy. Nucleic acids 2021 Dec 3;26:613-624
Molecular therapy. Nucleic acids 2021 Dec 3;26:613-624
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.
Pan S, Zhang Y, Huang M, Deng Z, Zhang A, Pei L, Wang L, Zhao W, Ma L, Zhang Q, Cui D
Biomaterials 2021 Aug;275:120946
Biomaterials 2021 Aug;275:120946
METTL3/N6-methyladenosine/ miR-21-5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF-κB pathway activation.
Liu E, Lv L, Zhan Y, Ma Y, Feng J, He Y, Wen Y, Zhang Y, Pu Q, Ji F, Yang X, Wen JG
Journal of cellular and molecular medicine 2021 Aug;25(16):7660-7674
Journal of cellular and molecular medicine 2021 Aug;25(16):7660-7674
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Tian L, Wang S, Zhao L, Lu X, Zhu C, Gong H, Yang W
FEBS open bio 2021 Aug;11(8):2236-2244
FEBS open bio 2021 Aug;11(8):2236-2244
Nr2e1 deficiency aggravates insulin resistance and chronic inflammation of visceral adipose tissues in a diet-induced obese mice model.
He G, Gu J, Wang H, Cheng S, Xiong Q, Ke M, Hu Y, Feng J, Song L, Liu Z, Xu Y
Life sciences 2021 Aug 1;278:119562
Life sciences 2021 Aug 1;278:119562
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Tian S, Liao L, Zhou Q, Huang X, Zheng P, Guo Y, Deng T, Tian X
Oncology letters 2021 Apr;21(4):286
Oncology letters 2021 Apr;21(4):286
Interleukin-6 as an enhancer of anti-angiogenic therapy for ovarian clear cell carcinoma.
Seki T, Yanaihara N, Shapiro JS, Saito M, Tabata J, Yokomizo R, Noguchi D, Kuroda T, Kawabata A, Suzuki J, Takahashi K, Matsuzawa H, Miyake M, Takenaka M, Iida Y, Yanagida S, Okamoto A
Scientific reports 2021 Apr 8;11(1):7689
Scientific reports 2021 Apr 8;11(1):7689
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity.
Phasuk S, Jasmin S, Pairojana T, Chang HK, Liang KC, Liu IY
Molecular brain 2021 Apr 19;14(1):72
Molecular brain 2021 Apr 19;14(1):72
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Qi B, Yang C, Zhu Z, Chen H
Frontiers in cell and developmental biology 2020;8:574940
Frontiers in cell and developmental biology 2020;8:574940
Dietary Ziziphus jujuba Fruit Attenuates Colitis-Associated Tumorigenesis: A Pivotal Role of the NF-κB/IL-6/JAK1/STAT3 Pathway.
Periasamy S, Wu WH, Chien SP, Liu CT, Liu MY
Nutrition and cancer 2020;72(1):120-132
Nutrition and cancer 2020;72(1):120-132
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-[Formula: see text]B Signaling Pathway.
Ke SY, Liu DH, Wu L, Yu XG, Wang M, Shi GY, Wen RH, Zhou B, Hao BS, Liu Y, Zhu JM, Qian XX
The American journal of Chinese medicine 2020;48(6):1369-1383
The American journal of Chinese medicine 2020;48(6):1369-1383
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, Chi T, Zou L, Wang S, He Z
Oxidative medicine and cellular longevity 2020;2020:7950457
Oxidative medicine and cellular longevity 2020;2020:7950457
Huoxin Pill Attenuates Cardiac Inflammation by Suppression of TLR4/NF-κB in Acute Myocardial Ischemia Injury Rats.
Chu J, Zhou X, Peng M, Lu Y, Farman A, Peng L, Gao H, Li Q, Chen X, Xie L, Chen Y, Shen A, Peng J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7905902
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7905902
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model.
Yang K, Fan B, Zhao Q, Ji Y, Liu P, Gao S, Ren T, Dou Y, Pei M, Yang H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7291075
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7291075
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Almoiliqy M, Wen J, Qaed E, Sun Y, Lian M, Mousa H, Al-Azab M, Zaky MY, Chen D, Wang L, Al-Sharabi A, Liu Z, Sun P, Lin Y
Oxidative medicine and cellular longevity 2020;2020:4196548
Oxidative medicine and cellular longevity 2020;2020:4196548
The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells.
Sun H, Ding JM, Zheng HH, Lv KJ, Hu YF, Luo YH, Wu X, Pei WJ, Wang LZ, Wu MC, Zhang Y, Gao JL
Mediators of inflammation 2020;2020:3560793
Mediators of inflammation 2020;2020:3560793
ATP-Sensitive Potassium Channels Mediate the Cardioprotective Effect of Panax notoginseng Saponins against Myocardial Ischaemia-Reperfusion Injury and Inflammatory Reaction.
Ning K, Jiang L, Hu T, Wang X, Liu A, Bao Y
BioMed research international 2020;2020:3039184
BioMed research international 2020;2020:3039184
Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments.
Wang H, Ding Y, Zhang W, Wei K, Pei Y, Zou C, Zhang C, Ding J, Fang H, Tan S
Drug design, development and therapy 2020;14:921-931
Drug design, development and therapy 2020;14:921-931
Maternal 25-Hydroxyvitamin D Deficiency Promoted Metabolic Syndrome and Downregulated Nrf2/CBR1 Pathway in Offspring.
Zheng J, Liu X, Zheng B, Zheng Z, Zhang H, Zheng J, Sun C, Chen H, Yang J, Wang Z, Lin M, Chen J, Zhou Q, Zheng Z, Xu X, Ying H
Frontiers in pharmacology 2020;11:97
Frontiers in pharmacology 2020;11:97
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Zhang Q, Wang L, Jiang J, Lin S, Luo A, Zhao P, Tan W, Zhang M
Frontiers in immunology 2020;11:2040
Frontiers in immunology 2020;11:2040
A Novel Antidiabetic Monomers Combination Alleviates Insulin Resistance Through Bacteria-Cometabolism-Inflammation Responses.
Han L, Zhao LH, Zhang ML, Li HT, Gao ZZ, Zheng XJ, Wang XM, Wu HR, Zheng YJ, Jiang XT, Ding QY, Yang HY, Jia WP, Tong XL
Frontiers in microbiology 2020;11:173
Frontiers in microbiology 2020;11:173
TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation.
Wan YM, Wu HM, Li YH, Xu ZY, Yang JH, Liu C, He YF, Wang MJ, Wu XN, Zhang Y
Frontiers in pharmacology 2020;11:10
Frontiers in pharmacology 2020;11:10
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Liu C, Ding R, Huang W, Miao L, Li J, Li Y
Pharmacology 2020;105(3-4):231-242
Pharmacology 2020;105(3-4):231-242
Upregulated MELK Leads to Doxorubicin Chemoresistance and M2 Macrophage Polarization via the miR-34a/JAK2/STAT3 Pathway in Uterine Leiomyosarcoma.
Zhang Z, Sun C, Li C, Jiao X, Griffin BB, Dongol S, Wu H, Zhang C, Cao W, Dong R, Yang X, Zhang Q, Kong B
Frontiers in oncology 2020;10:453
Frontiers in oncology 2020;10:453
Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization.
Yan C, Ma Z, Ma H, Li Q, Zhai Q, Jiang T, Zhang Z, Wang Q
Molecular neurobiology 2020 Sep;57(9):3875-3890
Molecular neurobiology 2020 Sep;57(9):3875-3890
Dexmedetomidine ameliorates postoperative cognitive dysfunction by inhibiting Toll-like receptor 4 signaling in aged mice.
Zhou XY, Liu J, Xu ZP, Fu Q, Wang PQ, Wang JH, Zhang H
The Kaohsiung journal of medical sciences 2020 Sep;36(9):721-731
The Kaohsiung journal of medical sciences 2020 Sep;36(9):721-731
Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats.
Hu W, Wu X, Yu D, Zhao L, Zhu X, Li X, Huang T, Chu Z, Xu Y
Experimental neurology 2020 Sep;331:113374
Experimental neurology 2020 Sep;331:113374
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission.
Zhou LY, Yao M, Tian ZR, Liu SF, Song YJ, Ye J, Li G, Sun YL, Cui XJ, Wang YJ
Journal of neurochemistry 2020 Sep;155(2):154-176
Journal of neurochemistry 2020 Sep;155(2):154-176
Qingda granules attenuate hypertensive cardiac remodeling and inflammation in spontaneously hypertensive rats.
Wu X, Shen A, Bao L, Wu M, Lin X, Wang H, Chen Y, Cai Q, Lin S, Zhou X, Lu Y, Peng M, Chen D, Chu J, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110367
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110367
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Wang Y, Zhang L, Wu Y, Zhu R, Wang Y, Cao Y, Long W, Ji C, Wang H, You L
Stem cell research & therapy 2020 Sep 23;11(1):414
Stem cell research & therapy 2020 Sep 23;11(1):414
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Jia K, Dai Y, Liu A, Li X, Wu L, Lu L, Bao Y, Jin Q
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
Journal of cardiovascular pharmacology 2020 Oct;76(4):452-460
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Zajaczkowska R, Kwiatkowski K, Pawlik K, Piotrowska A, Rojewska E, Makuch W, Wordliczek J, Mika J
Pharmacological reports : PR 2020 Oct;72(5):1310-1322
Pharmacological reports : PR 2020 Oct;72(5):1310-1322
Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies.
Chang Z, Wang JL, Jing ZC, Ma P, Xu QB, Na JR, Tian J, Ma X, Zhou W, Zhou R
Phytotherapy research : PTR 2020 Oct;34(10):2730-2744
Phytotherapy research : PTR 2020 Oct;34(10):2730-2744
C/EBPγ is a critical negative regulator of LPS-/IgG immune complex-induced acute lung injury through the downregulation of C/EBPβ-/C/EBPδ-dependent C/EBP transcription activation.
Yan C, Zhang L, Yang L, Zhang Q, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13696-13710
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Oct;34(10):13696-13710
Impact of chitosan membrane culture on the expression of pro- and anti-inflammatory cytokines in mesenchymal stem cells.
Yi P, Xu X, Qiu B, Li H
Experimental and therapeutic medicine 2020 Oct;20(4):3695-3702
Experimental and therapeutic medicine 2020 Oct;20(4):3695-3702
Pachymic acid protects oocyte by improving the ovarian microenvironment in polycystic ovary syndrome mice†.
Fu XP, Xu L, Fu BB, Wei KN, Liu Y, Liao BQ, He SW, Wang YL, Chen MH, Lin YH, Li FP, Hong ZW, Huang XH, Xu CL, Wang HL
Biology of reproduction 2020 Oct 29;103(5):1085-1098
Biology of reproduction 2020 Oct 29;103(5):1085-1098
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, Peng Z, Xue Y, Peng H, Xuan L, Pan G
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Toxicology and applied pharmacology 2020 Oct 1;404:115169
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
Feng Z, Pang L, Chen S, Pang X, Huang Y, Qiao Q, Wang Y, Vonglorkham S, Huang Q, Lin X, Wei J
International immunopharmacology 2020 Nov;88:107003
International immunopharmacology 2020 Nov;88:107003
CP-25 improves nephropathy in collagen-induced arthritis rats by inhibiting the renal inflammatory response.
Wang C, Wei X, Wu Y, Tang H, Wang B, Wang Y, Sun W, Asenso J, Xiao F, Wei W
International immunopharmacology 2020 Nov;88:106997
International immunopharmacology 2020 Nov;88:106997
Dihydroartemisinin prevents dextran sodium sulphate-induced colitisthrough inhibition of the activation of NLRP3 inflammasome and p38 MAPK signaling.
Liang R, Chen W, Fan H, Chen X, Zhang J, Zhu JS
International immunopharmacology 2020 Nov;88:106949
International immunopharmacology 2020 Nov;88:106949
miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis.
Li J, Guo Y, Chen YY, Liu Q, Chen Y, Tan L, Zhang SH, Gao ZR, Zhou YH, Zhang GY, Feng YZ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14234-14249
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Nov;34(11):14234-14249
KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.
Yang X, Yang R, Chen M, Zhou Q, Zheng Y, Lu C, Bi J, Sun W, Huang T, Li L, Gong J, Li X, Hui Q, Wang X
BMJ open diabetes research & care 2020 May;8(1)
BMJ open diabetes research & care 2020 May;8(1)
Proinflammatory and regulatory mechanisms in allergic contact dermatitis caused by methylchloroisothiazolinone and methylisothiazolinone.
Goes HFO, Virgens AR, de Carvalho GC, Pietrobon AJ, Branco ACCC, Oliveira LMDS, Fernandes IG, Pereira NV, Sotto MN, Dos Reis VMS, Sato MN
Experimental dermatology 2020 May;29(5):490-498
Experimental dermatology 2020 May;29(5):490-498
Chitosan-calcium alginate dressing promotes wound healing: A preliminary study.
Zhao WY, Fang QQ, Wang XF, Wang XW, Zhang T, Shi BH, Zheng B, Zhang DD, Hu YY, Ma L, Tan WQ
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2020 May;28(3):326-337
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2020 May;28(3):326-337
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.
Wang N, Lu K, Qu H, Wang H, Chen Y, Shan T, Ge X, Wei Y, Zhou P, Xia J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109876
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109876
Pterostilbene Ameliorates Glycemic Control, Dyslipidemia and Liver Injury in Type 2 Diabetes Rats.
Zhang YJ, Sun HL, Wang T, Liu XX, Liu C, Shen F, Wang BY, Ding RR, Liu YM, Huang GY, Li WJ, Li X
Biomedical and environmental sciences : BES 2020 May 20;33(5):365-368
Biomedical and environmental sciences : BES 2020 May 20;33(5):365-368
Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission.
Zhou L, Yao M, Tian Z, Song Y, Sun Y, Ye J, Li G, Sng KS, Xu L, Cui X, Wang Y
Free radical biology & medicine 2020 May 20;152:697-714
Free radical biology & medicine 2020 May 20;152:697-714
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, Tan P, Xia X, Du Y, Fu W
Life sciences 2020 May 15;249:117517
Life sciences 2020 May 15;249:117517
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Zhou S, Chen S, Xie W, Guo X, Zhao J
Neuropeptides 2020 Jun;81:102006
Neuropeptides 2020 Jun;81:102006
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, Li Z, Cheng J, Guan S, Sun S, Chu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
Qiu J, Peng P, Xin M, Wen Z, Chen Z, Lin S, Kuang M, Fu Y, Fang G, Li S, Li C, Mao J, Qin L, Ding Y
Biomaterials science 2020 Jun 7;8(11):3147-3163
Biomaterials science 2020 Jun 7;8(11):3147-3163
RGS12 Is a Novel Critical NF-κB Activator in Inflammatory Arthritis.
Yuan G, Yang S, Ng A, Fu C, Oursler MJ, Xing L, Yang S
iScience 2020 Jun 26;23(6):101172
iScience 2020 Jun 26;23(6):101172
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Shen XF, Cheng Y, Dong QR, Zheng MQ
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Yadav VK, Huang YJ, George TA, Wei PL, Sumitra MR, Ho CL, Chang TH, Wu ATH, Huang HS
Cancers 2020 Jun 16;12(6)
Cancers 2020 Jun 16;12(6)
CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats.
Ho CY, Lin YT, Chen HH, Ho WY, Sun GC, Hsiao M, Lu PJ, Cheng PW, Tseng CJ
Journal of neuroinflammation 2020 Jun 12;17(1):185
Journal of neuroinflammation 2020 Jun 12;17(1):185
Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis.
Dong X, Kong F, Liu C, Dai S, Zhang Y, Xiao F, Zhang H, Wu CT, Wang H
Stem cell research & therapy 2020 Jun 10;11(1):229
Stem cell research & therapy 2020 Jun 10;11(1):229
Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved.
Chaudhari S, Yazdizadeh Shotorbani P, Tao Y, Davis ME, Mallet RT, Ma R
American journal of physiology. Renal physiology 2020 Jun 1;318(6):F1478-F1488
American journal of physiology. Renal physiology 2020 Jun 1;318(6):F1478-F1488
Chronotherapy targeting cytokine secretion attenuates collagen-induced arthritis in mice.
Yaekura A, Yoshida K, Morii K, Oketani Y, Okumura I, Kaneshiro K, Shibanuma N, Sakai Y, Hashiramoto A
International immunopharmacology 2020 Jul;84:106549
International immunopharmacology 2020 Jul;84:106549
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, Chu L
International immunopharmacology 2020 Jul;84:106548
International immunopharmacology 2020 Jul;84:106548
Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury.
Albashari A, He Y, Zhang Y, Ali J, Lin F, Zheng Z, Zhang K, Cao Y, Xu C, Luo L, Wang J, Ye Q
ACS omega 2020 Jul 7;5(26):16064-16075
ACS omega 2020 Jul 7;5(26):16064-16075
Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment.
Man S, Yao J, Lv P, Liu Y, Yang L, Ma L
Food & function 2020 Jul 22;11(7):6422-6432
Food & function 2020 Jul 22;11(7):6422-6432
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, Sun S, Chu X, Cheng J, Guan S, Li Z, Chu L
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Deng J, Xu T, Yang J, Zhang KM, Li Q, Yu XY, Li R, Fu J, Jiang Q, Ma JX, Chen YM
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
Supplementation of Inulin with Various Degree of Polymerization Ameliorates Liver Injury and Gut Microbiota Dysbiosis in High Fat-Fed Obese Mice.
Du H, Zhao A, Wang Q, Yang X, Ren D
Journal of agricultural and food chemistry 2020 Jan 22;68(3):779-787
Journal of agricultural and food chemistry 2020 Jan 22;68(3):779-787
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Liu D, Dong Z, Xiang F, Liu H, Wang Y, Wang Q, Rao J
Neurochemical research 2020 Feb;45(2):437-454
Neurochemical research 2020 Feb;45(2):437-454
Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model.
Luo Y, Pang XX, Ansari AR, Wu XT, Li HZ, Zhang ZW, Song H
Inflammation 2020 Feb;43(1):109-122
Inflammation 2020 Feb;43(1):109-122
IL (Interleukin)-6 Contributes to Deep Vein Thrombosis and Is Negatively Regulated by miR-338-5p.
Zhang Y, Zhang Z, Wei R, Miao X, Sun S, Liang G, Chu C, Zhao L, Zhu X, Guo Q, Wang B, Li X
Arteriosclerosis, thrombosis, and vascular biology 2020 Feb;40(2):323-334
Arteriosclerosis, thrombosis, and vascular biology 2020 Feb;40(2):323-334
IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes.
Rajendran S, Anquetil F, Quesada-Masachs E, Graef M, Gonzalez N, McArdle S, Chu T, Krogvold L, Dahl-Jørgensen K, von Herrath M
Clinical immunology (Orlando, Fla.) 2020 Feb;211:108320
Clinical immunology (Orlando, Fla.) 2020 Feb;211:108320
PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury.
Yang L, Sun YY, Liu YR, Yin NN, Bu FT, Yu HX, Du XS, Li J, Huang C
Toxicology letters 2020 Feb 1;319:11-21
Toxicology letters 2020 Feb 1;319:11-21
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, Yang W, Zhang R, Tang Y, Shi L, Li R, Tao K
Free radical biology & medicine 2020 Feb 1;147:23-36
Free radical biology & medicine 2020 Feb 1;147:23-36
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Polysaccharides from the Fleshy Fruits of Camellia oleifera Attenuate the Kidney Injury in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Li J, Xie F, Zhu X, Hu H, Fang X, Huang Z, Liu Z, Wu S
Journal of medicinal food 2020 Dec;23(12):1275-1286
Journal of medicinal food 2020 Dec;23(12):1275-1286
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Zhao Z, Li J, Zheng B, Liang Y, Shi J, Zhang J, Han X, Chu L, Chu X, Gao Y
Molecular medicine reports 2020 Dec;22(6):5271-5281
Molecular medicine reports 2020 Dec;22(6):5271-5281
Disruption of retinoid homeostasis induces RBP4 overproduction in diabetes: O-GlcNAcylation involved.
Shin SJ, Chen CH, Kuo WC, Chan HC, Chan HC, Lin KD, Ke LY
Metabolism: clinical and experimental 2020 Dec;113:154403
Metabolism: clinical and experimental 2020 Dec;113:154403
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Wang X, Yu H, Wang C, Liu Y, You J, Wang P, Xu G, Shen H, Yao H, Lan X, Zhao R, Wu X, Zhang G
Toxicology 2020 Dec 15;446:152625
Toxicology 2020 Dec 15;446:152625
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Liu JH, Yue T, Luo ZW, Cao J, Yan ZQ, Jin L, Wan TF, Shuai CJ, Wang ZG, Zhou Y, Xu R, Xie H
Disease models & mechanisms 2020 Dec 1;13(11)
Disease models & mechanisms 2020 Dec 1;13(11)
Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis.
Xu S, Jiang C, Liu H, Zhang H, Liao H, Wang X, Yao S, Ma L, Guo Y, Cao Z
Inflammation 2020 Aug;43(4):1488-1497
Inflammation 2020 Aug;43(4):1488-1497
TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.
Zhang C, Jia Y, Liu B, Wang G, Zhang Y
Life sciences 2020 Aug 1;254:117762
Life sciences 2020 Aug 1;254:117762
MicroRNA-34a deficiency leads to impaired wound closure by augmented inflammation in mice.
Zhao N, Wang G, Long S, Hu M, Gao J, Ran X, Wang J, Su Y, Wang T
Annals of translational medicine 2020 Apr;8(7):447
Annals of translational medicine 2020 Apr;8(7):447
COMP in the Infrapatellar Fat Pad-Results of a Prospective Histological, Immunohistological, and Biochemical Case-Control Study.
Grevenstein D, Heilig J, Dargel J, Oppermann J, Eysel P, Brochhausen C, Niehoff A
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Apr;38(4):747-758
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Apr;38(4):747-758
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, Wang Y, Yan W, Zhou Z, Yang H
Neurotoxicity research 2020 Apr;37(4):913-925
Neurotoxicity research 2020 Apr;37(4):913-925
The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation.
Zhang M, Fan H, Tan S, Tang Q, Liu X, Zuo D, Liao Y, Nan Z, Tan C
Journal of ethnopharmacology 2020 Apr 6;251:112549
Journal of ethnopharmacology 2020 Apr 6;251:112549
LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
Sun X, Thorne RF, Zhang XD, He M, Li J, Feng S, Liu X, Wu M
EMBO reports 2020 Apr 3;21(4):e48796
EMBO reports 2020 Apr 3;21(4):e48796
Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment.
Liu Y, Zhang X, Yan D, Wang Y, Wang N, Liu Y, Tan A, Chen X, Yan H
Toxicology and applied pharmacology 2020 Apr 15;393:114949
Toxicology and applied pharmacology 2020 Apr 15;393:114949
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
You S, Liu S, Dong X, Li H, Zhu Y, Hu L
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway.
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, Zhao Y, Deng W, Zhu T
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
American journal of physiology. Lung cellular and molecular physiology 2020 Apr 1;318(4):L723-L741
Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation.
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, Zhang A, Jia Z, Huang S
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F994-F1005
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Dai X, Zhang S, Cheng H, Cai D, Chen X, Huang Z
Frontiers in oncology 2019;9:1089
Frontiers in oncology 2019;9:1089
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6.
Dai X, Cheng H, Chen X, Li T, Zhang J, Jin G, Cai D, Huang Z
International journal of biological sciences 2019;15(5):1030-1041
International journal of biological sciences 2019;15(5):1030-1041
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Xu F, Hou B, Zhu X, Liu Y, Shi X, Li S, Li Z, Cai W, Zhou Y, Qiu L
Acta parasitologica 2019 Sep;64(3):520-527
Acta parasitologica 2019 Sep;64(3):520-527
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
Lu H, Cheng S, Wu C, Zheng S, Hong W, Liu L, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Zhong X, Xiao Q, Liu Z, Wang W, Lai CH, Yang W, Yue P, Ye Q, Xiao J
Molecular medicine reports 2019 Sep;20(3):2101-2110
Molecular medicine reports 2019 Sep;20(3):2101-2110
TLR4 gene in the regulation of periodontitis and its molecular mechanism.
Qi W, Yang X, Ye N, Li S, Han Q, Huang J, Wu B
Experimental and therapeutic medicine 2019 Sep;18(3):1961-1966
Experimental and therapeutic medicine 2019 Sep;18(3):1961-1966
Exploration of the mechanisms of Ge Gen Decoction against influenza A virus infection.
Geng ZK, Li YQ, Cui QH, DU RK, Tian JZ
Chinese journal of natural medicines 2019 Sep;17(9):650-662
Chinese journal of natural medicines 2019 Sep;17(9):650-662
Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.
Wang L, Qiu JG, He J, Liu WJ, Ge X, Zhou FM, Huang YX, Jiang BH, Liu LZ
Toxicology and applied pharmacology 2019 Sep 1;378:114603
Toxicology and applied pharmacology 2019 Sep 1;378:114603
Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways.
Wu Y, Lin Z, Yan Z, Wang Z, Fu X, Yu K
International immunopharmacology 2019 Oct;75:105715
International immunopharmacology 2019 Oct;75:105715
LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression.
Xue X, Luo L
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2465-2480
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2465-2480
Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis.
Chen X, Pan H, Li J, Zhang G, Cheng S, Zuo N, Zhao Q, Peng Z
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899
Journal of cellular biochemistry 2019 Oct;120(10):16888-16899
IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling.
Yu J, Ming H, Li HY, Yu B, Chu M, Zhu H, Zhu X
Toxicology and applied pharmacology 2019 Oct 15;381:114732
Toxicology and applied pharmacology 2019 Oct 15;381:114732
M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis.
Zhu LF, Li L, Wang XQ, Pan L, Mei YM, Fu YW, Xu Y
Oral diseases 2019 Nov;25(8):1972-1982
Oral diseases 2019 Nov;25(8):1972-1982
Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation.
Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin XY, Kojima S, Fujimoto J
Scientific reports 2019 Nov 26;9(1):17558
Scientific reports 2019 Nov 26;9(1):17558
Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway.
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, Fan X, Guo C, Wu J
International immunopharmacology 2019 May;70:435-445
International immunopharmacology 2019 May;70:435-445
Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis.
Zhang T, Liu L, Lai W, Zeng Y, Xu H, Lan Q, Su P, Chu Z
Oncology reports 2019 May;41(5):2790-2802
Oncology reports 2019 May;41(5):2790-2802
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, Zhang H, Bo T, Zhou X, Yu Y, Zhang H, Zhao M, Wang L, Yu C, Gao L, Jiang W, Zhang Q, Zhao J
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Wang R, Dong Z, Lan X, Liao Z, Chen M
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways.
Meng G, Zhou X, Wang M, Zhou L, Wang Z, Wang M, Deng J, Wang Y, Zhou Z, Zhang Y, Lai Y, Zhang Q, Yang X, Yu L, Jiang H
EBioMedicine 2019 Jun;44:656-664
EBioMedicine 2019 Jun;44:656-664
Three kinds of corneal host cells contribute differently to corneal neovascularization.
Yu H, Sun L, Cui J, Li Y, Yan Y, Wei X, Wang C, Song F, Jiang W, Liu Y, Ge H, Qian H, Li X, Tang X, Liu P
EBioMedicine 2019 Jun;44:542-553
EBioMedicine 2019 Jun;44:542-553
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, Lu C, Qian R
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate.
He M, Huang XF, Gao G, Zhou T, Li W, Hu J, Chen J, Li J, Sun T
Psychoneuroendocrinology 2019 Jun;104:286-299
Psychoneuroendocrinology 2019 Jun;104:286-299
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Upregulation of IL-6 in CUL4B-deficient myeloid-derived suppressive cells increases the aggressiveness of cancer cells.
Xu Z, Li L, Qian Y, Song Y, Qin L, Duan Y, Wang M, Li P, Jiang B, Ma C, Shao C, Gong Y
Oncogene 2019 Jul;38(30):5860-5872
Oncogene 2019 Jul;38(30):5860-5872
Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway.
Fan H, Yu X, Zou Z, Zheng W, Deng X, Guo L, Jiang W, Zhan Q, Lu SH
Carcinogenesis 2019 Jul 4;40(5):669-679
Carcinogenesis 2019 Jul 4;40(5):669-679
Toxicological exploration of peptide-based cationic liposomes in siRNA delivery.
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, Shi L, Du L, Liu G, Zhang C, Xu X, Kang X, Zhen Y, Zhang S
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Colloids and surfaces. B, Biointerfaces 2019 Jul 1;179:66-76
Macrophage polarization in human gingival tissue in response to periodontal disease.
Zhou LN, Bi CS, Gao LN, An Y, Chen F, Chen FM
Oral diseases 2019 Jan;25(1):265-273
Oral diseases 2019 Jan;25(1):265-273
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, Liu P, Chi T, Ji X, Gao J, Chen C, Lang H, Xu J, Liu D, Yang Y, Qiu S, Tang X, Chen G, Zou L
Biochimica et biophysica acta. Molecular basis of disease 2019 Jan;1865(1):161-180
Biochimica et biophysica acta. Molecular basis of disease 2019 Jan;1865(1):161-180
Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.
Zhang X, Yin Y, Yue L, Gong L
Investigative ophthalmology & visual science 2019 Jan 2;60(1):407-419
Investigative ophthalmology & visual science 2019 Jan 2;60(1):407-419
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Anti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy.
Huang X, Wu B, Li J, Shang Y, Chen W, Nie X, Gui R
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):968-979
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):968-979
Inhibition of Fibroblast Growth Factor Receptor by AZD4547 Protects Against Inflammation in Septic Mice.
Huang Y, Wang F, Li H, Xu S, Xu W, Pan X, Hu Y, Mao L, Qian S, Pan J
Inflammation 2019 Dec;42(6):1957-1967
Inflammation 2019 Dec;42(6):1957-1967
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitis by regulating fatty acid degradation and microbial dysbiosis.
Chen W, Fan H, Liang R, Zhang R, Zhang J, Zhu J
Journal of cellular and molecular medicine 2019 Dec;23(12):8161-8172
Journal of cellular and molecular medicine 2019 Dec;23(12):8161-8172
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Rao S, Li Q, Wu H, Zhao M, Wang A, Zhang G, Li J, Lu L, Shi W, Lu Q
Expert review of clinical immunology 2019 Dec;15(12):1341-1350
Expert review of clinical immunology 2019 Dec;15(12):1341-1350
Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage.
Xiong Q, Wu Y, Yang M, Wu G, Wang Y, Wang H, Feng J, Song L, Tong B, He G, Xu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109503
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109503
Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression.
Narimiya T, Kanzaki H, Yamaguchi Y, Wada S, Katsumata Y, Tanaka K, Tomonari H
Bone reports 2019 Dec;11:100228
Bone reports 2019 Dec;11:100228
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, Guo Y, Han H
Virulence 2019 Dec;10(1):248-259
Virulence 2019 Dec;10(1):248-259
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
Curcumin inhibits cigarette smoke-induced inflammation via modulating the PPARγ-NF-κB signaling pathway.
Li Q, Sun J, Mohammadtursun N, Wu J, Dong J, Li L
Food & function 2019 Dec 11;10(12):7983-7994
Food & function 2019 Dec 11;10(12):7983-7994
Pigment epithelium-derived factor inhibits adipogenesis in 3T3-L1 adipocytes and protects against high-fat diet-induced obesity and metabolic disorders in mice.
Chen CC, Lee TY, Leu YL, Wang SH
Translational research : the journal of laboratory and clinical medicine 2019 Aug;210:26-42
Translational research : the journal of laboratory and clinical medicine 2019 Aug;210:26-42
Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response.
Luo W, Shen Z, Deng M, Li X, Tan B, Xiao M, Wu S, Yang Z, Zhu C, Tian L, Wu X, Meng X, Quan Y, Wang X
Molecular medicine reports 2019 Aug;20(2):1007-1016
Molecular medicine reports 2019 Aug;20(2):1007-1016
MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma.
Yokomizo R, Yanaihara N, Yamaguchi N, Saito M, Kawabata A, Takahashi K, Takenaka M, Yamada K, Shapiro JS, Okamoto A
Oncotarget 2019 Aug 6;10(47):4880-4893
Oncotarget 2019 Aug 6;10(47):4880-4893
Bioactive Constituents from the Roots of Eurycoma longifolia.
Ruan J, Li Z, Zhang Y, Chen Y, Liu M, Han L, Zhang Y, Wang T
Molecules (Basel, Switzerland) 2019 Aug 30;24(17)
Molecules (Basel, Switzerland) 2019 Aug 30;24(17)
Survival-time dependent increase in neuronal IL-6 and astroglial GFAP expression in fatally injured human brain tissue.
Trautz F, Franke H, Bohnert S, Hammer N, Müller W, Stassart R, Tse R, Zwirner J, Dreßler J, Ondruschka B
Scientific reports 2019 Aug 15;9(1):11771
Scientific reports 2019 Aug 15;9(1):11771
Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals.
Li D, Cai Z, Wu J, Zhang Y
Neurological research 2019 Apr;41(4):369-377
Neurological research 2019 Apr;41(4):369-377
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, Deng J, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.
Guo HH, Feng CL, Zhang WX, Luo ZG, Zhang HJ, Zhang TT, Ma C, Zhan Y, Li R, Wu S, Abliz Z, Li C, Li XL, Ma XL, Wang LL, Zheng WS, Han YX, Jiang JD
Nature communications 2019 Apr 30;10(1):1981
Nature communications 2019 Apr 30;10(1):1981
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Mao J, Yi M, Wang R, Huang Y, Chen M
Frontiers in pharmacology 2018;9:1469
Frontiers in pharmacology 2018;9:1469
The development of salt-sensitive hypertension regulated by PSGL-1 gene in mice.
Yang Y, Liu X, Liu Y, Fu H, Gao Y, Liu X, Jiang X
Cell & bioscience 2018;8:20
Cell & bioscience 2018;8:20
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Rao SS, Hu Y, Xie PL, Cao J, Wang ZX, Liu JH, Yin H, Huang J, Tan YJ, Luo J, Luo MJ, Tang SY, Chen TH, Yuan LQ, Liao EY, Xu R, Liu ZZ, Chen CY, Xie H
Bone research 2018;6:9
Bone research 2018;6:9
Lipocalin 2 Suppresses Ocular Inflammation by Inhibiting the Activation of NF-κβ Pathway in Endotoxin-Induced Uveitis.
Tang W, Ma J, Gu R, Ding X, Lei B, Wang X, Zhuang H, Xu G
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(1):375-388
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(1):375-388
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, Chen K, Xia Y, Niu P, Xu L, Wang F, Dai W, Zhou Y, Guo C
Mediators of inflammation 2018;2018:4032484
Mediators of inflammation 2018;2018:4032484
Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy.
Sun RZ, Fan Y, Liang X, Gong TT, Wang Q, Liu H, Shan ZY, Lei L
BioMed research international 2018;2018:1010248
BioMed research international 2018;2018:1010248
TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.
Wang FJ, Wang P, Chen LY, Geng YW, Chen H, Meng ZQ, Liu LM, Chen Z
Integrative cancer therapies 2018 Sep;17(3):707-716
Integrative cancer therapies 2018 Sep;17(3):707-716
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
Guo K, Ma J, Liang W
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Total glucosides of paeony improves the immunomodulatory capacity of MSCs partially via the miR-124/STAT3 pathway in oral lichen planus.
Zhao Z, Han Y, Zhang Z, Li W, Ji X, Liu X, Jin J, Xu S, Cui H, Cheng Z, Wang Q, Wang X, Guo X, Wang Y, Liu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:151-158
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:151-158
Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis.
Ishikawa Y, Iwata S, Hanami K, Nawata A, Zhang M, Yamagata K, Hirata S, Sakata K, Todoroki Y, Nakano K, Nakayamada S, Satoh M, Tanaka Y
Arthritis research & therapy 2018 Oct 26;20(1):240
Arthritis research & therapy 2018 Oct 26;20(1):240
Skeletal muscle secretion of IL-6 is muscle type specific: Ex vivo evidence.
Liang AP, Drazick AT, Gao H, Li Y
Biochemical and biophysical research communications 2018 Oct 20;505(1):146-150
Biochemical and biophysical research communications 2018 Oct 20;505(1):146-150
Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer.
Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Takabe K, Wakai T
The Journal of surgical research 2018 Nov;231:323-330
The Journal of surgical research 2018 Nov;231:323-330
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Journal of cellular physiology 2018 Jun;233(6):5002-5013
miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
Daguia Zambe JC, Zhai Y, Zhou Z, Du X, Wei Y, Ma F, Hua J
Journal of cellular physiology 2018 Jun;233(6):4652-4665
Journal of cellular physiology 2018 Jun;233(6):4652-4665
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis.
Zhang X, Guo J, Wang H, Zhang C, Shi N, Cai W, Jin T, Lin Z, Ma Y, Yang X, Xia Q, Xue P
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
The Tohoku journal of experimental medicine 2018 Jul;245(3):205-215
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Yan X, Lei F, Hu Y, Nie L, Jia Q, Zhou H, Zhao F, Zheng Y
Environmental toxicology and pharmacology 2018 Jan;57:151-158
Environmental toxicology and pharmacology 2018 Jan;57:151-158
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Cai W, Zhang Z, Huang Y, Sun H, Qiu L
Experimental and therapeutic medicine 2018 Jan;15(1):924-932
Experimental and therapeutic medicine 2018 Jan;15(1):924-932
Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala.
Liu Z, Liu F, Liu X, Ma C, Zhao J
Molecular pain 2018 Jan-Dec;14:1744806918805902
Molecular pain 2018 Jan-Dec;14:1744806918805902
Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury.
Fan Y, Luo Q, Wei J, Lin R, Lin L, Li Y, Chen Z, Lin W, Chen Q
Brain research 2018 Jan 15;1679:125-133
Brain research 2018 Jan 15;1679:125-133
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro.
Zhang S, Li P, Yuan Z, Tan J
Stem cell research & therapy 2018 Feb 26;9(1):48
Stem cell research & therapy 2018 Feb 26;9(1):48
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Zhou SH, Wang X, Fan MY, Li HL, Bian F, Huang T, Fang HY
Experimental and therapeutic medicine 2018 Aug;16(2):718-722
Experimental and therapeutic medicine 2018 Aug;16(2):718-722
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization.
Lu H, Wu L, Liu L, Ruan Q, Zhang X, Hong W, Wu S, Jin G, Bai Y
Biochemical pharmacology 2018 Aug;154:203-212
Biochemical pharmacology 2018 Aug;154:203-212
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity.
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y, Xu W, Zeng H
Redox biology 2018 Apr;14:237-249
Redox biology 2018 Apr;14:237-249
Ultraviolet B Inhibits IL-17A/TNF-α-Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts.
Yin L, Hu Y, Xu J, Guo J, Tu J, Yin Z
Frontiers in immunology 2017;8:91
Frontiers in immunology 2017;8:91
Effects of Ketamine on Levels of Inflammatory Cytokines IL-6, IL-1β, and TNF-α in the Hippocampus of Mice Following Acute or Chronic Administration.
Li Y, Shen R, Wen G, Ding R, Du A, Zhou J, Dong Z, Ren X, Yao H, Zhao R, Zhang G, Lu Y, Wu X
Frontiers in pharmacology 2017;8:139
Frontiers in pharmacology 2017;8:139
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465
Cell and tissue research 2017 Sep;369(3):455-465
Prognostic impact of interleukin-6 expression in stage I ovarian clear cell carcinoma.
Kawabata A, Yanaihara N, Nagata C, Saito M, Noguchi D, Takenaka M, Iida Y, Takano H, Yamada K, Iwamoto M, Kiyokawa T, Okamoto A
Gynecologic oncology 2017 Sep;146(3):609-614
Gynecologic oncology 2017 Sep;146(3):609-614
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
Zhao P, Zhou R, Zhu XY, Liu G, Zhao YP, Ma PS, Wu W, Niu Y, Sun T, Li YX, Yu JQ, Qian ZM
Neurochemical research 2017 Oct;42(10):2798-2813
Neurochemical research 2017 Oct;42(10):2798-2813
The novel preventive effect of Daikenchuto (TJ-100), a Japanese herbal drug, against neonatal necrotizing enterocolitis in rats.
Shinyama S, Kaji T, Mukai M, Nakame K, Matsufuji H, Takamatsu H, Ieiri S
Pediatric surgery international 2017 Oct;33(10):1109-1114
Pediatric surgery international 2017 Oct;33(10):1109-1114
BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.
Zhao R, Liu Y, Wang H, Yang J, Niu W, Fan S, Xiong W, Ma J, Li X, Phillips JB, Tan M, Qiu Y, Li G, Zhou M
Cellular & molecular immunology 2017 Oct;14(10):830-841
Cellular & molecular immunology 2017 Oct;14(10):830-841
Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Zhang MT, Wang B, Jia YN, Liu N, Ma PS, Gong SS, Niu Y, Sun T, Li YX, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:186-198
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:186-198
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.
Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D
Nature communications 2017 May 26;8:15584
Nature communications 2017 May 26;8:15584
hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway.
Tang X, Guo D, Lin C, Shi Z, Qian R, Fu W, Liu J, Li X, Fan L
Molecular medicine reports 2017 Mar;15(3):1401-1406
Molecular medicine reports 2017 Mar;15(3):1401-1406
Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer's disease.
Xia Z, Peng W, Cheng S, Zhong B, Sheng C, Zhang C, Gong W, Cheng S, Li J, Wang Z
Oncotarget 2017 Jun 27;8(26):42648-42663
Oncotarget 2017 Jun 27;8(26):42648-42663
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Huang YJ, Yang CK, Wei PL, Huynh TT, Whang-Peng J, Meng TC, Hsiao M, Tzeng YM, Wu AT, Yen Y
Journal of hematology & oncology 2017 Feb 28;10(1):60
Journal of hematology & oncology 2017 Feb 28;10(1):60
Diffuse large B cell lymphoma associated with chronic inflammation arising within atrial myxoma: aggressive histological features but indolent clinical behaviour.
Yan J, Luo D, Zhang F, He J, Yao S, Luo X, Xu F, Chen Y, Fu L, Xu J, Liu Y
Histopathology 2017 Dec;71(6):951-959
Histopathology 2017 Dec;71(6):951-959
Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes.
Ren H, Hu K
Molecular medicine reports 2017 Dec;16(6):8092-8102
Molecular medicine reports 2017 Dec;16(6):8092-8102
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, Song X, Song E, Song Y
Toxicology 2017 Apr 15;381:39-50
Toxicology 2017 Apr 15;381:39-50
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression.
Wang CQ, Sun HT, Gao XM, Ren N, Sheng YY, Wang Z, Zheng Y, Wei JW, Zhang KL, Yu XX, Zhu Y, Luo Q, Yang LY, Dong QZ, Qin LX
American journal of cancer research 2016;6(9):1873-1889
American journal of cancer research 2016;6(9):1873-1889
Non-toxic retention of nanoceria in murine eyes.
Cai X, Seal S, McGinnis JF
Molecular vision 2016;22:1176-1187
Molecular vision 2016;22:1176-1187
Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide.
Li L, Bian T, Lyu J, Cui D, Lei L, Yan F
International immunopharmacology 2016 Sep;38:204-13
International immunopharmacology 2016 Sep;38:204-13
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy.
Xu Y, Zhang Q, Luo D, Wang J, Duan D
International journal of biological macromolecules 2016 Oct;91:233-40
International journal of biological macromolecules 2016 Oct;91:233-40
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation.
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, Zeng Y
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
The international journal of biochemistry & cell biology 2016 Oct;79:181-193
From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft.
Fu J, Shi Q, Song X, Liu Z, Wang Y, Wang Y, Song E, Song Y
Toxicological sciences : an official journal of the Society of Toxicology 2016 Oct;153(2):303-15
Toxicological sciences : an official journal of the Society of Toxicology 2016 Oct;153(2):303-15
Elevated Level of Circulating Platelet-derived Microparticles in Oral Cancer.
Ren JG, Man QW, Zhang W, Li C, Xiong XP, Zhu JY, Wang WM, Sun ZJ, Jia J, Zhang WF, Zhao YF, Chen G, Liu B
Journal of dental research 2016 Jan;95(1):87-93
Journal of dental research 2016 Jan;95(1):87-93
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, Song E, Song Y
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MicroRNA-499 Rs3746444 polymorphism and biliary atresia.
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A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
Wang LL, Zhao R, Liu CS, Liu M, Li SS, Li JY, Jiang SK, Zhang M, Tian ZL, Wang M, Zhang MZ, Guan DW
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Journal of forensic and legal medicine 2016 Apr;39:138-46
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
Owusu L, Wang B, Du Y, Li W, Xin Y
Journal of Cancer 2015;6(2):128-38
Journal of Cancer 2015;6(2):128-38
hCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κB-Mediated Inflammatory Responses.
Tang X, Guo D, Lin C, Shi Z, Qian R, Fu W, Liu J, Li X, Fan L
Oxidative medicine and cellular longevity 2015;2015:671839
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MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NF-κB Signaling Pathway Following Negative Regulation.
Zhong J, Shi QQ, Zhu MM, Shen J, Wang HH, Ma D, Miao CH
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PloS one 2015;10(11):e0143662
Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α-Dependent Senescence-Associated Secretory Phenotype.
Gardner SE, Humphry M, Bennett MR, Clarke MC
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Arteriosclerosis, thrombosis, and vascular biology 2015 Sep;35(9):1963-74
The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure.
Wang C, Li H, Luo C, Li Y, Zhang Y, Yun D, Mu D, Zhou K, Hua Y
Placenta 2015 Oct;36(10):1138-47
Placenta 2015 Oct;36(10):1138-47
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells.
Hao S, Ji J, Zhao H, Shang L, Wu J, Li H, Qiao T, Li K
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Molecules (Basel, Switzerland) 2015 Dec 1;20(12):21287-97
N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway.
Wang C, Chen K, Xia Y, Dai W, Wang F, Shen M, Cheng P, Wang J, Lu J, Zhang Y, Yang J, Zhu R, Zhang H, Li J, Zheng Y, Zhou Y, Guo C
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PloS one 2014;9(9):e108855
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Ye Q, Zheng Y, Fan S, Qin Z, Li N, Tang A, Ai F, Zhang X, Bian Y, Dang W, Huang J, Zhou M, Zhou Y, Xiong W, Yan Q, Ma J, Li G
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PloS one 2014;9(7):e103298
Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Shen M, Lu J, Cheng P, Lin C, Dai W, Wang F, Wang C, Zhang Y, Chen K, Xu L, Zhou Y, Guo C
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PloS one 2014;9(2):e87977
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.
Wu X, He L, Chen F, He X, Cai Y, Zhang G, Yi Q, He M, Luo J
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PloS one 2014;9(11):e112891
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
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Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Hu L, Li L, Xu D, Xia X, Pi R, Xu D, Wang W, Du H, Song E, Song Y
Chemico-biological interactions 2014 Apr 25;213:51-9
Chemico-biological interactions 2014 Apr 25;213:51-9
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
Shen M, Lu J, Dai W, Wang F, Xu L, Chen K, He L, Cheng P, Zhang Y, Wang C, Wu D, Yang J, Zhu R, Zhang H, Zhou Y, Guo C
Mediators of inflammation 2013;2013:461536
Mediators of inflammation 2013;2013:461536
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 21865-1-AP( IL6 Antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Recombinant protein were subjected to SDS PAGE followed by western blot with 21865-1-AP( IL6 Antibody) at dilution of 1:3000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IL-6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IL-6. This antibody recognizes human, mouse antigen. The IL-6 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
